Dosage of Dicicloverina [Inn-Spanish] in details
Dosage must be adjusted to individual patients needs.
Oral Dosage And Administration In Adults
The recommended initial dose is 20 mg four times a day. After one week treatment with the initial dose, the dose may be increased to 40 mg four times a day unless side effects limit dosage escalation. If efficacy is not achieved within 2 weeks or side effects require doses below 80 mg per day, the drug should be discontinued. Documented safety data are not available for doses above 80 mg daily for periods longer than 2 weeks.
Intramuscular Dosage And Administration In Adults
Dicicloverina [Inn-Spanish]
Intramuscular Injection must be administered via
intramuscular route only. Do not administer by an other route. The recommended intramuscular dose is 10 mg to 20 mg four times a day.The intramuscular injection is to be used only for 1 or 2 days when the patient cannot take oral medication.
Intramuscular injection is about twice as bioavailable as oral dosage forms.
Preparation For
Intramuscular Administration
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
Aspirate the syringe before injecting to avoid intravascular injection, since thrombosis may occur if the drug is inadvertently injected intravascularly.
How supplied
Dosage Forms And Strengths
- Dicicloverina [Inn-Spanish] 10 mg capsules: blue, imprinted Dicicloverina [Inn-Spanish] 10
- Dicicloverina [Inn-Spanish] 20 mg tablets: compressed, light blue, round, debossed Dicicloverina [Inn-Spanish] 20
- Dicicloverina [Inn-Spanish] injection 20 mg/2 mL (10 mg/mL)
Storage And Handling
Dicicloverina [Inn-Spanish] Capsules
10 mg blue capsules, imprinted Dicicloverina [Inn-Spanish] 10, supplied in bottles of 100. Store at room temperature, preferably below 86°F (30°C).
NDC number: 58914-012-10.
Dicicloverina [Inn-Spanish] Tablets
20 mg compressed, light blue, round tablets, debossed Dicicloverina [Inn-Spanish] 20, supplied in bottles of 100. To prevent fading, avoid exposure to direct sunlight. Store at room temperature, preferably below 86°F (30°C).
NDC 58914-013-10.
Dicicloverina [Inn-Spanish] Injection
20 mg/2 mL (10 mg/mL) injection supplied in boxes of five 20 mg/2 mL ampules (10 mg/mL). Store at room temperature, preferably below 86°F (30°C). Protect from freezing.
NDC 58914-080-52.
Manufactured for: Aptalis Pharma US, Inc. 100 Somerset Corporate Boulevard, Bridgewater, NJ 08807 USA. Revised: June 2013
What other drugs will affect Dicicloverina [Inn-Spanish]?
Using Dicicloverina [Inn-Spanish] with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your current medicines. Many drugs can affect Dicicloverina [Inn-Spanish], especially:
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bronchodilator asthma medication;
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cold or allergy medicine (Benadryl and others);
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glaucoma medication;
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heart medication;
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medicine to treat depression, anxiety, mood disorders, or mental illness;
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medicine to treat overactive bladder;
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medicine to treat Parkinson's disease; or
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medicine to treat stomach problems, motion sickness, or irritable bowel syndrome.
This list is not complete and many other drugs may affect Dicicloverina [Inn-Spanish]. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Dicicloverina [Inn-Spanish] drug interactions (more detail)
Does Dicicloverina [Inn-Spanish] interact with my other drugs?
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Dicicloverina [Inn-Spanish] interactions
Antiglaucoma Agents
Anticholinergics antagonize the effects of antiglaucoma agents. Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corticosteroids. Use of Dicicloverina [Inn-Spanish] in patients with glaucoma is not recommended.
Other Drugs With Anticholinergic Activity
The following agents may increase certain actions or side effects of anticholinergic drugs including Dicicloverina [Inn-Spanish]: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity.
Other Gastrointestinal Motility Drugs
Interaction with other gastrointestinal motility drugs may antagonize the effects of drugs that alter gastrointestinal motility, such as metoclopramide.
Effect Of Antacids
Because antacids may interfere with the absorption of anticholinergic agents including Dicicloverina [Inn-Spanish], simultaneous use of these drugs should be avoided.
Effect On Absorption Of Other Drugs
Anticholinergic agents may affect gastrointestinal absorption of various drugs by affecting gastrointestinal motility, such as slowly dissolving dosage forms of digoxin; increased serum digoxin concentration may result.
Effect On Gastric Acid Secretion
The inhibiting effects of anticholinergic drugs on gastric hydrochloric acid secretion are antagonized by agents used to treat achlorhydria and those used to test gastric secretion.
References
- FDA/SPL Indexing Data. "4KV4X8IF6V: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
- MeSH. "Parasympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
- European Chemicals Agency - ECHA. "Dicycloverine: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Dicicloverina [Inn-Spanish] are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dicicloverina [Inn-Spanish]. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported frequency of use
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Information checked by Dr. Sachin Kumar, MD Pharmacology
