What happens if I overdose Ethambutol Strides Arcolab?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.
Proper storage of Ethambutol Strides Arcolab:
Store Ethambutol Strides Arcolab at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Ethambutol Strides Arcolab out of the reach of children and away from pets.
Overdose of Ethambutol Strides Arcolab in details
No information provided.
What should I avoid while taking Ethambutol Strides Arcolab?
Avoid taking an antacid containing aluminum hydroxide (Alternagel, Maalox, Mi-Acid, Mylanta, Rulox) within 4 hours after you take Ethambutol Strides Arcolab. Some antacids can make it harder for your body to absorb Ethambutol Strides Arcolab.
Ethambutol Strides Arcolab warnings
Ethambutol Strides Arcolab hydrochloride may produce decreases in visual acuity which appear to be due to optic neuritis. This effect may be related to dose and duration of treatment. This effect is generally reversible when administration of the drug is discontinued promptly. However, irreversible blindness has been reported..
Liver toxicities including fatalities have been reported. Baseline and periodic assessment of hepatic function should be performed.
What should I discuss with my healthcare provider before taking Ethambutol Strides Arcolab?
You should not use Ethambutol Strides Arcolab if you are allergic to it. You may not be able to take Ethambutol Strides Arcolab if you have an eye condition called optic neuritis (inflammation of nerve fibers behind your eyes). Your doctor will decide if this treatment is right for if you have an eye disorder.
Ethambutol Strides Arcolab can cause vision problems that may be a sign that you should stop taking the medicine. You may not be able to take Ethambutol Strides Arcolab if you cannot recognize or report any changes in your vision. Young children or debilitated patients may not be able to tell someone about vision problems.
To make sure Ethambutol Strides Arcolab is safe for you, tell your doctor if you have:
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inflammatory eye disorders such as uveitis or iritis;
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eye problems caused by diabetes;
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cataracts;
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liver disease;
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kidney disease; or
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gout.
FDA pregnancy category C. It is not known whether Ethambutol Strides Arcolab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
Ethambutol Strides Arcolab can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Ethambutol Strides Arcolab should not be given to a child younger than 13 years old.
Ethambutol Strides Arcolab precautions
Ethambutol Strides Arcolab Ethambutol Strides Arcolab hydrochloride is not recommended for use in pediatric patients under thirteen years of age since safe conditions for use have not been established.
Patients with decreased renal function need the dosage reduced as determined by serum levels of Ethambutol Strides Arcolab, since the main path of excretion of this drug is by the kidneys.
Because this drug may have adverse effects on vision, physical examination should include ophthalmoscopy, finger perimetry and testing of color discrimination. In patients with visual defects such as cataracts, recurrent inflammatory conditions of the eye, optic neuritis, and diabetic retinopathy, the evaluation of changes in visual acuity is more difficult, and care should be taken to be sure the variations in vision are not due to the underlying disease conditions. In such patients, consideration should be given to relationship between benefits expected and possible visual deterioration since evaluation of visual changes is difficult. (For recommended procedures, see next paragraphs under ADVERSE REACTIONS).
As with any potent drug, baseline and periodic assessment of organ system functions, including renal, hepatic, and hematopoietic, should be performed.
Drug Interactions:
The results of a study of coadministration of Ethambutol Strides Arcolab (50mg/kg) with an aluminum hydroxide containing antacid to 13 patients with tuberculosis showed a reduction of mean serum concentrations and urinary excretion of Ethambutol Strides Arcolab of approximately 20% and 13%, respectively, suggesting that the oral absorption of Ethambutol Strides Arcolab may be reduced by these antacid products. It is recommended to avoid concurrent administration of Ethambutol Strides Arcolab with aluminum hydroxide containing antacids for at least 4 hours following Ethambutol Strides Arcolab administration.
Pregnancy:
Teratogenic Effects: Pregnancy Category C.
There are no adequate and well-controlled studies in pregnant women. There are reports of ophthalmic abnormalities occurring in
infants born to women on antituberculous therapy that included Ethambutol Strides Arcolab. Ethambutol Strides Arcolab should be used during pregnancy
only if the benefit justifies the potential risk to the fetus.
Ethambutol Strides Arcolab has been shown to be teratogenic in pregnant mice and rabbits when given in high doses. When pregnant mice or
rabbits were treated with high doses of Ethambutol Strides Arcolab hydrochloride, fetal mortality was slightly but not significantly (P>0.05) increased.
Female rats treated with Ethambutol Strides Arcolab hydrochloride displayed slight but insignificant (P>0.05) decreases in fertility and litter size.
In fetuses born of mice treated with high doses of Ethambutol Strides Arcolab during pregnancy, a low incidence of cleft palate, exencephaly
and abnormality of the vertebral column were observed. Minor abnormalities of the cervical vertebra were seen in the newborn of
rats treated with high doses of Ethambutol Strides Arcolab hydrochloride during pregnancy. Rabbits receiving high doses of Ethambutol Strides Arcolab during
pregnancy gave birth to two fetuses with monophthalmia, one with a shortened right forearm accompanied by bilateral wrist-joint
contracture and one with hare lip and cleft palate.
Nursing Mothers:
Ethambutol Strides Arcolab is excreted into breast milk. The use of Ethambutol Strides Arcolab should be considered only if the expected benefit to the mother outweighs the potential risk to the infant.
Pediatric Use:
Ethambutol Strides Arcolab (Ethambutol Strides Arcolab hydrochloride) is not recommended for use in pediatric patients under thirteen years of age since safe conditions for use have not been established.
Geriatric Use:
There are limited data on the use of Ethambutol Strides Arcolab in the elderly. One study of 101 patients, 65 years and older, on multiple drug antituberculosis regimens included 94 patients on Ethambutol Strides Arcolab. No differences in safety or tolerability were observed in these patients compared with that reported in adults in general. Other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.
What happens if I miss a dose of Ethambutol Strides Arcolab?
Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.
References
- DailyMed. "ETHAMBUTOL HYDROCHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DrugBank. "ethambutol". http://www.drugbank.ca/drugs/DB00330 (accessed September 17, 2018).
- MeSH. "Antitubercular Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
