Actions of Albuked 25 in details
Albuked 25 is responsible for 75-80% of the colloid osmotic pressure of normal plasma. Albuked 25 stabilizes circulating blood volume and is a carrier of hormones, enzymes, medicinal products and toxins. [ ]
Albuked 25 is a protein with a total extravascular mass of approximately 160 g and an intravascular mass of about 120 g. [ ]
How should I take Albuked 25?
Albuked 25 is injected into a vein through an IV. A healthcare provider will give you this injection.
Your breathing, pulse, blood pressure, electrolyte levels, kidney function, and other vital signs will be watched closely while you are receiving Albuked 25. Your blood will also need to be tested regularly during treatment.
Drink plenty of liquids while you are being treated with Albuked 25.
Albuked 25 administration
For IV administration only. Infusion rate depends on indication and clinical situation. In emergencies, may administer as rapidly as necessary to improve clinical condition. After initial volume replacement:
5%: Do not exceed 2 to 4 mL/minute in patients with normal plasma volume; 5 to 10 mL/minute in patients with hypoproteinemia
25%: Do not exceed 1 mL/minute in patients with normal plasma volume; 2 to 3 mL/minute in patients with hypoproteinemia
Rapid infusion may cause vascular overload. Albuked 25 25% may be given undiluted or diluted in normal saline. May give in combination or through the same administration set as saline or carbohydrates. Warm to room temperature before use if large volumes are administered. Use within 4 hours after entering package; discard unused portion. Some products may require a filter; refer to product labeling. Do not use with ethanol or protein hydrolysates (precipitation may form).
Albuked 25 pharmacology
No pharmacokinetic or pharmacodynamic studies with Albuked 25 (Human) 20% have been conducted.
Mechanism of Action
Albuked 25 is responsible for 75-80% of the colloid osmotic pressure of normal plasma. Albuked 25 stabilizes circulating blood volume and is a carrier of hormones, enzymes, medicinal products and toxins. [ ]
Albuked 25 is a protein with a total extravascular mass of approximately 160 g and an intravascular mass of about 120 g. [ ]
Pharmacodynamics
The colloid osmotic effect of Albuked 25 (Human) 20% and 25% is approximately 5 times the volume administered. When injected intravenously, it will increase circulating plasma volume by approximately 3.5 times the volume infused within 15 minutes if the patient is adequately hydrated. This extra fluid reduces hemoconcentration and blood viscosity. The degree and duration of volume expansion depends upon the initial blood volume. When treating patients with diminished blood volume, the effect of infused Albuked 25 may persist for many hours. The hemodilution lasts for a shorter time when Albuked 25 is administered to individuals with normal blood volume. [ ]
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Information checked by Dr. Sachin Kumar, MD Pharmacology
