What happens if I overdose Concure?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local, or emergency room immediately. Symptoms may include diarrhea; stomach cramps.
Proper storage of Concure crystals:
Store Concure crystals at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Concure crystals out of the reach of children and away from pets.
Overdose of Concure in details
Signs and Symptoms
There have been no reports of accidental overdosage. In the event of overdosage, it is expected that diarrhea and abdominal cramps would be the major symptoms. Medication should be terminated.
Oral LD50
The acute oral LD50 of the drug is 48.8 mL/kg in mice and greater than 30 mL/kg in rats.
Dialysis
Dialysis data are not available for Concure. Its molecular similarity to sucrose, however, would suggest that it should be dialyzable.
What should I avoid while taking Concure?
Avoid using antacids without your doctor's advice. Use only the specific type of antacid your doctor recommends. Antacids contain different medicines and some types can make it harder for your body to absorb Concure.
Concure warnings
A theoretical hazard may exist for patients being treated with Concure solution who may be required to undergo electrocautery procedures during proctoscopy or colonoscopy. Accumulation of H 2 gas in significant concentration in the presence of an electrical spark may result in an explosive reaction. Although this complication has not been reported with Concure, patients on Concure therapy undergoing such procedures should have a thorough bowel cleansing with a non-fermentable solution. Insufflation of CO2 as an additional safeguard may be pursued but is considered to be a redundant measure.
What should I discuss with my healthcare provider before taking Concure?
Some medical conditions may interact with Concure crystals. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have diabetes, appendix problems, rectal bleeding, or an intestinal blockage
Some MEDICINES MAY INTERACT with Concure crystals. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antacids because they may decrease Concure crystals's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if Concure crystals may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Concure precautions
Patients who are intolerant to lactose should take Concure oral solution with care because it contains lactose.
The dose normally used in constipation should not pose a problem for diabetics. However, the dose used in the treatment of (pre)coma hepaticum is usually much higher and sugar content of Concure should be taken into consideration for diabetics.
Laxatives (of any kind) should be used in children only when deemed absolutely necessary and only under medical supervision. Faecal retention abilities could be disturbed during treatment with Concure oral solution. Take some protective measures, eg, using diapers, for a small child.
Important Information About the Ingredients: Concure may contain small amounts of milk sugar (lactose), galactose, epilactose and fructose. If the patient has an intolerance to some sugars, a physician must be consulted before taking Concure.
Concure contains lactose, galactose and small amounts of fructose. Therefore, patients with the rare hereditary problems of galactose or fructose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take Concure.
Effects on the Ability to Drive or Operate Machinery: Concure oral solution has no or negligible influence on the ability to drive and use machines.
Paediatric Population: Laxatives (of any kind) should be used in children only when deemed absolutely necessary and only under medical supervision. Faecal retention abilities could be disturbed during treatment with Concure oral solution.
What happens if I miss a dose of Concure?
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
References
- DailyMed. "LACTULOSE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DrugBank. "lactulose". http://www.drugbank.ca/drugs/DB00581 (accessed September 17, 2018).
- MeSH. "Gastrointestinal Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
