Bromifar Side effects

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Side effects of Bromifar in details

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Bromifar’s pharmacological action may lead to gastric irritation. A transient rise in serum aminotransferase values have been reported due to Bromifar.

Orciprenaline sulphate, as a sympathomimetic agent, may precipitate a wide range of adverse effects. Side-effects include fear; anxiety, restlessness, tremor, insomnia, confusion, irritability, weakness and psychotic states. Appetite may be reduced and nausea and vomiting may occur. A rise in blood pressure which may produce cerebral haemorrhage and pulmonary oedema, tachycardia and cardiac arrhythmias, anginal pain, palpitations, and cardiac arrest. Hypotension with dizziness and fainting and flushing may occur. Other effects that may occur include difficulty in micturition and urinary retention; dyspnoea; weakness; headache; disturbances of glucose metabolism; sweating and hypersalivation. Muscle cramps or twitching or unpleasant taste may occur.

Bromifar contraindications

Bromifar hydrochloride SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.

Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Bromifar hydrochloride SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.

Safety in pregnancy and lactation has not been established.


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References

  1. European Chemicals Agency - ECHA. "Bromhexine: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
  2. NIST. "Benzenemethanamine, 2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-". http://www.nist.gov/srd/nist1a.cfm (accessed September 17, 2018).
  3. KEGG. "Risk category of Japanese OTC drugs". http://www.genome.jp/kegg-bin/get_ht... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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