Actions of Lagesil in details
Lagesil acts rapidly in raising the pH of the gastric contents by reducing the concentration of acid in the gastric juice. The balance formula of Lagesil results in a product virtually free of constipative or laxative effects. Magnesium trisilicate reacts with the acid gastric content to neutralize the acid and forms hydrated silica gel which protects ulcerated mucosal surfaces and favors healing. Aluminium hydroxide raises gastric pH more slowly than calcium or magnesium antacids. Dimethylpolysiloxane is a physiologically inert, nonsystemic defoaming agent that works by altering the elasticity of interfaces of mucus-embedded bubbles in the gastrointestinal tract. The change in the surface tension of the small bubbles enables them to be broken up and then coalesce. This gaseous form is more easily eliminated from the gastrointestinal tract.
Pharmacokinetics: Aluminium hydroxide slowly reacts with hydrochloric acid in the stomach to form soluble aluminium chloride, some of which is absorbed. Absorbed aluminium is eliminated in the urine. Magnesium trisilicate reacts slowly with hydrochloric acid in the gastric secretion to form magnesium chloride and silicon dioxide and is primarily excreted in the faeces as insoluble and soluble magnesium salts. Small amounts of the derivatives may be absorbed and eliminated in the urine.
References
- DailyMed. "MAGNESIUM HYDROXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- NCIt. "Magnesium Hydroxide: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
- EPA Safer Choice. "EPA Safer Chemical Ingredients Classification: Safer Choice of the U.S. Environmental Protection Agency (EPA) helps consumers, businesses, and purchasers find products that perform and are safer for human health and the environment. This classification is created based on the use classes of each chemical ingredient from the EPA Safer Choice.". https://www.epa.gov/saferchoice (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Lagesil are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Lagesil. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported administration
When best can I take Lagesil, on an empty stomach, before or after food?ndrugs.com website users have also released a report stating that Lagesil should be taken After food. In any case, this may not be the right description on how you ought to take this Lagesil. Kindly visit your doctor for more medical advice in this regard. Click here to see other users view on when best the Lagesil can be taken.
| Users | % | ||
|---|---|---|---|
| After food | 1 | 100.0% | |
Consumer reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology
