Dosage of Insulin Glargine Cartridge Systems in details
Insulin Glargine Cartridge Systems Dosage
Generic name: Insulin Glargine Cartridge Systems 100[iU] in 1mL
Dosage form: injection, solution
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Important Administration Instructions
- Always check insulin labels before administration.
- Train patients on proper use and injection technique before initiating Insulin Glargine Cartridge Systems.
- Visually inspect Insulin Glargine Cartridge Systems KwikPen for particulate matter and discoloration prior to administration. Only use if the solution is clear and colorless with no visible particles.
- ​Inject between 1 and 80 units per injection.
- Administer Insulin Glargine Cartridge Systems subcutaneously into the abdominal area, thigh, or deltoid, and rotate injection sites within the same region from one injection to the next to reduce the risk of lipodystrophy.
- Do not dilute or mix Insulin Glargine Cartridge Systems with any other insulin or solution as the onset of action or time to peak effect of Insulin Glargine Cartridge Systems and the mixed insulin may be altered in an unpredictable manner.
- Do not administer intravenously or via an insulin pump because this could result in severe hypoglycemia.
General Dosing Instructions
- In patients with type 1 diabetes, Insulin Glargine Cartridge Systems must be used concomitantly with short-acting insulin.
- Inject Insulin Glargine Cartridge Systems subcutaneously once daily at any time of day but at the same time every day.
- Individualize and titrate the dosage of Insulin Glargine Cartridge Systems based on the individual's metabolic needs, blood glucose monitoring results and glycemic control goal.
- Dosage adjustments may be needed with changes in physical activity, changes in meal patterns (i.e., macronutrient content or timing of food intake), during acute illness, or changes in renal or hepatic function and should be made under medical supervision with appropriate glucose monitoring.
Initiation of Insulin Glargine Cartridge Systems Therapy
- The recommended starting dose of Insulin Glargine Cartridge Systems in patients with type 1 diabetes should be approximately one-third of the total daily insulin requirements. Short- or rapid-acting, pre-meal insulin should be used to satisfy the remainder of the daily insulin requirements.
- The recommended starting dose of Insulin Glargine Cartridge Systems in patients with type 2 diabetes is 0.2 units/kg or up to 10 units once daily. One may need to adjust the amount and timing of short- or rapid-acting insulins and dosages of any anti-diabetic drugs.
Changing to Insulin Glargine Cartridge Systems from Other Insulin Therapies
- If changing patients from another Insulin Glargine Cartridge Systems product, 100 units/mL, to Insulin Glargine Cartridge Systems, the dose of Insulin Glargine Cartridge Systems should be the same as the other Insulin Glargine Cartridge Systems product, 100 units/mL, and the time of day for administration should be determined by the physician.
- If changing patients from a once-daily Insulin Glargine Cartridge Systems product, 300 units/mL, to once-daily Insulin Glargine Cartridge Systems, the recommended initial Insulin Glargine Cartridge Systems dosage is 80% of the Insulin Glargine Cartridge Systems product, 300 units/mL, dose that is being discontinued. This dosage reduction will lower the likelihood of hypoglycemia.
- If changing from a treatment regimen with an intermediate- or long-acting insulin (other than an Insulin Glargine Cartridge Systems product, 100 units/mL) to a regimen with Insulin Glargine Cartridge Systems, a change in the dose of the basal insulin may be required and the amount and timing of shorter-acting insulins and doses of any anti-diabetic drugs may need to be adjusted.
- If changing patients from twice-daily NPH insulin to once-daily Insulin Glargine Cartridge Systems, the recommended initial Insulin Glargine Cartridge Systems dosage is 80% of the total NPH dosage that is being discontinued. This dosage reduction will lower the likelihood of hypoglycemia.
More about Insulin Glargine Cartridge Systems (Insulin Glargine Cartridge Systems)
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- During Pregnancy
- Dosage Information
- Drug Interactions
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Consumer resources
- Insulin Glargine Cartridge Systems
- Insulin Glargine Cartridge Systems KwikPen
- Insulin Glargine Cartridge Systems (Advanced Reading)
- Other brands: Lantus, Toujeo, Toujeo Solostar, Lantus Solostar
Professional resources
- Insulin Glargine Cartridge Systems (FDA)
- Insulin Glargine Cartridge Systems (AHFS Monograph)
Related treatment guides
- Diabetes, Type 1
- Diabetes, Type 2
What other drugs will affect Insulin Glargine Cartridge Systems?
Many drugs can affect your blood sugar and may also affect Insulin Glargine Cartridge Systems. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use. Not all possible interactions are listed here.
Insulin Glargine Cartridge Systems drug interactions (more detail)
Insulin Glargine Cartridge Systems interactions
Table 6 includes clinically significant drug interactions with Insulin Glargine Cartridge Systems
Table 6: Clinically Significant Drug Interactions with Insulin Glargine Cartridge Systems
Drugs That May Increase the Risk of Hypoglycemia | |
Drugs: | Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics. |
Intervention: | Dose reductions and increased frequency of glucose monitoring may be required when Insulin Glargine Cartridge Systems is co-administered with these drugs. |
Drugs That May Decrease the Blood Glucose Lowering Effect of Insulin Glargine Cartridge Systems | |
Drugs: | Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones |
Intervention: | Dose increases and increased frequency of glucose monitoring may be required when Insulin Glargine Cartridge Systems is co-administered with these drugs. |
Drugs That May Increase or Decrease the Blood Glucose Lowering Effect of Insulin Glargine Cartridge Systems | |
Drugs: | Alcohol, beta-blockers, clonidine, and lithium salts. Pentamidine may cause hypoglycemia, which may sometimes be followed by hyperglycemia. |
Intervention: | Dose adjustment and increased frequency of glucose monitoring may be required when Insulin Glargine Cartridge Systems is co-administered with these drugs. |
Drugs That May Blunt Signs and Symptoms of Hypoglycemia | |
Drugs: | beta-blockers, clonidine, guanethidine, and reserpine |
Intervention: | Increased frequency of glucose monitoring may be required when Insulin Glargine Cartridge Systems is coadministered with these drugs. |
Reviews
The results of a survey conducted on ndrugs.com for Insulin Glargine Cartridge Systems are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Insulin Glargine Cartridge Systems. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported frequency of use
No survey data has been collected yet1 consumer reported doses
What doses of Insulin Glargine Cartridge Systems drug you have used?The drug can be in various doses. Most anti-diabetic, anti-hypertensive drugs, pain killers, or antibiotics are in different low and high doses and prescribed by the doctors depending on the severity and demand of the condition suffered by the patient. In our reports, ndrugs.com website users used these doses of Insulin Glargine Cartridge Systems drug in following percentages. Very few drugs come in a fixed dose or a single dose. Common conditions, like fever, have almost the same doses, e.g., [acetaminophen, 500mg] of drug used by the patient, even though it is available in various doses.
Users | % | ||
---|---|---|---|
501mg-1g | 1 | 100.0% |
Consumer reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology