What is Flex-All 454?
Flex-All 454 (for the skin) is used for temporary relief of muscle or joint pain caused by strains, sprains, arthritis, bruising, or backaches.
Flex-All 454 may also be used for purposes not listed in this medication guide.
Flex-All 454 indications
Flex-All 454 Arthritis Pain Relief Ointment For the temporary relief of minor aches and pains of muscle and joints associated with arthritis.
How should I use Flex-All 454?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Make sure your skin is clean and dry before you apply Flex-All 454.
Do not apply methyl salicylate to open wounds, or to skin that is sunburned, windburned, dry, chapped, or otherwise irritated.
When using Flex-All 454 cream, gel, lotion, oil, ointment, or spray: apply a thin layer to the affected area and rub in gently until completely absorbed.
To use the liquid or stick, uncap the applicator and press it firmly on your skin to apply the medication. Massage gently onto the affected are until completely absorbed.
To apply a Flex-All 454 skin patch, remove the liner and apply the patch to your skin over the area of pain. Press the edges firmly into place. Remove the patch and apply a new patch 1 or 2 times daily if needed.
Flex-All 454 may be used up to 4 times daily or as directed on the medicine label.
Wash your hands with soap and water immediately after applying Flex-All 454 or handling the skin patch. If you have applied the medicine to your hands or fingers to treat pain in those areas, wait at least 30 minutes before washing your hands.
To keep the medication from getting on your fingers when you apply it, you may use a rubber glove, finger cot, cotton ball, or clean tissue to apply the medicine.
Methyl salicylate can cause a cold or burning sensation wherever it is applied. This sensation is usually mild and should gradually lessen over time.
If the burning sensation is painful or causes significant discomfort, wash the treated skin area with soap and cool water. Get medical attention right away if you have severe burning, pain, swelling, or blistering.
Do not cover treated skin with a bandage or heating pad, which can increase the burning sensation. You may cover the skin with clothing.
Avoid getting this medication in your eyes. If this does happen, rinse with water.
Also avoid getting this medication on contact lenses, dentures, and other items that come into contact with sensitive areas of your body.
Avoid applying methyl salicylate right after bathing or shaving. Using this medication on freshly shaved skin areas can cause severe skin irritation.
Call your doctor if your pain does not improve after using this medication for 7 days, or if your symptoms get worse or get better and then come back in a few days.
Store this medication at room temperature away from moisture and heat, in a place where children and pets cannot get to it.
Uses of Flex-All 454 in details
This product is used to treat minor aches and pains of the muscles/joints (e.g., arthritis, backache, sprains). Menthol and methyl salicylate are known as counterirritants. They work by causing the skin to feel cool and then warm. These feelings on the skin distract you from feeling the aches/pains deeper in your muscles, joints, and tendons.
Some products should not be used on children younger than 12 years without a doctor's advice. Check the label carefully before using on children between 2 and 12 years old. Do not use on children younger than 2 years.
How to use Flex-All 454 topical
Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.
This medication is for use on the skin only. Do not apply near the eyes, mouth, nose, or genitals, and be careful not to touch those areas while the medication is on your hands. If you do get the medication in those areas, flush with plenty of water. Wash your hands well before inserting contact lenses.
If you are using the lotion, spray, or foam, shake the bottle well before using.
Apply a thin layer of medication to the affected area no more than 3 to 4 times a day. Rub in gently and thoroughly. After applying the medication, wash your hands unless you are using this medication to treat the hands. If treating the hands, wait at least 30 minutes after applying the medication to wash your hands.
Do not apply this medication to skin that is injured or irritated (e.g., cut, scraped, sunburned). Do not bandage or tightly wrap the affected area. Doing so may increase the risk of side effects. You may cover the area loosely to protect clothing. Ask your pharmacist for more details.
Heat can increase the risk of side effects. Do not apply this medication immediately before, during, or after activities that increase skin temperature (e.g., bathing in hot water, swimming, sun bathing, heavy exercise) or in hot/humid weather. Wait until your skin has cooled before applying the medication. Do not use a sunlamp/tanning bed, hot water bottle, or heating pad on the treated area.
This product is available in different strengths and with different ingredients but with product names that sound similar. Read the label carefully to make sure you have the right product for you. Ask your pharmacist if you have any questions.
Tell your doctor if your condition persists for more than 7 days, if it worsens, or if it keeps returning. If you think you may have a serious medical problem, seek immediate medical attention.
Flex-All 454 description
Each 100 g of cream contains methyl salicylate 11 g, eugenol 1.4 g, menthol 5.6 g, cajuput oil 0.8 g and washable base.
Flex-All 454 dosage
Apply to the affected area not more than qid.
Flex-All 454 interactions
See also:
What other drugs will affect Flex-All 454?
If you are using this product under your doctor's direction, your doctor or pharmacist may already be aware of possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
Before using this product, tell your doctor or pharmacist if you use any of the following products: "blood thinners" (e.g., warfarin).
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Flex-All 454 side effects
See also:
What are the possible side effects of Flex-All 454?
Redness, warmth, stinging, or burning on the application site may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Stop using this medication and tell your doctor right away if any of these unlikely but serious side effects occur: blistering/swelling/severe redness at the application site, increased/unusual pain at the application site, nausea/vomiting, ringing in the ears.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Flex-All 454 contraindications
See also:
What is the most important information I should know about Flex-All 454?
Active peptic ulcer; pregnancy (3rd trimester), hypersensitivity to aspirin and other NSAIDs; treatment of perioperative pain in CABG surgery; severe renal impairment; rectal admin in patients with proctitis and haemorrhoids; neonates with necrotizing enterocolitis, active bleeding, thrombocytopenia, coagulation defects and untreated infections.
Active ingredient matches for Flex-All 454:
Menthol/methyl salicylate in United States.
| Unit description / dosage (Manufacturer) | Price, USD |
| Gel; Topical; Menthol 7% | |
| Gel; Topical; Menthol 16% | |
| Jelly; Topical; Menthol 10% | |
List of Flex-All 454 substitutes (brand and generic names): | |
| Flex-All Stick | |
| Strips; Topical; Menthol; Methyl Salicylate | |
| Formula P1 | |
| Ointment; Topical; Menthol 2%; Methyl Salicylate 0.5% | |
| Gordogesic | |
| Heet Analgesic Liniment | |
| Liquid; Topical; Camphor 3.5%; Capsaicin 0.025%; Methyl Salicylate 18% | |
| Heet Triple Action | |
| Hot Ize (Thailand) | |
| Hot Ize 10 g x 1's (Anb) | |
| Hot Ize 30 g x 1's (Anb) | |
| Improved Analgesic (United States) | |
| Instant Rub (Canada) | |
| Instant Rub Ointment | |
| Ointment; Topical; Menthol 40 mg; Methyl Salicylate 100 mg / g | |
| Kobi | |
| Cream; Topical; Menthol 2%; Methyl Salicylate 10% | |
| Konibalm (Indonesia) | |
| Listermint arctic fresh (Indonesia) | |
| Marathon Deep Heat Rub | |
| Lotion; Topical; Menthol 10%; Methyl Salicylate 15% | |
| Menthol C | |
| Menthol/methyl salicylate (Indonesia) | |
| Mentholatum Deep Heating | |
| Mentholatum Deep Heating Lotion | |
| Lotion; Topical; Menthol 60 mg; Methyl Salicylate 200 mg / g | |
| Mentholatum Deep Heating Rub | |
| Liquid; Topical; Menthol 58.8 mg; Methyl Salicylate 127.3 mg / g | |
| Mentholatum Ointment | |
| Ointment; Topical; Camphor 90 mg; Menthol 13.5 mg / g (Hofmann) | |
| Mentholatum Pain Gel | |
| Mentholatum Pain Patch | |
| Menzza/Menzza Ice/Menzza NP/Menzza OA (Malaysia) | |
| Menzza cream 15 g x 1's (Hoe Pharma) | |
| Menzza cream 25 g x 1's (Hoe Pharma) | |
| Menzza cream 50 g x 1's (Hoe Pharma) | |
| Menzza NP cream 0.075 % w/w 25 g x 1's (Hoe Pharma) | |
| Menzza OA cream 0.025 % w/w 25 g x 1's (Hoe Pharma) | |
| Menzza Ice topical gel 4 % 25 g x 1's (Hoe Pharma) | |
| Menzza Ice topical gel 4 % 50 g x 1's (Hoe Pharma) | |
| methyl salicylate topical | |
| Methyl salicylate/ menthol cream | |
| Methyl salicylate/ menthol lotion | |
| Methyl Salicylate/Menthol (Vietnam) | |
| Methyl Salicylate/Menthol Cream | |
| Methyl Salicylate/Menthol Lotion | |
| Minard's Joint Relief | |
| Cream; Topical; Menthol 8%; Methyl Salicylate 30% | |
| Minard`s joint relief (Canada) | |
| Minit Rub | |
| Mueller Gesic | |
| Ointment; Topical; Menthol 6.3%; Methyl Salicylate 15.04% | |
| Musaid A (Taiwan) | |
| Musaid A 20 g | |
| MUSLAX CRM (India) | |
| 15g (Bio E) | $ 0.23 |
| MUSLAX CRM cream 15g (Bio E) | $ 0.23 |
See 151 substitutes for Flex-All 454 | |
References
- DailyMed. "MENTHOL; METHYL SALICYLATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "methyl salicylate". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Methyl salicylate". http://www.drugbank.ca/drugs/DB09543 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Flex-All 454 are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Flex-All 454. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
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Information checked by Dr. Sachin Kumar, MD Pharmacology
