What are the possible side effects of Dopasys?
Get emergency medical help if you have any of these signs of an allergic reaction to Dopasys: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you suffer a serious side effect from Dopasys such as:
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chest pain;
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fast, slow, or pounding heartbeats;
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painful or difficult urination, blood in your urine;
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weakness, confusion, swelling in your feet or ankles, urinating less than usual or not at all;
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weak or shallow breathing;
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feeling like you might pass out, even while lying down;
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burning, pain, or swelling around the IV needle;
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cold feeling, numbness, or blue-colored appearance in your hands or feet; or
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darkening or skin changes in your hands or feet.
Less serious Dopasys side effects may include:
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headache;
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feeling anxious;
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nausea, vomiting; or
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chills, goosebumps.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Side effects of Dopasys in details
Common Reactions: Adverse eactions have been observed in 19% of patients during clinical evaluation; however, only half of these were attributed to Dopasys. Treatment was terminated in 5% of all patients due to adverse reactions.
Cardiovascular: Ectopic beats, tachycardia, anginal pain, palpitation, hypotension, vasoconstriction.
Gastrointestinal: Nausea, vomiting.
Nervous system: Headache.
Respiratory: Dyspnea.
Less Common Reactions: Biochemical Abnormalities: Azotemia.
Cardiovascular: Aberrant ventricular conduction, bradycardia, widened QRS complex, hypertension. Gangrene of the feet has occurred in a few patients with preexisting vascular disease. A few cases of peripheral cyanosis have been reported in patients receiving Dopasys.
Nervous System: Piloerection, anxiety.
Serious or Life-Threatening Reactions: Gangrene of the feet has occurred following doses of 10-14 mcg/kg/min and higher in a few patients with preexisting vascular disease.
Fatal ventricular arrhythmias have been reported on rare occasions. Extravasation of Dopasys may cause necrosis and sloughing of surrounding tissue.
What is the most important information I should know about Dopasys?
- Some of these products contain sulfites, which can cause allergic reactions in certain individuals (eg, asthma patients). If you have previously had allergic reactions to sulfites, contact your pharmacist to determine if the product you are taking contains sulfites.
- LAB TESTS, including urine output, heart function, blood pressure, and thyroid tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
- PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Dopasys, discuss with your doctor the benefits and risks of using Dopasys during pregnancy. It is unknown if Dopasys is excreted in breast milk. If you are or will be breast-feeding while you are using Dopasys, check with your doctor or pharmacist to discuss the risks to your baby.
Dopasys contraindications
If possible before you receive Dopasys injection, tell your caregivers if you have pheochromocytoma (tumor of the adrenal gland).
Also tell your caregivers if you have hardened arteries, circulation problems, diabetes, frostbite, Buergers disease, asthma, sulfite allergy, or a history of blood clots.
Tell your doctor about all the prescription and over-the-counter medications you use, especially if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 21 days.
In an emergency situation it may not be possible before you are treated to tell your caregivers about your health conditions or if you are pregnant or breast feeding. Make sure any doctor caring for you afterward knows that you have received this medication.
References
- DTP/NCI. "dopamine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
- European Chemicals Agency - ECHA. "dopamine: The European Chemicals Agency (ECHA) is an agency of the European Union which is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.". https://echa.europa.eu/ (accessed September 17, 2018).
- HSDB. "DOPAMINE". https://toxnet.nlm.nih.gov/cgi-bin/s... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Dopasys are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dopasys. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported side effects
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Information checked by Dr. Sachin Kumar, MD Pharmacology