What are the possible side effects of Lincover?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
- Abdominal or stomach cramps and pain (severe)
- abdominal tenderness
- diarrhea (watery and severe), which may also be bloody
- fever
- Skin rash, redness, and itching
- sore throat and fever
- unusual bleeding and bruising
Note: Some of the above side effects may also occur up to several weeks after you stop taking Lincover.
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Diarrhea (mild)
- nausea and vomiting
- stomach pain
- Itching of rectal or genital (sex organ) areas
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Side effects of Lincover in details
The following reactions have been reported with the use of Lincover:
Gastrointestinal
Glossitis, stomatitis, nausea, vomiting, antibacterial -associated diarrhea and colitis, and pruritus ani. Onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment.
Hematopoietic
Neutropenia, leukopenia, agranulocytosis and thrombocytopenic purpura have been reported. There have been rare reports of aplastic anemia and pancytopenia in which Lincover could not be ruled out as the causative agent.
Hypersensitivity Reactions
Hypersensitivity reactions such as angioneurotic edema, serum sickness and anaphylaxis have been reported. Cases of erythema multiforme, some resembling Stevens-Johnson syndrome, have been associated with Lincover.
Skin and Mucous Membranes
Skin rashes, urticaria and vaginitis and rare instances of exfoliative and vesiculobullous dermatitis have been reported.
Liver
Although no direct relationship of Lincover to liver dysfunction has been established, jaundice and abnormal liver function tests (particularly elevations of serum transaminase) have been observed.
Renal
Although no direct relationship of Lincover to renal damage has been established, renal dysfunction as evidenced by azotemia, oliguria, and/or proteinuria has been observed in rare instances.
Cardiovascular
After too rapid intravenous administration, rare instances of cardiopulmonary arrest and hypotension have been reported.
Special Senses
Tinnitus and vertigo have been reported occasionally.
Local Reactions
Patients have demonstrated excellent local tolerance to intramuscularly administered Lincover. Reports of pain following injection have been infrequent.
Intravenous administration of Lincover in 250 to 500 mL of 5% dextrose injection or 0.9% sodium chloride injection produced no local irritation or phlebitis.
What is the most important information I should know about Lincover?
- Tell your doctor or dentist that you take Lincover before you receive any medical or dental care, emergency care, or surgery.
- Lincover only works against bacteria; it does not treat viral infections (eg, the common cold).
- Be sure to use Lincover for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Long-term or repeated use of Lincover may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
- A severe skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Lincover has benzyl alcohol in it. Do not use it in NEWBORNS or INFANTS. It may cause serious and sometimes fatal side effects. If you have questions, check with your doctor or pharmacist.
- Lab tests may be performed while you use Lincover. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Lincover with caution in the ELDERLY; they may be more sensitive to its effects, especially diarrhea. Monitor carefully for changes in bowel frequency.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lincover while you are pregnant. Lincover is found in breast milk. Do not breast-feed while taking Lincover.
Lincover contraindications
Before receiving Lincover, tell your doctor if you have asthma or allergies, a stomach or intestinal disorder such as colitis, liver or kidney disease, or epilepsy or other seizure disorder.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
Serious side effects of Lincover include fever, chills, body aches, flu symptoms, white patches or sores inside your mouth or on your lips, severe blistering or peeling skin rash, feeling like you might pass out, easy bruising or bleeding, unusual weakness, or urinating less than usual or not at all.
References
- European Chemicals Agency - ECHA. "lincomycin: The European Chemicals Agency (ECHA) is an agency of the European Union which is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.". https://echa.europa.eu/ (accessed September 17, 2018).
- HSDB. "LINCOMYCIN". https://toxnet.nlm.nih.gov/cgi-bin/s... (accessed September 17, 2018).
- NCIt. "Lincomycin: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Lincover are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Lincover. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported side effects
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Information checked by Dr. Sachin Kumar, MD Pharmacology
