Dosage of Char-Flo with Sorbitol in details
Char-Flo with Sorbitol Dosage
Applies to the following strength(s): 25 g; 50 g; 15 g; 260 mg; 250 mg; 200 mg; 30 g
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Gastrointestinal Decontamination
- Flatulence
Usual Pediatric Dose for:
- Gastrointestinal Decontamination
- Flatulence
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Precautions
- Dialysis
- Other Comments
Usual Adult Dose for Gastrointestinal Decontamination
Activated Char-Flo with Sorbitol:
Single-dose: 25 to 100 g orally or by nasogastric tube once, as a slurry in water. The routine use of single-dose activated Char-Flo with Sorbitol is not recommended.
Multiple-dose:
Initial dose: 50 to 100 g orally or by nasogastric tube, as a slurry in water
Maintenance dose: 12.5 g every hour, 25 g every 2 hours, or 50 g every 4 hours until symptoms resolve.
Usual Adult Dose for Flatulence
Capsules and tablets: 500 to 1040 mg up to 4 times daily as needed. Not effective in the treatment of poisoning.
Usual Pediatric Dose for Gastrointestinal Decontamination
Activated Char-Flo with Sorbitol:
Administer aqueous suspension or as a slurry in water.
Single dose:
<1 year: 0.5 to 1 g/kg or 10 to 25 g orally or by nasogastric tube once
1-12 years: 0.5 to 1 g/kg or 25 to 50 g orally or by nasogastric tube once
13-18 years: Single-dose: 25 to 100 g orally or by nasogastric tube once
The routine use of single-dose activated Char-Flo with Sorbitol is not recommended.
Multiple-dose:
<13 years: Initial dose: 10 to 25 g orally or by nasogastric tube, as a slurry in water
Maintenance dose: 1 to 2 g/kg every 2 to 4 hours
13-18 years: Initial dose: 50 to 100 g orally or by nasogastric tube, as a slurry in water
Maintenance dose: 12.5 g every hour, 25 g every 2 hours, or 50 g every 4 hours until toxic symptoms resolve.
Usual Pediatric Dose for Flatulence
3 to 18 years:
Capsules and tablets: 500 to 1040 mg up to 4 times daily as needed. Not effective in the treatment of poisoning.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
No adjustment recommended
Precautions
The routine use of single-dose activated Char-Flo with Sorbitol for the management of poisoning is not recommended.
Administration is contraindicated in the presence of an unprotected airway, in patients with or at risk of gastrointestinal hemorrhage, perforation, or obstruction, or if administration would increase the risk of aspiration (i.e., hydrocarbon ingestion).
Caution is recommended in patients with poor gastrointestinal motility.
Should not be used in the management of acute corrosive or petroleum distillate ingestion since vomiting can occur following Char-Flo with Sorbitol administration. Char-Flo with Sorbitol may also obscure the endoscopic evaluation of gastroesophageal lesions.
May be administered in an attempt to adsorb any ingested toxic agent (where physical or other contraindications are not present), but it is known to be much less effective in the adsorption of boric acid, cadmium, cyanide, DDT, ethanol, ethylene glycol, iron, lead, lithium, mercury, methanol, potassium chloride, selenium, strong acid or alkali (may obscure lesion on endoscopy), and organic solvents.
Minimum dilution: 240 mL water per 20 to 30 g Char-Flo with Sorbitol.
Milk, chocolate syrup, ice cream, and sherbet should not be mixed with Char-Flo with Sorbitol because they may reduce its efficacy.
Activated Char-Flo with Sorbitol may adsorb therapeutic agents while it remains in the GI tract. Dosages or route of administration of therapeutic drugs may need to be altered.
Char-Flo with Sorbitol tablets and capsules are ineffective for the treatment of poisoning due to inferior adsorptive capacity.
Dialysis
No adjustment recommended
Other Comments
For gastrointestinal decontamination, time since ingestion is a critical criterion in the decision to use Char-Flo with Sorbitol for decontamination purposes. Typically, the recommended cutoff point for administration of Char-Flo with Sorbitol for gastrointestinal decontamination is 1 to 2 hours post- ingestion. However, in cases where the ingested agent has anticholinergic activity (e.g., tricyclic antidepressants) or can slow the rate of gastric emptying by another mechanism (e.g., pentazocine, meperidine) then use of Char-Flo with Sorbitol beyond 2 hours may still be beneficial.
More about Char-Flo with Sorbitol
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Espanol
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Consumer resources
- Char-Flo with Sorbitol activated
- Char-Flo with Sorbitol
- Other brands: Activated Char-Flo with Sorbitol, Liqui-Char, Optimum Char-Flo with Sorbitol, Insta-Char, More (3) »
Professional resources
- Char-Flo with Sorbitol, Activated (AHFS Monograph)
- More (2) »
Related treatment guides
- Gas
- Gastrointestinal Decontamination
What other drugs will affect Char-Flo with Sorbitol?
Char-Flo with Sorbitol can make it harder for your body to absorb other medicines you take by mouth. Take your this medicine dose at least 1 to 2 hours before or after taking other medicines by mouth.
Other drugs may affect Char-Flo with Sorbitol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Char-Flo with Sorbitol drug interactions (more detail)
Char-Flo with Sorbitol interactions
Leflunomide: Char-Flo with Sorbitol, Activated may decrease serum concentrations of the active metabolite(s) of Leflunomide. Management: Unless using this combination to intentionally enhance leflunomide elimination, consider an alternative to Char-Flo with Sorbitol when possible. Separating drug administration is not likely to be effective at avoiding this interaction. Consider therapy modification
Teriflunomide: Char-Flo with Sorbitol, Activated may decrease the serum concentration of Teriflunomide. Management: Unless using this combination to intentionally enhance teriflunomide elimination, consider an alternative to Char-Flo with Sorbitol when possible. Separating drug administration is not likely to be effective at avoiding this interaction. Consider therapy modification
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Information checked by Dr. Sachin Kumar, MD Pharmacology
