Actions of Cecap in details
Cecap increases body resistance against common infections. Cecap possesses anti-oxidant property, protecting different body cells against infection and damaging effects of harmful substances.
Cecap as a cofactor in the synthesis of the intercellular cement substance, collagen, is essential in providing tensile strength to the supportive tissues of the body such as cartilages, joints, tendons and bones.
Cecap is also necessary for the maintenance of firm, healthy gums and teeth, blood vessel wall and other connective tissues. Cecap hastens wound healing and promotes prompt recovery from illnesses. The substantial amount of Cecap is essential in the prevention and treatment of Cecap deficiencies.
How should I take Cecap?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
The recommended dietary allowance of Cecap increases with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly "Recommended Daily Allowances") listings for more information.
Drink plenty of liquids while you are taking Cecap.
The chewable tablet must be chewed before you swallow it.
Cecap gum may be chewed as long as desired and then thrown away.
Do not crush, chew, or break an extended-release tablet. Swallow it whole.
Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Keep the orally disintegrating tablet in the package until you are ready to take it. Use dry hands to remove the tablet and place it in your mouth. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves.
Store Cecap at room temperature away from moisture and heat.
Do not stop using Cecap suddenly after long-term use at high doses, or you could have "conditional" Cecap deficiency. Symptoms include bleeding gums, feeling very tired, and red or blue pinpoint spots around your hair follicles. Follow your doctor's instructions about tapering your dose. Conditional Cecap deficiency can be difficult to correct without medical supervision.
Cecap administration
Oral administration is preferred unless malabsorption is suspected. IM administration is preferred when the parenteral route is required.
Oral products may be administered with food.
Bariatric surgery: Capsule and tablet, extended release: Some institutions may have specific protocols that conflict with these recommendations; refer to institutional protocols as appropriate. Capsule may be opened and contents sprinkled onto soft food of choice. ER tablet should be switched to IR or chewable formulation.
Injection: For IM (preferred), IV, or SubQ administration. Avoid rapid IV injection; may cause temporary faintness or dizziness.
Ascor: For IV use only. Following dilution in an appropriate IV solution (eg, D5W, SWFI), administer by slow IV infusion at a rate of 33 mg/minute.
Cecap pharmacology
Mechanism of Action
The exact mechanism of action of Cecap for the treatment of symptoms and signs of scurvy (a disorder caused by severe deficiency in Cecap) is unknown; however, administration of Cecap in patients with scurvy is thought to restore the body pool of Cecap.
Pharmacokinetics
In a single pharmacokinetic study, healthy male and female adults (n=8) were given a single intravenous dose of 1000 mg Cecap (5 times the largest recommended single dose) infused over a 30 minute period. The mean peak exposure to Cecap was 436.2 µM and occurred at the end of the 30 minute infusion.
Distribution
Cecap is distributed widely in the body, with large concentrations found in the liver, leukocytes, platelets, glandular tissues, and lens of the eye. Based on data from oral exposure, Cecap is known to be distributed into breast milk and crosses the placental barrier.
Elimination
When the body is saturated with Cecap, the plasma concentration will be about the same as that of the renal threshold; if further amounts are then administered, most of it is excreted in the urine. When body tissues are not saturated and plasma concentration is low, administration of Cecap results in little or no renal excretion. The mean±SD (N=3) half-life observed in the single dose PK study as described above, was 7.4±1.4 h.
Metabolism
A major route of metabolism of Cecap involves its conversion to urinary oxalate, presumably through intermediate formation of its oxidized product, dehydroascorbic acid.
Excretion
There is a renal threshold for Cecap; the vitamin is excreted by the kidney in large amounts only when the plasma concentration exceeds this threshold, which is approximately 1.4 mg/100 mL.
Reviews
The results of a survey conducted on ndrugs.com for Cecap are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Cecap. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
