Cecrisina Actions

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Actions of Cecrisina in details

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Cecrisina increases body resistance against common infections. Cecrisina possesses anti-oxidant property, protecting different body cells against infection and damaging effects of harmful substances.

Cecrisina as a cofactor in the synthesis of the intercellular cement substance, collagen, is essential in providing tensile strength to the supportive tissues of the body such as cartilages, joints, tendons and bones.

Cecrisina is also necessary for the maintenance of firm, healthy gums and teeth, blood vessel wall and other connective tissues. Cecrisina hastens wound healing and promotes prompt recovery from illnesses. The substantial amount of Cecrisina is essential in the prevention and treatment of Cecrisina deficiencies.

How should I take Cecrisina?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

The recommended dietary allowance of Cecrisina (Cecrisina) increases with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly "Recommended Daily Allowances") listings for more information.

Drink plenty of liquids while you are taking Cecrisina.

The chewable tablet must be chewed before you swallow it.

Cecrisina gum may be chewed as long as desired and then thrown away.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Keep the orally disintegrating tablet in the package until you are ready to take it. Use dry hands to remove the tablet and place it in your mouth. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Swallow several times as the tablet dissolves.

Store Cecrisina at room temperature away from moisture and heat.

Do not stop using Cecrisina suddenly after long-term use at high doses, or you could have "conditional" Cecrisina deficiency. Symptoms include bleeding gums, feeling very tired, and red or blue pinpoint spots around your hair follicles. Follow your doctor's instructions about tapering your dose. Conditional Cecrisina deficiency can be difficult to correct without medical supervision.

Cecrisina administration

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Oral administration is preferred unless malabsorption is suspected. IM administration is preferred when the parenteral route is required.

Oral products may be administered with food.

Bariatric surgery: Capsule and tablet, extended release: Some institutions may have specific protocols that conflict with these recommendations; refer to institutional protocols as appropriate. Capsule may be opened and contents sprinkled onto soft food of choice. ER tablet should be switched to IR or chewable formulation.

Injection: For IM (preferred), IV, or SubQ administration. Avoid rapid IV injection; may cause temporary faintness or dizziness.

Ascor: For IV use only. Following dilution in an appropriate IV solution (eg, D5W, SWFI), administer by slow IV infusion at a rate of 33 mg/minute.

Cecrisina pharmacology

Mechanism of Action

The exact mechanism of action of Cecrisina for the treatment of symptoms and signs of scurvy (a disorder caused by severe deficiency in Cecrisina) is unknown; however, administration of Cecrisina in patients with scurvy is thought to restore the body pool of Cecrisina.

Pharmacokinetics

In a single pharmacokinetic study, healthy male and female adults (n=8) were given a single intravenous dose of 1000 mg Cecrisina (5 times the largest recommended single dose) infused over a 30 minute period. The mean peak exposure to Cecrisina was 436.2 µM and occurred at the end of the 30 minute infusion.

Distribution

Cecrisina is distributed widely in the body, with large concentrations found in the liver, leukocytes, platelets, glandular tissues, and lens of the eye. Based on data from oral exposure, Cecrisina is known to be distributed into breast milk and crosses the placental barrier.

Elimination

When the body is saturated with Cecrisina, the plasma concentration will be about the same as that of the renal threshold; if further amounts are then administered, most of it is excreted in the urine. When body tissues are not saturated and plasma concentration is low, administration of Cecrisina results in little or no renal excretion. The mean±SD (N=3) half-life observed in the single dose PK study as described above, was 7.4±1.4 h.

Metabolism

A major route of metabolism of Cecrisina involves its conversion to urinary oxalate, presumably through intermediate formation of its oxidized product, dehydroascorbic acid.

Excretion

There is a renal threshold for Cecrisina; the vitamin is excreted by the kidney in large amounts only when the plasma concentration exceeds this threshold, which is approximately 1.4 mg/100 mL.


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Reviews

The results of a survey conducted on ndrugs.com for Cecrisina are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Cecrisina. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported administration

When best can I take Cecrisina, on an empty stomach, before or after food?
ndrugs.com website users have also released a report stating that Cecrisina should be taken Before food. In any case, this may not be the right description on how you ought to take this Cecrisina. Kindly visit your doctor for more medical advice in this regard. Click here to see other users view on when best the Cecrisina can be taken.
Users%
Before food1
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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