Consists of D-panthenol, L-lysine hydrochloride, vitamin B1, vitamin B12, vitamin B2, vitamin B6
Uses of D-panthenol in details
D-Panthenol is a form of Vitamin B5 (pantothenic acid). It is used for treating deficiency of Vitamin B5 in the body. Pantothenic acid is also used alone or in combination with other vitamins for a wide variety of uses. It is also used as an ingredient in skin and hair products, for treating dandruff, gray hair, baldness, treating acne; enhancing immune function; improving athletic performance; tongue infections; headache; insomnia; nerve pain (neuralgia); irritability; allergies; progressive weakness and loss of muscle mass (muscular dystrophy); hyperactivity; carpal tunnel syndrome (numbness, tingling, weakness, and other problems in your hand), depression, chronic fatigue syndrome; congenital hyperthyroidism(overactive thyroid gland from birth), attention deficit-hyperactivity disorder (ADHA), celiac disease (autoimmune disorder related to gluten ingestion).
D-panthenol side effects
Allergic reaction
What is Vitamin B1?
Thiamine is vitamin B1. Thiamine is found in foods such as cereals, whole grains, meat, nuts, beans, and peas. Thiamine is important in the breakdown of carbohydrates from foods into products needed by the body.
Thiamine is used to treat or prevent vitamin B1 deficiency. Thiamine injection is used to treat beriberi, a serious condition caused by prolonged lack of vitamin B1.
Thiamine taken by mouth (oral) is available without a prescription. Injectable thiamine must be given by a healthcare professional.
Thiamine may also be used for purposes not listed in this medication guide.
Vitamin B1 indications
Vitamin B1 deficiency
Vitamin B1 description
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.
Vitamin B1 interactions
Interactions for vitamin B1
Loop Diuretics,
Oral Contraceptives, Stavudine, Tricyclic Antidepressants
Vitamin B1 side effects
Applies to thiamine: capsule, solution, tablet, tablet enteric coated
As well as its needed effects, thiamine (the active ingredient contained in Vitamin B1) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking thiamine, check with your doctor immediately:
Rare - Soon after receiving injection only
- Coughing
- difficulty in swallowing
- hives
- itching of skin
- swelling of face, lips, or eyelids
- wheezing or difficulty in breathing
Vitamin B1 contraindications
Contraindications for vitamin B1
Hypersensitivity to vitamin B1 or any component of a product containing vitamin B1.
What is Vitamin B12?
Cyanocobalamin is a man-made form of vitamin B12. Vitamin B12 is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.
Cyanocobalamin is used to treat vitamin B12 deficiency in people with pernicious anemia and other conditions.
Cyanocobalamin may also be used for purposes not listed in this medication guide.
Vitamin B12 indications
Pernicious anemia, both uncomplicated and accompanied by nervous system involvement.
Dietary deficiency of Vitamin B12, occurring in strict vegetarians and in their breast-fed infants. (Isolated vitamin B12 deficiency is very rare).
Malabsorption of vitamin B12, resulting from structural or functional damage to the stomach, where intrinsic factor is secreted or to the ileum, where intrinsic factor facilitates vitamin B12 absorption. These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than vitamin B12 deficiency.
Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces vitamin B12 deficiency.
Structural lesions leading to vitamin B12 deficiency include regional ileitis, ileal resections, malignancies, etc.
Competition for Vitamin B12 by intestinal parasites or bacteria.
The fish tapeworm (Diphyilobothrium latum) absorbs huge quantities of vitamin B12 and infested patients often have associated gastric atrophy. The blind-loop syndrome may produce deficiency of Vitamin B12 or folate.
Inadequate utilization of vitamin B12. This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.
For the Schilling Test.
Vitamin B12 description
Vitamin B12 (commonly known as Vitamin B12) is the most chemically complex of all the vitamins. Vitamin B12's structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Vitamin B12 cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Vitamin B12 is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products.
Vitamin B12 dosage
Vitamin B12 is used as injections SC, IV, IM, intralumbar, and also oral. With anemia associated with vitamin B12 deficiency is introduced on 100-200 mcg in 2 days. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. In acute post-hemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. When aplastic anemia (especially in children) - 100 micrograms before clinical improvement. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days.
In diseases of the central and peripheral nervous system and neurological diseases with a pain syndrome is administered in increasing doses - 200-500 mcg, with the improvement in the state - 100 mcg / day. The course of treatment with Vitamin B12 is 2 weeks. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days.
When hepatitis and cirrhosis - 30-60 mcg / day or 100 mg every other day for 25-40 days.
Dystrophy in young children, Down syndrome and cerebral palsy - by 15-30 mcg every other day.
When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms.
In radiation sickness, diabetic neuropathy, sprue - by 60-100 mcg daily for 20-30 days.
When deficiency of vitamin B12 to prevent - IV or IM for 1 mg 1 time a month; for treatment - IV or IM for 1 mg daily for 1-2 weeks, the maintenance dose is 1-2 mg IV or IM from 1 per week, up to 1 per month. Duration of treatment is determined individually.
Vitamin B12 interactions
In an application of Vitamin B12 Atlantic Laboratories with hormonal contraceptives for oral administration may decrease the concentration of cyanocobalamin in plasma.
In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut.
In an Vitamin B12 Atlantic Laboratories application with neomycin, aminosalicylic acid, colchicine, cimetidine, ranitidine, drugs potassium decreased cyanocobalamin absorption from the gut.
Cyanocobalamin may exacerbate allergic reactions caused by thiamine.
When parenteral application of chloramphenicol may decrease the hematopoietic effects of cyanocobalamin with anemia.
Vitamin B12 side effects
See also:
What are the possible side effects of Vitamin B12?
Applies to cyanocobalamin: intramuscular solution
Other dosage forms:
- nasal gel/jelly, nasal spray
As well as its needed effects, cyanocobalamin (the active ingredient contained in Vitamin B12) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking cyanocobalamin, check with your doctor or nurse immediately:
Incidence not known:
- Abdominal or stomach pain
- bleeding from the gums or nose
- blue lips and fingernails
- chest pain
- cough
- coughing that sometimes produces a pink frothy sputum
- decreased urine output
- difficult, fast, noisy breathing, sometimes with wheezing
- difficulty with swallowing
- dilated neck veins
- dizziness
- extreme fatigue
- eye pain
- fast heartbeat
- headache
- hives, itching, or skin rash
- increased sweating
- irregular breathing
- irregular heartbeat
- pale skin
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- ringing in the ears
- swelling of the face, fingers, feet, or lower legs
- tightness in the chest
- unusual tiredness or weakness
- weight gain
Minor Side Effects
Some cyanocobalamin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
Incidence not known:
- Diarrhea
- skin rash with a general disease
Vitamin B12 contraindications
Hypersensitivity to the components of the formula. History of allergy to the cobalamins (vitamin B12 and similar substances). Malignant tumors. By stimulating the growth of tissues, the Cobamamide could increase the high rate of cell multiplication. Sensitivity to cobalt. History of allergies to cobalamin (vitamin B12 and related substances).
- Malignant tumor: Due to the action of vitamin B12 on the growth of tissue cell multiplication rate high, the risk of exacerbation should be taken into account.
- Children under 6 years because of the dosage form
What is Vitamin B2?
Riboflavin is vitamin B2. Vitamins are naturally occurring substances necessary for many processes in the body. Riboflavin is important in the maintenance of many tissues of the body.
Riboflavin is used to prevent and to treat deficiencies of riboflavin.
Riboflavin may also be used for other purposes not listed in this medication guide.
Vitamin B2 indications
vitamin b2 deficiency
Uses of Vitamin B2 in details
Vitamin B2 (riboflavin) supplementation is used to prevent and treat riboflavin deficiency. Vitamin B2 may prevent migraine headaches at high doses and be useful for prevention of eye conditions such as cataract, glaucoma and tired eyes (fatigue). Vitamin B2 is also used for boosting of immune system, and maintenance of healthy hair, skin, nails and mucous membranes.
Vitamin B2 description
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide.
Vitamin B2 interactions
Interactions for vitamin B2
Alcohol - impairs the intestinal absorption of riboflavi
Antidepressants (tricyclics or phenothiazines) - requirements for riboflavin may be increased in patients receiving these medications
Probenecid - concurrent use decreases gastrointestinal absorption of riboflavin; requirements for riboflavin may be increased in patients receiving probenecid.
Vitamin B2 side effects
Genitourinary
Yellow-orange discoloration of urine.
Vitamin B2 contraindications
None well documented.
What is Vitamin B6?
Pyridoxine is vitamin B6. Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 is important for many processes in the body.
Pyridoxine is used to treat or prevent vitamin B6 deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies.
Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.
Pyridoxine may also be used for purposes not listed in this medication guide.
Vitamin B6 indications
* Sideroblastic anaemia
* Treatment and prophylaxis of vitamin B6 deficiency states
How should I use Vitamin B6?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Pyridoxine tablets are taken by mouth. Injectable pyridoxine is injected into a muscle or into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
The recommended dietary allowance of pyridoxine increases with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly "Recommended Daily Allowances") listings for more information.
Pyridoxine is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat or avoid to help control your condition.
Store at room temperature away from moisture and heat.
Uses of Vitamin B6 in details
It is used for the treatment and prevention of vitamin B6 deficiency. It is important for the breakdown of protein, fats, and carbohydrates from foods.
Vitamin B6 description
The 4-methanol form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).
Vitamin B6 interactions
Interactions for vitamin B6
Amiodarone: Concomitant use of vitamin B6 and amiodarone may enhance amiodarone-induced photosensitivity reactions. Doses of vitamin B6 greater than 5-10 milligrams/day should be avoided by those taking amiodarone Carbamazepine: Chronic use of carbamazepine may result in a significant decrease in plasma pyridoxal 5-phosphate levels Cycloserine: Cycloserine may react with pyridoxal 5-phosphate to form a metabolically inactive oxime, which may result in a functional vitamin B6 deficiency Ethionamide: The use of ethionamide may increase vitamin B6 requirements Fosphenytoin: High doses of vitamin B6 may lower plasma levels of phenytoin. Fosphenytoin is a prodrug of phenytoin Hydralazine: The use of hydralazine may increase vitamin B6 requirements Isoniazid: (isonicotinic acid, INH). Isoniazid reacts with pyridoxal 5-phosphate to form a metabolically inactive hydrazone, which may result in functional vitamin B6 deficiency Levodopa: Concomitant use of levodopa and vitamin B6 in doses of 5 milligrams or more daily may reverse the therapeutic effects of levodopa. Vitamin B6 does not reverse the therapeutic effects of levodopa if levodopa is taken concurrently with the levodopa decarboxylase inhibitor carbidopa. Levodopa is typically administered as a combination product with carbidopa
Oral contraceptives: The use of oral contraceptives may increase vitamin B6 requirements. This was more the case with the older oral contraceptive agents with high-dose estrogen/progestin. It appears to be less the case with the newer low-dose estrogen/progestin products Penicillamine: Penicillamine may react with pyridoxal 5-phosphate to form a metabolically inactive thiazolidine, which may result in a functional vitamin B6 deficiency Phenelzine: Phenelzine may react with pyridoxal 5-phosphate to yield a metabolically inactive hydrazone compound Phenobarbital: High doses of vitamin B6 may lower plasma levels of phenobarbital Phenytoin: High doses of vitamin B6 may lower plasma levels of phenytoin Theophylline: Theophylline may react with pyridoxal 5-phosphate leading to low plasma levels of the coenzyme. This may increase the risk of theophylline-induced seizures Valproic acid: Chronic use of valproic acid may result in a significant decrease in plasma pyridoxal 5-phosphate levels.
Vitamin B6 side effects
Applies to pyridoxine: capsule, injectable, solution, tablet, tablet enteric coated, tablet extended release
As well as its needed effects, pyridoxine (the active ingredient contained in Vitamin B6) may cause unwanted side effects that require medical attention.
Severity: Moderate
If any of the following side effects occur while taking pyridoxine, check with your doctor or nurse as soon as possible:
With large doses
- Clumsiness
- numbness of hands or feet
Vitamin B6 contraindications
Contraindications for vitamin B6
Vitamin B6 is contraindicated in those hypersensitive to any component of a vitamin B6-containing product.
Active ingredient matches for D-panthenol/L-lysine hydrochloride/vitamin B1/vitamin B12/vitamin B2/vitamin B6:
D-panthenol/L-lysine hydrochloride/vitamin B1/vitamin B12/vitamin B2/vitamin B6
References
- PubChem. "L-lysine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "L-lysine". http://www.drugbank.ca/drugs/DB00123 (accessed September 17, 2018).
- MeSH. "MeSH Tree: MeSH (Medical Subject Headings) is the NLM controlled vocabulary thesaurus used for indexing articles for PubMed.". http://www.nlm.nih.gov/mesh/meshhome... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for D-panthenol/L-lysine hydrochloride/vitamin B1/vitamin B12/vitamin B2/vitamin B6 are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking D-panthenol/L-lysine hydrochloride/vitamin B1/vitamin B12/vitamin B2/vitamin B6. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
