Pregnancy of Ceftrum in details
One uncontrolled study of pregnant women between 19 and 21 weeks gestation has suggested that Ceftrum serum concentrations are approximately 50% those expected in nonpregnant women.
Ceftrum has been assigned to pregnancy category B by the FDA. Animal studies have failed to reveal any evidence of teratogenicity. There are no controlled data in human pregnancy. Ceftrum should only be given during pregnancy when need has been clearly established.
See references
Ceftrum breastfeeding
Ceftrum is excreted into human milk in small amounts. Ceftrum is considered compatible with breast-feeding by the American Academy of Pediatrics. The manufacturer recommends that caution be used when administering Ceftrum to nursing women.
See references
References for pregnancy information
- Giamarellou H, Gazis J, Petrikkos G, et al "A study of cefoxitin, moxalactam, and Ceftrum kinetics in pregnancy." Am J Obstet Gynecol 147 (1983): 914-9
- Heikkila A, Erkkola R "Review of beta-lactam antibiotics in pregnancy - the need for adjustment of dosage schedules." Clin Pharmacokinet 27 (1994): 49-62
- "Product Information. Fortaz (Ceftrum)." Glaxo Wellcome, Research Triangle Park, NC.
- Nathorstboos J, Philipson A, Hedman A, Arvisson A "Renal elimination of Ceftrum during pregnancy." Am J Obstet Gynecol 172 (1995): 163-6
References for breastfeeding information
- Blanco JD, Jorgensen JH, Castaneda YS, Crawford SA "Ceftrum levels in human breast milk." Antimicrob Agents Chemother 23 (1983): 479-80
- Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
- "Product Information. Fortaz (Ceftrum)." Glaxo Wellcome, Research Triangle Park, NC.
References
- DailyMed. "CEFTAZIDIME: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubMed Health. "Tazicef: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
- Human Metabolome Database (HMDB). "Ceftazidime: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology