M-CIT Pregnancy

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Pregnancy of M-CIT in details

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A control group found no significant differences in pregnancy outcome including rate of live births, spontaneous or therapeutic abortion or stillbirth. There was also no difference in the rates of major or minor anomalies including mean birth weight, mode of delivery, gestational age, or presence of neonatal distress.

M-CIT has been assigned to pregnancy category B by the FDA. High dose animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. M-CIT is only recommended for use during pregnancy when need benefit outweighs risk.

See references

M-CIT breastfeeding

M-CIT is excreted into human milk. The manufacturer does not recommend the use of M-CIT in nursing mothers.

See references

References for pregnancy information

  1. "Product Information. Zyrtec (M-CIT)." Pfizer US Pharmaceuticals, New York, NY.
  2. Einarson A, Bailey B, Jung G, Spizzirri D, Baillie M, Koren G "Prospective controlled study of hydroxyzine and M-CIT in pregnancy." Ann Allergy Asthma Immunol 78 (1997): 183-6

References for breastfeeding information

  1. "Product Information. Zyrtec (M-CIT)." Pfizer US Pharmaceuticals, New York, NY.


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References

  1. DailyMed. "CETIRIZINE HYDROCHLORIDE; PSEUDOEPHEDRINE HYDROCHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubMed Health. "Zerviate: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
  3. Human Metabolome Database (HMDB). "Cetirizine: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).

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