• Dosage of Lantus OptiClik Cartridge in details
• Lantus OptiClik Cartridge interactions
• Lantus OptiClik Cartridge reviews

Dosage of Lantus OptiClik Cartridge in details

Lantus OptiClik Cartridge Dosage

Generic name: Lantus OptiClik Cartridge 100[iU] in 1mL

Dosage form: injection, solution

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Important Administration Instructions

• Always check insulin labels before administration.
• Train patients on proper use and injection technique before initiating Lantus OptiClik Cartridge.
• Visually inspect Lantus OptiClik Cartridge KwikPen for particulate matter and discoloration prior to administration. Only use if the solution is clear and colorless with no visible particles.
• ​Inject between 1 and 80 units per injection.
• Administer Lantus OptiClik Cartridge subcutaneously into the abdominal area, thigh, or deltoid, and rotate injection sites within the same region from one injection to the next to reduce the risk of lipodystrophy.
• Do not dilute or mix Lantus OptiClik Cartridge with any other insulin or solution as the onset of action or time to peak effect of Lantus OptiClik Cartridge and the mixed insulin may be altered in an unpredictable manner.
• Do not administer intravenously or via an insulin pump because this could result in severe hypoglycemia.

General Dosing Instructions

• In patients with type 1 diabetes, Lantus OptiClik Cartridge must be used concomitantly with short-acting insulin.
• Inject Lantus OptiClik Cartridge subcutaneously once daily at any time of day but at the same time every day.
• Individualize and titrate the dosage of Lantus OptiClik Cartridge based on the individual's metabolic needs, blood glucose monitoring results and glycemic control goal.
• Dosage adjustments may be needed with changes in physical activity, changes in meal patterns (i.e., macronutrient content or timing of food intake), during acute illness, or changes in renal or hepatic function and should be made under medical supervision with appropriate glucose monitoring.

Initiation of Lantus OptiClik Cartridge Therapy

• The recommended starting dose of Lantus OptiClik Cartridge in patients with type 1 diabetes should be approximately one-third of the total daily insulin requirements. Short- or rapid-acting, pre-meal insulin should be used to satisfy the remainder of the daily insulin requirements.
• The recommended starting dose of Lantus OptiClik Cartridge in patients with type 2 diabetes is 0.2 units/kg or up to 10 units once daily. One may need to adjust the amount and timing of short- or rapid-acting insulins and dosages of any anti-diabetic drugs.

Changing to Lantus OptiClik Cartridge from Other Insulin Therapies

• If changing patients from another Lantus OptiClik Cartridge product, 100 units/mL, to Lantus OptiClik Cartridge, the dose of Lantus OptiClik Cartridge should be the same as the other Lantus OptiClik Cartridge product, 100 units/mL, and the time of day for administration should be determined by the physician.
• If changing patients from a once-daily Lantus OptiClik Cartridge product, 300 units/mL, to once-daily Lantus OptiClik Cartridge, the recommended initial Lantus OptiClik Cartridge dosage is 80% of the Lantus OptiClik Cartridge product, 300 units/mL, dose that is being discontinued. This dosage reduction will lower the likelihood of hypoglycemia.
• If changing from a treatment regimen with an intermediate- or long-acting insulin (other than an Lantus OptiClik Cartridge product, 100 units/mL) to a regimen with Lantus OptiClik Cartridge, a change in the dose of the basal insulin may be required and the amount and timing of shorter-acting insulins and doses of any anti-diabetic drugs may need to be adjusted.
• If changing patients from twice-daily NPH insulin to once-daily Lantus OptiClik Cartridge, the recommended initial Lantus OptiClik Cartridge dosage is 80% of the total NPH dosage that is being discontinued. This dosage reduction will lower the likelihood of hypoglycemia.

More about Lantus OptiClik Cartridge (Lantus OptiClik Cartridge)

• Side Effects
• During Pregnancy
• Dosage Information
• Drug Interactions
• Support Group
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Consumer resources

• Lantus OptiClik Cartridge
• Lantus OptiClik Cartridge KwikPen
• Lantus OptiClik Cartridge (Advanced Reading)

• Other brands: Lantus, Toujeo, Toujeo Solostar, Lantus Solostar

Professional resources

• Lantus OptiClik Cartridge (FDA)
• Lantus OptiClik Cartridge (AHFS Monograph)

Related treatment guides

• Diabetes, Type 1
• Diabetes, Type 2

What other drugs will affect Lantus OptiClik Cartridge?

Many drugs can affect your blood sugar and may also affect Lantus OptiClik Cartridge. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use. Not all possible interactions are listed here.

Lantus OptiClik Cartridge drug interactions (more detail)

Lantus OptiClik Cartridge interactions

Table 6 includes clinically significant drug interactions with Lantus OptiClik Cartridge

Table 6: Clinically Significant Drug Interactions with Lantus OptiClik Cartridge

Drugs That May Increase the Risk of Hypoglycemia
Drugs:	Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics.
Intervention:	Dose reductions and increased frequency of glucose monitoring may be required when Lantus OptiClik Cartridge is co-administered with these drugs.
Drugs That May Decrease the Blood Glucose Lowering Effect of Lantus OptiClik Cartridge
Drugs:	Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones
Intervention:	Dose increases and increased frequency of glucose monitoring may be required when Lantus OptiClik Cartridge is co-administered with these drugs.
Drugs That May Increase or Decrease the Blood Glucose Lowering Effect of Lantus OptiClik Cartridge
Drugs:	Alcohol, beta-blockers, clonidine, and lithium salts. Pentamidine may cause hypoglycemia, which may sometimes be followed by hyperglycemia.
Intervention:	Dose adjustment and increased frequency of glucose monitoring may be required when Lantus OptiClik Cartridge is co-administered with these drugs.
Drugs That May Blunt Signs and Symptoms of Hypoglycemia
Drugs:	beta-blockers, clonidine, guanethidine, and reserpine
Intervention:	Increased frequency of glucose monitoring may be required when Lantus OptiClik Cartridge is coadministered with these drugs.

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Information checked by Dr. Sachin Kumar, MD Pharmacology