How do you administer this medicine?
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Pregnancy of Constinil in details
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Constinil is poorly absorbed following oral administration. Use of dietary fiber or bulk-forming laxatives along with increased fluid intake is generally considered first line therapy for treating constipation in pregnant women. Short-term use of Constinil is also considered to be safe/low risk when therapy is needed; however, side effects may limit its use (Cullen, 2007; Mahadevan, 2006; Prather, 2004; Wald, 2003).
Constinil breastfeeding
There are no data on the excretion of Constinil into human milk. While the manufacturer recommends cautious use during lactation, adverse effects in the nursing infant are unlikely given the pharmacology and pharmacokinetics of the drug.
See references
References for pregnancy information
- "Product Information. Chronulac (Constinil)." Hoechst Marion-Roussel Inc, Kansas City, MO.
- "Product Information. Cephulac (Constinil)." Hoechst Marion-Roussel Inc, Kansas City, MO.
References for breastfeeding information
- "Product Information. Cephulac (Constinil)." Hoechst Marion-Roussel Inc, Kansas City, MO.
- "Product Information. Chronulac (Constinil)." Hoechst Marion-Roussel Inc, Kansas City, MO.
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References
- DailyMed. "LACTULOSE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubMed Health. "Lactulose (By mouth): This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
- Human Metabolome Database (HMDB). "Lactulose: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology