Feroglobin Capsules Dosage

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Consists of Copper, Folic Acid, Iron, Vitamin B, Zinc

Dosage of Copper (Feroglobin Capsules) in details

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Copper (Feroglobin Capsules) Dosage

Generic name: Copper (Feroglobin Capsules) 313.4mg

Dosage form: intrauterine device

Medically reviewed by Drugs.com. Last updated on Sep 1, 2019.

Important Dosage and Administration Instructions

Timing of Insertion

Refer to Table 1 for recommended timing of Copper (Feroglobin Capsules) insertion.

Table 1: Recommended Timing of Copper (Feroglobin Capsules) Insertion
Clinical Situation Recommended Timing of Copper (Feroglobin Capsules) Insertion
1. Start Copper (Feroglobin Capsules) in females not currently using contraception At any time during the menstrual cycle.
2. Switch to Copper (Feroglobin Capsules) from an oral, transdermal, or vaginal form of hormonal contraception or an injectable progestin contraceptive At any time during the menstrual cycle; discontinue the previous method.
3. Switch to Copper (Feroglobin Capsules) from a contraceptive implant or other intrauterine system Same day the implant or IUS is removed (insert at any time during the menstrual cycle).
4. Insert Copper (Feroglobin Capsules) after abortion or miscarriage Immediately after abortion, although immediate placement has a slightly higher risk of expulsion than
placement at other times. Insertion after second trimester abortion is associated with a higher risk of expulsion than insertion after a first trimester abortion.
5. Insert Copper (Feroglobin Capsules) after Childbirth May insert immediately postpartum.
Insertion before uterine involution is complete, which may not occur until the second postpartum month, has been associated with increased risk of expulsion.
There appears to be an increased risk of perforation in lactating women.

Preparation Instruction

Before insertion:

Figure 1: Copper (Feroglobin Capsules) Intrauterine System (IUS) with Insertion Tube and Solid White Rod

Insertion Procedure

Figure 2: Inserting Tips of T-Arms of Paraguard into Insertion Tube

Figure 3: Bending T-Arms of Paraguard While in Sterile Packaging

Figure 4: Inserting Tips of T-Arms of Paraguard into Insertion Tube While in Sterile Packaging

Figure 5: Insertion Tube with Paraguard in Uterus

Figure 6: Release of T-Arms of Paraguard in Uterus

Figure 7: Placement of Paraguard in Fundus of Uterus

Figure 8: Withdraw Solid White Rod from Uterus

Figure 9: Appropriate Paraguard Placement in Uterus

If you suspect that Copper (Feroglobin Capsules) is not in the correct position, check placement (with ultrasound, if necessary). If Copper (Feroglobin Capsules) is not positioned completely within the uterus, remove it and replace it with a new Copper (Feroglobin Capsules). Do not reinsert an expelled or partially expelled Copper (Feroglobin Capsules).

Postplacement Management of Paraguard

Following placement:

Do not reinsert a used Copper (Feroglobin Capsules).

2.6 Removal of Paraguard

Timing of Removal

Removal Instructions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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Copper (Feroglobin Capsules) interactions

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Ascorbic Acid: Copper (Feroglobin Capsules) may decrease the serum concentration of Ascorbic Acid. Management: To minimize the risk for ascorbic acid degradation, add multivitamin product to TPN solution immediately prior to infusion or administer multivitamin and Copper (Feroglobin Capsules) in separate containers. Consider therapy modification

Dosage of Folic Acid (Feroglobin Capsules) in details

Folic Acid (Feroglobin Capsules) Dosage

Applies to the following strength(s): 1 mg; 0.4 mg; 5 mg/mL; 0.8 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Megaloblastic Anemia

1 mg orally, intramuscularly, subcutaneously or IV once a day. May continue until clinical symptoms of folate deficiency and the hematological profile have normalized.

Usual Adult Dose for Folic Acid (Feroglobin Capsules) Deficiency

400 to 800 mcg orally, intramuscularly, subcutaneously or IV once a day.

Women of childbearing age, pregnant, and lactating women: 800 mcg orally, intramuscularly, subcutaneously or IV once a day.

Usual Pediatric Dose for Folic Acid (Feroglobin Capsules) Deficiency

Infant:

0.1 mg orally, intramuscularly, subcutaneously or IV once a day.

Child:

Less than 4 years: up to 0.3 mg orally, intramuscularly, subcutaneously or IV once a day.

4 years or older: 0.4 mg orally, intramuscularly, subcutaneously or IV once a day.

Usual Pediatric Dose for Vitamin/Mineral Supplementation

Recommended daily allowance (RDA):

Premature neonates: 50 mcg/day (15 mcg/kg/day).

Full-term neonates and infants 1 to 6 months: 25 to 35 mcg/day.

Children:

1 to 3 years: 150 mcg/day.

4 to 8 years: 200 mcg/day.

9 to 13 years: 300 mcg/day.

14 years and older: 400 mcg/day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Rarely, a dosage of 2 mg/day may be required, particularly in patients with malabsorption, alcoholism, chronic hemolysis, chronic exfoliative skin disease or who are on concomitant anticonvulsant therapy.

Dialysis

Folic Acid (Feroglobin Capsules) is removed by both hemodialysis and peritoneal dialysis. The amount removed varies with type equipment used.

Because folate may accumulate in patients with end-stage renal disease, side effects may be more likely in this patient who is undergoing dialysis. Once this patient's body stores of folate are replete, three times a week dosing may be just as beneficial as once daily dosing but should portend a lower risk of side effects.

Other Comments

The recommended daily allowance of Folic Acid (Feroglobin Capsules) for adult males and females ranges from 150 to 200 and 150 to 180 mcg/day, respectively.

There is a potential danger in administering Folic Acid (Feroglobin Capsules) to patients with undiagnosed anemia, since Folic Acid (Feroglobin Capsules) may obscure the diagnosis of pernicious anemia by alleviating the hematologic manifestations of the disease while allowing the neurologic complications to progress.

Severe megaloblastic anemia may require therapy for 4 to 5 weeks. Once stabilized, if dietary intake is inadequate, maintenance therapy can be started.

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What other drugs will affect Folic Acid (Feroglobin Capsules)?

The dosages of other medications you take may need to be changed while you are taking Folic Acid (Feroglobin Capsules).

Tell your doctor about all other medications you use, especially:

This list is not complete and there may be other drugs that can interact with Folic Acid (Feroglobin Capsules). Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Folic Acid (Feroglobin Capsules) interactions

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Medications that interfere with your bodys ability to use folate may also increase the need for this vitamin. Medications can interfere with folate utilization, including: anticonvulsant medications (such as phenytoin, and primidone) metformin (sometimes prescribed to control blood sugar in type 2 diabetes) sulfasalazine (used to control inflammation associated with Crohns disease and ulcerative colitis) triamterene (a diuretic) Methotrexate There has been concern about the interaction between vitamin B12 and Folic Acid (Feroglobin Capsules). Folic Acid (Feroglobin Capsules) supplements can correct the anemia associated with vitamin B12 deficiency. Unfortunately, Folic Acid (Feroglobin Capsules) will not correct changes in the nervous system that result from vitamin B12 deficiency. Permanent nerve damage could theoretically occur if vitamin B12 deficiency is not treated. Therefore, intake of supplemental Folic Acid (Feroglobin Capsules) should not exceed 1000 micrograms (g, sometimes mcg) per day to prevent Folic Acid (Feroglobin Capsules) from masking symptoms of vitamin B12 deficiency. It is important for older adults to be aware of the relationship between Folic Acid (Feroglobin Capsules) and vitamin B12 because they are at greater risk of having a vitamin B12 deficiency. If you are 50 years of age or older, ask your physician to check your B12 status before you take a supplement that contains Folic Acid (Feroglobin Capsules).

Dosage of Iron (Feroglobin Capsules) in details

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Film-Coated Tablet: Treatment of Iron Deficiency with Reduced Number of Red Blood Cells in Adults and Children over 12 Years: 1 to 3 tablets once daily or divided into separate doses for about 3 to 5 months.

After normalisation of the red blood pigment (haemoglobin) value, continue with 1 tablet once daily for several weeks. This will replenish the iron stores.

Treatment of Iron Deficiency with Reduced Number of Red Blood Cells in Pregnancy: 2 to 3 tablets once daily or divided into separate doses.

After normalisation of the red blood pigment value, continue with 1 tablet once daily until, at least, the end of pregnancy. This will replenish the iron stores and provide the increased amount of iron required during pregnancy.

Treatment of Iron Deficiency with Normal Number of Red Blood Cells in Adults, Pregnancy, and Children over 12 years, and Prevention of Iron Deficiency in Pregnancy: 1 tablet once daily for 1 to 2 months.

Syrup: Adults: 5 mL 2 to 3 times daily before meals.

Children: 5 mL 1 to 2 times daily before meals.

Infants: Begin with 2.5 mL daily and gradually increase to 5 mL daily.

Drops: Adults: 20 drops 2 to 3 times daily during or after a meal.

Children: 20 drops 1 to 2 times daily during or after a meal.

Infants: Begin with 6 drops daily and gradually increase to 20 drops daily.

Iron (Feroglobin Capsules) may be mixed with fruit, vegetable juices or other liquids if desired.

Best results are obtained by adequate dosage and regular administration. It is recommended that the therapy in conformity to the degree of iron deficiency should be continued for at least 1 to 2 months.

Administration: Take Iron (Feroglobin Capsules) during or immediately after meal.

Duration of use depends upon the degree of iron deficiency.

Do not discontinue sooner than recommended as this may reduce the success of therapy.

What other drugs will affect Iron (Feroglobin Capsules)?

Ask a doctor or pharmacist if it is safe for you to use carbonyl iron if you are also using any of the following drugs:

This list is not complete. Other drugs may interact with carbonyl iron, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Iron (Feroglobin Capsules) interactions

Drug interactions were not noted and were not studied in clinical studies.

Feridex I.V. (ferumoxides injectable solution) administration provides elemental iron. In patients who are receiving supplemental iron orally or parenterally, the dose of supplemental iron may need to be decreased.

The effect of concomitant parenteral iron on Feridex I.V. dosing is not known.

Laboratory Test Findings

Serum iron levels may be above the normal range following Feridex I.V. (ferumoxides injectable solution) administration. Transient increases in serum iron of 15–100% of baseline were observed 18 to 24 hours after Feridex I.V. (ferumoxides injectable solution) administration, and returned to normal in most patients by 7 days after administration. Increases in serum ferritin levels were seen 1 to 7 days after administration.

In a Phase 1 study in normal subjects, PTT was statistically significantly increased; however, all values were within the normal range and no subjects had a more than 40% increase from baseline. In clinical trials of patients who had baseline hematologic abnormalities associated with underlying liver disease, an effect of Feridex I.V. (ferumoxides injectable solution) on platelet or PTT was not demonstrated. In patients with low hematocrit and hemoglobin, over a period of 48 hours to 7 days after Feridex I.V. (ferumoxides injectable solution), the serum iron, the hematocrit and hemoglobin levels increase slightly.

Dosage of Vitamin B (Feroglobin Capsules) in details

Initially 3ml i.m daily. Subsequently 2-3 times/week.

Vitamin B (Feroglobin Capsules) interactions

If you are taking this product under your doctor's direction, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not stop, start, or change the dosage of any medicine before checking with them first.

Before using this product, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: altretamine, cisplatin, certain antibiotics (e.g., chloramphenicol), certain anti-seizure drugs (e.g., phenytoin), levodopa, other vitamin/nutritional supplements.

This product may interfere with certain laboratory tests (e.g., urobilinogen, intrinsic factor antibodies), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this product.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Dosage of Zinc (Feroglobin Capsules) in details

Zinc (Feroglobin Capsules) 1 mg/mL (Zinc (Feroglobin Capsules) Chloride Injection, USP) contains 1 mg Zinc (Feroglobin Capsules)/mL and is administered intravenously only after dilution. The additive should be diluted prior to administration in a volume of fluid not less than 100 mL. For the metabolically stable adult receiving TPN, the suggested intravenous dosage is 2.5 to 4 mg Zinc (Feroglobin Capsules)/day (2.5 to 4 mL/day). An additional 2 mg Zinc (Feroglobin Capsules)/day (2 mL/day) is suggested for acute catabolic states. For the stable adult with fluid loss from the small bowel, an additional 12.2 mg Zinc (Feroglobin Capsules)/liter of small bowel fluid lost (12.2 mL/liter of small bowel fluid lost), or an additional 17.1 mg Zinc (Feroglobin Capsules)/kg of stool or ileostomy output (17.1 mL/kg of stool or ileostomy output) is recommended. Frequent monitoring of Zinc (Feroglobin Capsules) blood levels is suggested for patients receiving more than the usual maintenance dosage level of Zinc (Feroglobin Capsules).

For full term infants and children up to 5 years of age, 100 mcg Zinc (Feroglobin Capsules)/kg/day

(0.1 mL/kg/day) is recommended. For premature infants (birth weight less than 1500 g) up to 3 kg in body weight, 300 mcg Zinc (Feroglobin Capsules)/kg/day (0.3 mL/kg/day) is suggested.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.

How supplied

Zinc (Feroglobin Capsules) 1 mg/mL (Zinc (Feroglobin Capsules) Chloride Injection, USP) is supplied in 10 mL Plastic Vials (List No. 4090).

Store at 20 to 25°C (68 to 77°F).

HOSPIRA, INC., LAKE FOREST, IL 60045 USA. Revised: October, 2004

What other drugs will affect Zinc (Feroglobin Capsules)?

Other drugs may interact with Zinc (Feroglobin Capsules) sulfate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Zinc (Feroglobin Capsules) interactions

Pyridoxine reduces the effects of levodopa (but this does not occur if a dopa decarboxylase is also given); decreases serum concentrations of phenobarbitone. Concurrent administration of drugs eg, isoniazid, penicillamine and oral contraceptives increase the requirement for pyridoxine.

Absorption of cyanocobalamin from the GIT may be reduced by neomycin, aminosalicylic acid, histamine H2-receptor antagonists and colchicine. Serum concentrations may be decreased by concurrent administration of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should be taken into account when performing assays for blood concentrations.

Parenteral chloramphenicol may attenuate the effect of vitamin B12 in anaemia.

Folate deficiency states may be produced by a number of drugs including antiepileptics, oral contraceptives, antituberculous drugs, alcohol and Zinc (Feroglobin Capsules) antagonists eg, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides; Zinc (Feroglobin Capsules) may decrease serum-phenytoin concentrations.

There may be an increased risk of myopathy or rhabdomyolysis when nicotinic acid is used concurrently with statins. Nicotinamide may increase the requirements for insulin or oral hypoglycaemics.

Ascorbic acid may increase the absorption of iron-deficiency states.

Ascorbic acid is often given in addition to desferrioxamine to patients with iron overload (thalassemia) to achieve better iron excretion. However, early on in treatment when there is excess tissue iron, there is some evidence that ascorbic acid may worsen the iron toxicity, particularly to the heart. Thus, ascorbic acid should not be given for the first month after starting desferrioxamine treatment.

The absorption of Zinc (Feroglobin Capsules) may be reduced by iron supplements, penicillamine, phosphorus-containing preparations and tetracyclines. Zinc (Feroglobin Capsules) supplements reduce the absorption of Zinc (Feroglobin Capsules), ciprofloxacin, iron, norfloxacin, penicillamine and tetracyclines.



References

  1. DailyMed. "ASCORBIC ACID; BIOTIN; CYANOCOBALAMIN; DEXPANTHENOL; ERGOCALCIFEROL; FOLIC ACID; NIACINAMIDE; PHYTONADIONE; PYRIDOXINE HYDROCHLORIDE; RIBOFLAVIN 5'-PHOSPHATE SODIUM; THIAMINE HYDROCHLORIDE; VITAMIN A; VITAMIN E: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "COPPER: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. FDA/SPL Indexing Data. "J41CSQ7QDS: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Feroglobin Capsules are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Feroglobin Capsules. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

26 consumers reported frequency of use

How frequently do I need to take Feroglobin Capsules?
It was reported by ndrugs.com website users that Feroglobin Capsules should ideally be taken Twice in a day as the most common frequency of the Feroglobin Capsules. You should you adhere strictly to the instructions and guidelines provided by your doctor on how frequently this Feroglobin Capsules should be taken. Get another patient's view on how frequent the capsule should be used by clicking here.
Users%
Twice in a day17
65.4%
Once in a day8
30.8%
4 times in a day1
3.8%


7 consumers reported doses

What doses of Feroglobin Capsules drug you have used?
The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Feroglobin Capsules drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
Users%
1-5mg4
57.1%
101-200mg1
14.3%
201-500mg1
14.3%
11-50mg1
14.3%


Consumer reviews

Ibrahim05 Jun 2018 05:40
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Information checked by Dr. Sachin Kumar, MD Pharmacology

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