Amarin Actions

• Actions of Amarin in details
• Amarin administration
• Amarin pharmacology
• Amarin reviews

Actions of Amarin in details

Description: Amarin is an alkylamine derivative with histamine H₁-receptor antagonist effects. It also has anticholinergic and moderate sedative effects.

Onset: 15-20 min (oral).

Pharmacokinetics:

Absorption: Readily absorbed from the GI tract. Peak plasma concentrations in 1-2.5 hr.

Metabolism: Metabolised to N-desmethylpheniramine and N-didesmethylpheniramine.

Excretion: Via urine (as unchanged drug and metabolites). Terminal half-life: 8-17 hr (IV Amarin maleate); 16-19 hr (oral).

Amarin administration

Should be taken with food. Take after meals.

Amarin pharmacology

Amarin is an antihistamine used to treat allergic conditions such as hay fever or urticaria. It is generally sold in combination with other medications, rather than as a stand-alone drug. Allergies are caused by an excessive type 1 hypersensitivity response of the body to allergens, mediated by inappropriate histamine signalling. By inhibiting the binding of histamine, antihistamines decrease the normal histamine response from cells, consequently decreasing allergic symptoms.

References

1. DailyMed. "LANSOPRAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. EPA DSStox. "Lansoprazole: DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". https://comptox.epa.gov/dashboard/ds... (accessed September 17, 2018).
3. EPA DSStox. "Pheniramine: DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". https://comptox.epa.gov/dashboard/ds... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Amarin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Amarin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reviews

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Information checked by Dr. Sachin Kumar, MD Pharmacology