Derihaler 100 indications
Inhaler: Provides short-acting (4-6 hrs) bronchodilation with fast onset (within 5 min) in reversible airways obstruction.
It is particularly suitable for the relief and prevention of asthma symptoms. It should be used to relieve symptoms when they occur, and to prevent them in those circumstances recognised by the patient to precipitate an asthma attack (eg, before exercise or unavoidable allergen exposure).
Accuhaler: Management of asthma, bronchospasm and/or reversible airways obstruction.
Inhaler/Accuhaler: Relief and prevention of asthma symptoms. It should be used to relieve symptoms when they occur and to prevent them in those circumstances recognised by the patient to precipitate an asthma attack (eg, before exercise or unavoidable allergen exposure).
It is particularly valuable as a relief medication in mild, moderate or severe asthma, provided that reliance on it does not delay the introduction and use of regular inhaled corticosteroid therapy.
Nebule: Routine management of chronic bronchospasm unresponsive to conventional therapy and in the treatment of acute severe asthma (eg, status asthmaticus).
Injection/IV Infusion: Relief of severe bronchospasm associated with asthma or bronchitis and for the treatment of status asthmaticus. Short-term management of uncomplicated premature labour; to arrest labour between 22 and 37 weeks of gestation in patients with no medical or obstetric contraindication to tocolytic therapy.
Derihaler 100 description
MDI: Each actuation delivers Derihaler 100 100 mcg. It is a suspension aerosol for oral inhalation supplied in a pressurized container.
Derihaler 100 dosage
Derihaler 100 for oral use as a means of extending the broncho adults and children over 12 years - 2.4 mg 3-4 times / day; if necessary, the dose may be increased to 8 mg 4 times / day. Children aged 6-12 years - 2 mg 3-4 times / day; children 2-6 years - 1-2 mg 3 times / day.
Derihaler 100 for inhalation use dose depends on the applied dosage form, frequency of use depends on the testimony and the clinical situation.
As a tocolytic agent used as IV infusion in dose of 1-2 mg.
Derihaler 100 interactions
Ventolin and nonselective β-blocking drugs eg, propranolol, should not usually be prescribed together. Ventolin is not contraindicated in patients under treatment with monoamine oxidase inhibitors (MAOIs).
IV Infusion: Halogenated Anaesthetics: Owing to the additional antihypertensive effect, there is increased uterine inertia with risk of haemorrhage; in addition, serious ventricular rhythm disorders due to increased cardiac reactivity, have been reported on interaction with halogenated anaesthetics. Treatment should be discontinued, whenever possible, at least 6 hrs before any scheduled anaesthesia with halogenated anaesthetics.
Corticosteroids: Systemic corticosteroids are frequently given during premature labour to enhance foetal lung development. There have been reports of pulmonary oedema in women concomitantly administered with β-agonists and corticosteroids.
Corticosteroids are known to increase blood glucose and can deplete serum potassium, therefore concomitant administration should be undertaken with caution with continuous patient monitoring owing to the increased risk of hyperglycaemia and hypokalaemia.
Antidiabetics: The administration of β-agonists is associated with a rise of blood glucose, which can be interpreted as an attenuation of anti-diabetic therapy; therefore individual antidiabetic therapy may need to be adjusted.
Potassium Depleting Agents: Owing to the hypokalaemic effect of β-agonists, concurrent administration of serum potassium depleting agents known to exacerbate the risk of hypokalaemia eg, diuretics, digoxin, methyl xanthines and corticosteroids, should be administered cautiously after careful evaluation of the benefits and risks with special regard to the increased risk of cardiac arrhythmias arising as a result of hypokalaemia.
Derihaler 100 side effects
Tremors (particularly the hands), palpitations, tachycardia, hypertension, headache, nervousness, peripheral vasodilation, and rarely muscle cramps have been observed after administration of salbutamol aerosol inhalation. Potentially serious hypokalemia has also been reported.
Cases of urticaria, angioedema, rash, anaphylaxis, paradoxical bronchospasm, epistaxis, cough, hoarseness, oropharyngeal edema, heartburn, hypotension, arrhythmias (including atrial fibrillation, supraventricular tachycardia and extrasystoles), and collapse have also been noted after the use of inhaled salbutamol.
Salbutamol can also cause angina, vomiting, vertigo, CNS stimulation, hyperactivity (in children), unusual taste, and dryness or irritation of the oropharynx.
Derihaler 100 contraindications
Patients with a history of hypersensitivity to Derihaler 100 or to any of the components of Ventolin.
Accuhaler: Although IV salbutamol and occasional salbutamol tablets are used in the management of premature labour uncomplicated by conditions eg, placenta praevia, ante-partum haemorrhage or toxaemia of pregnancy, inhaled salbutamol preparations are not appropriate for managing premature labour. Salbutamol presentations should not be used for threatened abortion.
Ventolin accuhaler are contraindicated in patients with severe milk-protein allergy.
IV Infusion: Ventolin solution for IV infusion is contraindicated in the following conditions: Any condition at a gestational age <22 weeks; as a tocolytic agent in patients with preexisting ischaemic heart disease or those patients with significant risk factors for ischaemic heart disease; threatened abortion during the 1st and 2nd trimester; any condition of the mother or foetus in which prolongation of the pregnancy is hazardous eg, severe toxaemia, intrauterine infection, vaginal bleeding resulting from placenta praevia, eclampsia or severe preeclampsia, placental abruption or cord compression; intrauterine foetal death, known lethal congenital or lethal chromosomal malformation.
Ventolin solution for IV infusion is also contraindicated in any preexisting medical conditions with which a betamimetic would have an untoward effect eg, pulmonary hypertension and cardiac disorders eg, hypertrophic obstructive cardiomyopathy or any type of obstruction of the left ventricular outflow tract eg, aortic stenosis.
Active ingredient matches for Derihaler 100:
Salbutamol sulfate in Philippines.
| Unit description / dosage (Manufacturer) | Price, USD |
| Derihaler 100 MDI 100 mcg 1's (Zydus Healthcare Phils) | $ 4.67 |
List of Derihaler 100 substitutes (brand and generic names): | |
| Apotex NZ Ltd | |
| Asmacaire Solution For Inhalation (Philippines) | |
| Asmacaire Syrup (Philippines) | |
| Asmacaire Syrup 2 mg/5 mL 60 mL x 1's (Elin) | $ 1.58 |
| Asmalin MDI (Philippines) | |
| Asmalin MDI 100 mcg/dose / CFC/ODS Free 200 dose x 1's (Pediatrica) | $ 7.43 |
| Asmalin Pulmocap (Philippines) | |
| Asmalin Pulmocap 200 mcg x 100's | $ 8.28 |
| Asmigen (New Zealand) | |
| Asthalin CFC-Free (Thailand) | |
| Broncolin Expectorant (Malaysia) | |
| Broncolin Expectorant / raspberry flavour 90 mL | |
| Cybutol 200 (Vietnam) | |
| Cybutol 200 200 mcg x 10 Blister x 10 Tablet | |
| DLI-Salbutamol (Philippines) | |
| Efamed/Efamed Plus (Philippines) | |
| Efamed Plus FC tab 100's (Medhaus) | |
| Efamed Plus syr 60 mL x 1's (Medhaus) | |
| Efamed syr 2 mg/5 mL 60 mL x 1's (Medhaus) | |
| Glisend (Indonesia) | |
| Hivent/Hivent DS (Philippines) | |
| Hivent DS nebuliser soln 2 mg/mL 2.5 mL x 1's (Euro-Med) | $ 0.67 |
| Hivent nebuliser soln 1 mg/mL 2.5 mL x 1's (Euro-Med) | $ 0.56 |
| Meventil (Philippines) | |
| Meventil 2 mg/5 mL x 120 mL | $ 2.00 |
| Pädiamol (Germany) | |
| Solution; Inhalation; Albuterol Sulfate (Padia) | |
| Phil Pharmawealth/Cipla Salbutamol Sulfate (Philippines) | |
| Provexel NS (Philippines) | |
| Respax Delta West (Vietnam) | |
| Respax Delta West 5 mg/1 mL x 30 mL x 20 Bottle | |
| Respax Delta West 5 mg/1 mL x 10 mL x 48 Bottle | |
| Respax Delta West 1 mg/1 mL x 2, 5 mL x 30 tube | |
| Respax Delta West 2 mg/1 mL x 2, 5 mL x 30 tube | |
| Salbuflo (Philippines) | |
| Salbuflo 100 mcg/1 dose x 200 doses | |
| Salbuhaler (Philippines) | |
| Salbuhaler MDI 100 mcg/dose 14 mL x 1's (Sandoz) | |
| Salbutamol Sulfate | |
| Salbutamol Xepa-Soul (Singapore) | |
| Salbutamol Xepa-Soul 2 mg x 1000's | $ 15.00 |
| Salbutamol Xepa-Soul 2 mg/5 mL x 1 L x 1's | $ 8.20 |
| Salbutamol Yung Shin (Singapore) | |
| Salbutamol Yung Shin 2 mg/5 mL x 60 mL x 12's | |
| Salbutamol Yung Shin 2 mg/5 mL x 4 L x 4's | |
| Synvent HFA 100 欣氣寧定量 (Hongkong) | |
| Synvent HFA 100 inhaler 100 mcg/dose / / 200 doses 100 mL x 1's (Synmosa) | |
| Ven-o-sal (Turkey) | |
| Ventolin Injection (Thailand) | |
| Ventolin Tablet/Sirup (Indonesia) | |
| Ventolin 喘樂寧 (Hongkong) | |
| Ventolin accuhaler 200 mcg/actuation 60 actuation x 1's (GlaxoSmithKline) | |
| Ventolin infusion 5 mg/5 mL 10 x 1's (GlaxoSmithKline) | |
| Ventolin inhaler 100 mcg/actuation / CFC-free 200 actuation x 1's (GlaxoSmithKline) | |
| Ventolin nebules 2.5 mg/2.5 mL 20 x 1's (GlaxoSmithKline) | |
| Vimonzil (Philippines) | |
| Vimonzil 2 mg/5 mL x 60 mL | |
See 44 substitutes for Derihaler 100 | |
References
- DailyMed. "ALBUTEROL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Salbutamol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Salbutamol". http://www.drugbank.ca/drugs/DB01001 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Derihaler 100 are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Derihaler 100. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet2 consumers reported age
| Users | % | ||
|---|---|---|---|
| 16-29 | 1 | 50.0% | |
| 30-45 | 1 | 50.0% | |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
