Boots Paracetamol Extra indications
Management of duodenal ulcer; treatment of gastroesophageal reflux disease (GERD), including erosive esophagitis; therapy for benign gastric ulcer; treatment of pathologic hypersecretory conditions; prevention of upper GI bleeding.
Unlabeled Uses
Prevention of aspiration pneumonia and stress ulcers; herpes virus infection; chronic idiopathic urticaria; anaphylaxis (relieves dermatologic symptoms only); dyspepsia; used before anesthesia to prevent aspiration pneumonitis; treatment of hyperparathyroidism and control of secondary hyperparathyroidism in chronic hemodialysis patient; treatment of chronic viral warts in children.
Boots Paracetamol Extra description
Each caplet contains acetaminophen 500 mg and Caffeine (Boots Paracetamol (Boots Paracetamol Extra) Extra) 65 mg.
Boots Paracetamol Extra dosage
Adults and Children ≥12 years: Take 1-2 caplets, every 4-6 hours as required. Do not take more frequently than every 4 hrs. Do not take more than 8 caplets in 24 hours. It can be taken on an empty stomach.
Panadol Extra Advance should not be used with other acetaminophen-containing products. Do not exceed the stated dose.
Boots Paracetamol Extra interactions
The speed of absorption of Paracetamol (Boots Paracetamol Extra) may be increased by metoclopramide or domperidone and absorption reduced by colestyramine.
The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular use of Paracetamol (Boots Paracetamol Extra) with increased risk of bleeding. Occasional doses have no significant effect.
The use of drugs which induce hepatic microsomal enzymes, such as anticonvulsants and oral contraceptive steroids, may increase the extent of metabolism of Paracetamol (Boots Paracetamol Extra), resulting in reduced plasma concentrations of the drug and a faster elimination rate.
Drugs which induce hepatic microsomal enzymes, such as alcohol and barbiturates, may increase the hepatotoxicity of Paracetamol (Boots Paracetamol Extra), particularly after overdose.
CNS depression or excitation may occur if codeine is given to patients receiving monoamine oxidase inhibitors, or within two weeks of stopping treatment with them. The effects of CNS depressants (including alcohol) may be potentiated by codeine.
Concurrent use of codeine with antidiarrhoeal and antiperistaltic agents may increase the risk of severe constipation. Concomitant use of antimuscarinics or medications with antimuscarinic action may result in an increased risk of severe constipation, which may lead to paralytic ileus and/or urinary retention.
Quinidine can inhibit the analgesic effect of codeine.
Codeine may delay the absorption of mexiletine and thus reduce the antiarrhythmic effect of the latter. Codeine may antagonise the gastrointestinal effects of metoclopramide and domperidone. Cimetidine inhibits the metabolism of opioid analgesics resulting in increased plasma concentrations.
Naltrexone blocks the therapeutic effect of opioids.
Boots Paracetamol Extra side effects
Adverse effects of Paracetamol (Boots Paracetamol Extra) are rare, but hypersensitivity including skin rash may occur. There have been a few reports of blood dyscrasias including thrombocytopenia and agranulocytosis, but these were not necessarily causally related to Paracetamol (Boots Paracetamol Extra).
Codeine can produce constipation and drowsiness. Occasional effects are nausea, vomiting, sweating, facial flushing, dry mouth, blurred or double vision, dizziness, postural hypotension, headache, vertigo, palpitations, allergic reactions (itch, skin rash, facial oedema), and difficulties in micturition (dysuria, increased frequency, decrease in amount). Side-effects which occur rarely include hallucinations, nightmares, restlessness and stomach cramps. The frequency and severity are determined by dosage, duration of treatment and individual sensitivity and are unlikely at this dosage. Tolerance and dependency can occur, especially with prolonged high doses of codeine.
High doses of Caffeine (Boots Paracetamol (Boots Paracetamol Extra) Extra) may produce headache, tremor, nervousness and irritability.
Boots Paracetamol Extra contraindications
Do not use with an MAOI or within 14 days of discontinuing an MAOI
due to risk of drug interaction. At least 5 weeks should be allowed after
stopping FLUOXETINE before treatment with an MAOI
• Do not use with pimozide due to risk of drug interaction or QTc
prolongation
• Do not use with thioridazine due to QTc interval prolongation or
potential for elevated thioridazine plasma levels. Do not use thioridazine
within 5 weeks of discontinuing FLUOXETINE
Active ingredient matches for Boots Paracetamol Extra:
Caffeine/Paracetamol in United Kingdom.
List of Boots Paracetamol Extra substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Boots Pharmaceuticals Paracetamol/Coffeïne (Netherlands) | |
Bufferin Plus (China) | |
C1000 Paracetamol/coffeine (Netherlands) | |
Caf-N (Bangladesh) | |
Cafceta (Bangladesh) | |
Cafedon (Bangladesh) | |
Cafenol (Bangladesh, Tunisia, Venezuela) | |
Cafepar (India) | |
10's (Cipla Limited) | $ 0.11 |
Cafepar 500+25 Tablet (Cipla Limited) | $ 0.01 |
Cafepar Paracetamol 500mg, Caffeine25mg TAB / 10 (Cipla Limited) | $ 0.11 |
CAFEPAR tab 10's (Cipla Limited) | $ 0.11 |
Caffeine/Paracetamol (Bangladesh, Bulgaria, Croatia (Hrvatska), Estonia, Greece, Hong Kong, Ireland, Latvia, Lithuania, Malta, New Zealand, Oman, Peru, Poland, Romania, Russian Federation, Serbia, Singapore, Slovakia, Slovenia, Switzerland, Taiwan, Tunisia, Turkey, United Kingdom, Vietnam) | |
Caffo (Bangladesh) | |
CAFIGESIC TABLET | |
CAFIGESIC TABLET 1 strip / 10 tablets each (Theo Pharma Pvt Ltd) | $ 0.17 |
Cafipar (Pakistan) | |
Cafipar 30mg/500mg Tablet (Unison Pharmaceuticals Pvt Ltd) | $ 0.01 |
CAFIPAR 500MG/25MG TABLET | |
CAFIPAR 500MG/25MG TABLET 1 strip / 10 tablets each (Unison Pharmaceuticals Pvt Ltd) | $ 0.13 |
Carmeiton (Taiwan) | |
Carmeiton | |
Cc Don Extra (Pakistan) | |
Céfaline Hauth (France) | |
Cetadol Plus (Bangladesh) | |
Cetam Plus (Bangladesh) | |
Choligrip Effect (Poland) | |
Cinepar Extra (Georgia) | |
Claradol Caféine (France) | |
Tablet, Effervescent; Oral; Acetaminophen 500 mg; Caffeine 50 mg | |
Tablet; Oral; Acetaminophen 500 mg; Caffeine 50 mg | |
Tablet, Effervescent; Oral; Acetaminophen 500 mg; Caffeine 50 mg | |
Tablet; Oral; Acetaminophen 500 mg; Caffeine 50 mg | |
Clofamol (Bangladesh) | |
Codipar Plus (Poland) | |
Tablet, Film-Coated; Oral; Acetaminophen 500 mg; Caffeine 65 mg (Gsk) | |
Colocol Extra (Vietnam) | |
Colocol Extra 6 Blister x 10 Tablet | |
Colocol Extra 10 Blister x 10 Tablet | |
COMBIFLAM PLUS | |
COMBIFLAM PLUS TABLET 1 strip / 8 tablets each (Sanofi India Ltd) | $ 0.26 |
Copyrkal (Germany) | |
Tablet; Oral; Acetaminophen; Caffeine (Berlin-chemie) | |
Cotibin Plus (Chile) | |
Cpmol Plus (Bangladesh) | |
CROCIN PAIN RELIEF (India) | |
CROCIN PAIN RELIEF Capsule/ Tablet / 50mg - 650mg / 10 units (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 0.15 |
10's (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 0.20 |
Crocin Pain Relief 650+50 Tablet (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 0.02 |
Crocin Pain Relief Paracetamol 650mg, Caffeine50mg TAB / 10 (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 0.20 |
CROCIN PAIN RELIEF TABLET 1 strip / 15 tablets each (Glaxo Smithkline Pharmaceuticals Ltd.) | $ 0.54 |
See 437 substitutes for Boots Paracetamol Extra |
References
- DailyMed. "CAFFEINE; ERGOTAMINE TARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "caffeine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "caffeine". http://www.drugbank.ca/drugs/DB00201 (accessed September 17, 2018).
Reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology