What is Cetoconazol Neo Quimica?
Cetoconazol Neo Quimica is used to treat infections caused by a fungus or yeast. It works by killing the fungus or yeast or preventing its growth.
Cetoconazol Neo Quimica cream is used to treat:
- Athlete's foot (tinea pedis; ringworm of the foot);
- Ringworm of the body (tinea corporis);
- Ringworm of the groin (tinea cruris; jock itch);
- Seborrheic dermatitis;
- "Sun fungus" (tinea versicolor; pityriasis versicolor); and
- Yeast infection of the skin (cutaneous candidiasis).
Cetoconazol Neo Quimica foam or gel is used to treat seborrheic dermatitis (scaly areas on your skin or scalp).
Cetoconazol Neo Quimica 1% shampoo is used to treat dandruff.
Cetoconazol Neo Quimica 2% shampoo is used to treat "sun fungus" (tinea versicolor; pityriasis versicolor).
Cetoconazol Neo Quimica may also be used for other fungus infections of the skin as determined by your doctor.
Most forms of Cetoconazol Neo Quimica are available only with your doctor's prescription. Some forms are available without a prescription. However, your doctor may have special instructions on the proper use for your medical condition.
Cetoconazol Neo Quimica indications
Cetoconazol Neo Quimica is an imidazole antifungal administered topically or by mouth. It is given by mouth in chronic mucocutaneous or vaginal candidiasis, in fungal infections of the gastrointestinal tract, in dermatophyte infections of the skin and fingernails not responding to topical treatment, and in systemic infections including blastomycosis, candidiasis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis.
It has been given for the prophylaxis of fungal infections in immunocompromised patients, although fluconazole or itraconazole are usually preferred. It has been recommended that, because of its erratic absorption and slow therapeutic response, Cetoconazol Neo Quimica should not be used for the treatment of life-threatening fungal infections, including fungal meningitis, or for severe infections in immunocompromised patients. Also, because of the risk of hepatotoxicity the use of Cetoconazol Neo Quimica in nonsystemic fungal infections tends to be restricted to serious infections resistant to other treatment.
How should I use Cetoconazol Neo Quimica?
Use Cetoconazol Neo Quimica gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Cetoconazol Neo Quimica gel. Talk to your pharmacist if you have questions about this information.
- Wash your hands before and immediately after using Cetoconazol Neo Quimica gel.
- Spread a thin layer of Cetoconazol Neo Quimica gel onto the affected area with the tips of your fingers. Gently rub it in. Be sure to cover the entire affected area and the healthy skin around it.
- Do not touch your eyes or nose while you are applying Cetoconazol Neo Quimica gel.
- Wait for at least 20 minutes after you apply Cetoconazol Neo Quimica gel before you apply makeup or sunscreen.
- Do not wash the area where you applied Cetoconazol Neo Quimica gel for at least 3 hours after you apply it.
- If you miss a dose of Cetoconazol Neo Quimica gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Cetoconazol Neo Quimica gel.
Uses of Cetoconazol Neo Quimica in details
Use: Labeled Indications
Fungal infections (systemic):
US labeling: Treatment of susceptible systemic fungal infections, including blastomycosis, histoplasmosis, paracoccidioidomycosis, coccidioidomycosis, and chromomycosis in patients who have failed or who are intolerant to other antifungal therapies
Limitations of use: Cetoconazol Neo Quimica should only be used when other effective antifungal therapy is not available or tolerated and the potential benefits outweigh the potential risks. Cetoconazol Neo Quimica tablets are not indicated for the treatment of onychomycosis, cutaneous dermatophyte infections, or Candida infections.
Canadian labeling: Treatment of serious or life-threatening systemic fungal infections (eg, systemic candidiasis, chronic mucocutaneous candidiasis, coccidioidomycosis, paracoccidioidomycosis, histoplasmosis, and chromomycosis) where alternate therapy is inappropriate or ineffective; may be considered for severe dermatophytoses unresponsive to other therapy
Off Label Uses
Cushing syndrome
Data from a retrospective multicenter study support the use of Cetoconazol Neo Quimica in the management of patients with Cushing disease. The study authors found the side effects of Cetoconazol Neo Quimica to be acceptable; however, close monitoring of liver enzymes is advised. Additional trials may be necessary to further define the role of Cetoconazol Neo Quimica in this condition.
Based on the Endocrine Society
Cetoconazol Neo Quimica description
Cetoconazol Neo Quimica contains the following ingredients: D-Water, maltodextrin (corn), partially hydrolyzed sodium caseinate, lactalbumin hydrolysate, canola oil, medium-chain triglycerides (fractionated coconut oil), L-arginine, corn oil, magnesium chloride, potassium citrate, tribasic calcium phosphate, citric acid, soy lecithin, ascorbic acid, dibasic potassium phosphate, choline chloride, carrageenan, potassium chloride, taurine, L-carnitine, zinc sulfate, ferrous sulfate, α-tocopheryl acetate, niacinamide, calcium pantothenate, manganese sulfate, β-carotene, cupric sulfate, thiamine chloride HCl, pyridoxine HCl, riboflavin, vitamin A palmitate, folic acid, biotin, chromium chloride, sodium molybdate, potassium iodide, sodium selenate, phylloquinone, cyanocobalamin and vitamin D3.
Cetoconazol Neo Quimica is a ready-to-feed enteral product as a supplemental or sole-source nutrition complete and balanced nutrition for tube feeding. It is calorie dense at 1.3 cal/mL and contains a protein system of partially hydrolyzed proteins, including peptides and amino acids, to utilize the dual absorption system of the gut. Cetoconazol Neo Quimica is lactose- and gluten-free.
Caloric Distribution: See Table 1.
Analysis: See Table 2.
Cetoconazol Neo Quimica dosage
Cetoconazol Neo Quimica Dosage
Generic name: Cetoconazol Neo Quimica 200mg
Dosage form: tablet
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
There should be laboratory as well as clinical documentation of infection prior to starting Cetoconazol Neo Quimica therapy. The usual duration of therapy for systemic infection is 6 months. Treatment should be continued until active fungal infection has subsided.
Adults
The recommended starting dose of Cetoconazol Neo Quimica® (Cetoconazol Neo Quimica) Tablets is a single daily administration of 200 mg (one tablet). If clinical responsiveness is insufficient within the expected time, the dose of Cetoconazol Neo Quimica® Tablets may be increased to 400 mg (two tablets) once daily.
Children
In small numbers of children over 2 years of age, a single daily dose of 3.3 to 6.6 mg/kg has been used. Cetoconazol Neo Quimica® Tablets have not been studied in children under 2 years of age.
More about Cetoconazol Neo Quimica (Cetoconazol Neo Quimica)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- En Espanol
- 4 Reviews - Add your own review/rating
Consumer resources
- Cetoconazol Neo Quimica
- Cetoconazol Neo Quimica (Advanced Reading)
Professional resources
- Cetoconazol Neo Quimica (AHFS Monograph)
- Cetoconazol Neo Quimica (FDA)
Other formulations
- Cetoconazol Neo Quimica
Topical
- Cetoconazol Neo Quimica A-D
Related treatment guides
- Blastomycosis
- Chromomycosis
- Coccidioidomycosis
- Histoplasmosis
- Paracoccidioidomycosis
Cetoconazol Neo Quimica interactions
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What other drugs will affect Cetoconazol Neo Quimica?
Cetoconazol Neo Quimica is a potent inhibitor of the cytochrome P450 3A4 enzyme system. Coadministration of Cetoconazol Neo Quimica Tablets and drugs primarily metabolized by the cytochrome P450 3A4 enzyme system may result in increased plasma concentrations of the drugs that could increase or prolong both therapeutic and adverse effects.
Cetoconazol Neo Quimica Tablets inhibit the metabolism of terfenadine, resulting in an increased plasma concentration of terfenadine.
Cetoconazol Neo Quimica inhibits the metabolism of astemizole. Cetoconazol Neo Quimica potently inhibits the metabolism of cisapride resulting in a mean eight-fold increase in AUC of cisapride.
Cetoconazol Neo Quimica Tablets may alter the metabolism of cyclosporine, tacrolimus, and methylprednisolone, resulting in elevated plasma concentrations of the latter drugs.
Coadministration of Cetoconazol Neo Quimica Tablets with midazolam or triazolam has resulted in elevated plasma concentrations of the latter two drugs.
It is, therefore, advisable to monitor digoxin concentrations in patients receiving Cetoconazol Neo Quimica.
When taken orally, imidazole compounds like Cetoconazol Neo Quimica may enhance the anticoagulant effect of coumarin-like drugs.
a potential interaction involving the latter agents when used concomitantly with Cetoconazol Neo Quimica Tablets (an imidazole) can not be ruled out.
Concomitant administration of Cetoconazol Neo Quimica Tablets with phenytoin may alter the metabolism of one or both of the drugs.
Concomitant administration of rifampin with Cetoconazol Neo Quimica Tablets reduces the blood levels of the latter. INH (isoniazid) is also reported to affect Cetoconazol Neo Quimica concentrations adversely.
Cetoconazol Neo Quimica side effects
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What are the possible side effects of Cetoconazol Neo Quimica?
Topically applied Cetoconazol Neo Quimica appears to have a low order of toxicity and is generally well tolerated. Adverse effects have been reported in up to 5% of patients receiving Cetoconazol Neo Quimica 2% cream and have consisted principally of local reactions such as severe irritation, pruritus, and stinging. A painful allergic reaction, consisting of localized swelling and inflammation, occurred in at least one patient receiving Cetoconazol Neo Quimica 2% cream and contact dermatitis occurred in another.
In several studies evaluating the potential of topical Cetoconazol Neo Quimica for causing dermal irritation, contact sensitization, or phototoxic or photoallergenic reactions in healthy adults, topical application of Cetoconazol Neo Quimica 2% cream caused mild transient erythema in some individuals, but did not cause contact sensitization of the delayed hypersensitivity type, irritation, phototoxicity, or photocontact sensitization.
Contact dermatitis has been reported following topical application of imidazole-derivative azole antifungals (e.g., clotrimazole, econazole, miconazole, oxiconazole, sulconazole, tioconazole). Cross-sensitization appears to occur among the imidazole derivatives; however, cross-sensitivity appears to be unpredictable. The fact that patients with contact sensitivity to one imidazole-derivative azole antifungal may be sensitive to other similar drugs should be considered.
Although hepatotoxicity has occurred during treatment with oral Cetoconazol Neo Quimica, it is unlikely that this adverse effect would occur with Cetoconazol Neo Quimica 2% cream since the drug does not appear to be appreciably absorbed following topical application to skin.
Adverse effects reported in patients receiving topical Cetoconazol Neo Quimica 2% as a shampoo applied to the skin include pruritus, application site reaction, and dry skin. Adverse effects reported in patients receiving Cetoconazol Neo Quimica shampoo to the scalp include increased hair loss, irritation, abnormal hair texture, scalp pustules, dry skin, pruritus, and oiliness or dryness of the hair and scalp. In some patients with permanently waved (“permed”) hair, use of Cetoconazol Neo Quimica 2% shampoo resulted in loss of the curl.
Cetoconazol Neo Quimica contraindications
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What is the most important information I should know about Cetoconazol Neo Quimica?
Drug Interactions
Coadministration of a number of CYP3A4 substrates such as dofetilide, quinidine cisapride and pimozide is contraindicated with Cetoconazol Neo Quimica® Tablets. Coadministration with Cetoconazol Neo Quimica can cause elevated plasma concentrations of these drugs and may increase or prolong both therapeutic and adverse effects to such an extent that a potentially serious adverse reaction may occur. For example, increased plasma concentrations of some of these drugs can lead to QT prolongation and sometimes resulting in life-threatening ventricular tachyarrhythmias including occurrences of torsades de pointes, a potentially fatal arrhythmia.
Additionally, the following other drugs are contraindicated with Cetoconazol Neo Quimica® Tablets: methadone, disopyramide, dronedarone, ergot alkaloids such as dihydroergotamine, ergometrine, ergotamine, methylergometrine, irinotecan, lurasidone, oral midazolam, alprazolam, triazolam, felodipine, nisoldipine, ranolazine, tolvaptan, eplerenone, lovastatin, simvastatin and colchicine.
Enhanced Sedation
Coadministration of Cetoconazol Neo Quimica® Tablets with oral midazolam, oral triazolam or alprazolam has resulted in elevated plasma concentrations of these drugs. This may potentiate and prolong hypnotic and sedative effects, especially with repeated dosing or chronic administration of these agents. Concomitant administration of Cetoconazol Neo Quimica® Tablets with oral triazolam, oral midazolam or alprazolam is contraindicated.
Myopathy
Coadministration of CYP3A4 metabolized HMG-CoA reductase inhibitors such as simvastatin, and lovastatin is contraindicated with Cetoconazol Neo Quimica® Tablets.
Ergotism
Concomitant administration of ergot alkaloids such as dihydroergotamine and ergotamine with Cetoconazol Neo Quimica® Tablets is contraindicated.
Liver Disease
The use of Cetoconazol Neo Quimica® Tablets is contraindicated in patients with acute or chronic liver disease.
Hypersensitivity
Cetoconazol Neo Quimica® is contraindicated in patients who have shown hypersensitivity to the drug.
Active ingredient matches for Cetoconazol Neo Quimica:
Ketoconazole in Brazil.
List of Cetoconazol Neo Quimica substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Cetoconazol Teuto (Brazil) | |
| Cetoderm (Brazil) | |
| Cetohexal (Brazil) | |
| Cetomed (Brazil) | |
| Cetomicoss (Brazil) | |
| Cetomicóss (Brazil) | |
| Cetomizol (Brazil) | |
| Cetonax (Brazil) | |
| Cetoneo (Brazil) | |
| Cetoneo Xampu (Brazil) | |
| Cetonin (Brazil) | |
| Cetoprox (Brazil) | |
| Cetozan (Brazil) | |
| Cetozaz (Brazil) | |
| Cetozol (Brazil) | |
| Chemicon (Ecuador) | |
| Chenfu (Taiwan) | |
| Chenfu 20 mg/1 g x 1 g | |
| Chenfu 20 mg/1 g x 5 g | |
| Chenfu 20 mg/1 g x 10 g | |
| Chenfu 20 mg/1 g x 15 g | |
| Chenfu 20 mg/1 g x 20 g | |
| Chintaral (Thailand) | |
| Chintaral 2 % x 100 mL (Chinta) | |
| Chintaral shampoo 2 % 100 mL x 1's (Chinta) | |
| Chintoral (Thailand) | |
| Chintoral 200 mg x 25 x 10's | |
| Chintoral 2 % x 5 g x 12's | |
| Ciclofung (Colombia) | |
| Clarazole (Bahrain, Oman) | |
| Clear Shampoo (Taiwan) | |
| Clear Shampoo 2 % x 10 mL | |
| Clear Shampoo 2 % x 100 mL | |
| Clear Shampoo 2 % x 200 mL | |
| Clear Shampoo 2 % x 1 L | |
| Clear Shampoo 2 % x 2000 mL | |
| Clear Shampoo 2 % x 3785 mL | |
| Cleartop (Brazil) | |
| Clopeta-C (India) | |
| Clopeta-C Ketoconazole 2 % w/v, Cetrimide 0.5 % w/w. SOAP / 50g (Auriga) | $ 0.78 |
| 50g (Auriga) | $ 0.78 |
| CLOPETA-C soap 50g (Auriga) | $ 0.78 |
| Clopeta-Z (India) | |
| Clopeta-Z Ketoconazole 2 % w/v, Zincpyrithione 1 % w/v. SHAMPOO / 60ml (Auriga) | |
| 60ml (Auriga) | |
| CLOPETA-Z shampoo 60ml (Auriga) | |
| Comozel (Vietnam) | |
| Comozel 1 tube x 10 g | |
| Comozel 1 tube 10 g | |
See 2050 substitutes for Cetoconazol Neo Quimica | |
References
- DailyMed. "KETOCONAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "ketoconazole". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "ketoconazole". http://www.drugbank.ca/drugs/DB01026 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Cetoconazol Neo Quimica are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Cetoconazol Neo Quimica. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
