Dosage of Cecon 500 in details
Important Preparation and Administration Instructions
- Cecon 500 vials contain 25, 000 mg of Cecon 500 and the largest recommended single dose is 200 mg. Do not give the entire contents of the vial to a single patient.
- Do not administer Cecon 500 as an undiluted intravenous sensitive.
- Minimize exposure to light because Cecon 500 is light sensitive.
- Cecon 500 is supplied as a Pharmacy Bulk Package (PBP) which is intended for dispensing of single doses to multiple patients in a pharmacy admixture program and is restricted to the preparation of admixtures for infusion:
a. Use only in a suitable ISO Class 5 work area such as a laminar flow hood (or an equivalent clean air compounding area)
b. Penetrate each PBP vial closure only one time with a suitable sterile transfer device or dispensing set that allows measured dispensing of the contents. Given that pressure may develop within the vial during storage, excercise caution when withdrawing contents from the vial.
c. Once the closure system has been penetrated, complete all dispensing from the PBP vial within 4 hours. Each dose must be used immediately. Discard unused portion.
d. Prior to administration, Cecon 500 must be diluted in a suitable infusion solution and the final solution for infusion must be isotonic (undiluted the osmolarity of Cecon 500 is approximately 5,900 mOsmol/L). Prior to preparing the admixture for infusion, calculate the osmolarity of the intended admixture for infusion. Add one daily dose of Cecon 500 directly to an appropriate volume of a suitable infusion solution (e.g., 5% Dextrose Injection, Sterile Water for Injection) and add appropriate solutes, as necessary, to make final solution isotonic. Sterile Water for Injection is highly hypotonic; adjust solute content, as necessary, to make thet final infusion solution isotonic prior to injection. Do not mix Cecon 500 with solutions containing elemental compounds that can be reduced (e.g., copper). The concentration of Cecon 500 in the final, admixture solution for infusion is to be the range of 1 to 25 mg of Cecon 500 per mL. For example, for the largest recommended dose:
Add 200 mg of Cecon 500 (equivalent to 0.4 mL of Cecon 500) to 7.5 mL of Sterile Water for Injection to produce an infusion solution having an approximate osmolarity of 290 mOsmol/L. In this specific example, addition of solute is NOT necessary because the solution is isotonic.
e. Prepare the recommended dose based on the patient population [ see Dosage and Administration (2.2), (2.3)].
f. Visually inspect for particulate matter and discoloration prior to administration (the diluted Cecon 500 solution should appear colorless to pale yellow).
g. Immediately administer the admixture for infusion as a slow intravenous infusion [ see Recommended Dosage, (2.2)]
Recommended Dosage
Table 1 provides recommended doses of Cecon 500 based on patient population and infusion rates of diluted Cecon 500 solution.
| Patient Population | Cecon 500 Once Daily Dose (mg) | Infusion Rate of Diluted Cecon 500 Solution (mg/minute) |
| Pediatric Patients age 5 months to less than 12 months | 50 | 1.3 |
| Pediatric Patients age 1 year to less than 11 years | 100 | 3.3 |
| Adults and Pediatric Patients 11 years and older | 200 | 33 |
The recommended maximum duration of daily treatment with Cecon 500 is seven days. If no improvement in scorbutic symptoms is observed after one week of treatment, retreat until resolution of scorbutic symptoms is observed.
Repeat dosing is not recommended in pediatric patients less than 11 years of age.
Dosage Reductions in Specific Populations
Women who are pregnant or lactating and patients with glucose-6-dehydrogenase deficiency should not exceed the U.S. Recommended Dietary Allowance (RDA) or daily Adequate Intake (AI) level for Cecon 500 for their age group and condition [ see Warnings and Precautions (5.2) and Use in Specific Populations (8.1, 8.2)].
What other drugs will affect Cecon 500?
Other drugs may interact with Cecon 500, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Cecon 500 interactions
In an application with barbiturates, primidone increases the excretion of Cecon 500 in the urine.
With the simultaneous use of oral contraceptives reduces the concentration of Cecon 500 in blood plasma.
In an application of Rhea Cecon 500 with iron preparations Cecon 500, due to its regenerative properties, transforms ferric iron in the bivalent, which improves its absorption.
Cecon 500 in high doses can decrease urine pH that while the application reduces the tubular reabsorption of amphetamine and tricyclic antidepressants.
With the simultaneous use of aspirin reduces the absorption of Cecon 500 by about a third.
Rhea Cecon 500 in an application with warfarin may decrease effects of warfarin.
With the simultaneous application of Cecon 500 increases the excretion of iron in patients receiving deferoxamine. In the application of Cecon 500 at a dose of 500 mg / day possibly left ventricular dysfunction.
In an application with tetracycline is increased excretion of Cecon 500 in the urine.
There is a described case of reducing the concentration of fluphenazine in plasma in patients treated with Cecon 500 500 mg 2 times / day.
May increase the concentration of ethinyl estradiol in the blood plasma in its simultaneous application in the oral contraceptives.
Reviews
The results of a survey conducted on ndrugs.com for Cecon 500 are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Cecon 500. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported frequency of use
How frequently do I need to take Cecon 500?It was reported by ndrugs.com website users that Cecon 500 should ideally be taken Once in a day as the most common frequency of the Cecon 500. You should you adhere strictly to the instructions and guidelines provided by your doctor on how frequently this Cecon 500 should be taken. Get another patient's view on how frequent the capsule should be used by clicking here.
| Users | % | ||
|---|---|---|---|
| Once in a day | 1 | 100.0% | |
2 consumers reported doses
What doses of Cecon 500 drug you have used?The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Cecon 500 drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
| Users | % | ||
|---|---|---|---|
| 501mg-1g | 1 | 50.0% | |
| 201-500mg | 1 | 50.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
