Actions of Magnesium carbonate in details
Description: Magnesium carbonate is an antacid. It works to neutralise stomach acidity by reacting with hydrochloric acid to form soluble Magnesium carbonate chloride and carbon dioxide.
How should I take Magnesium carbonate?
This section provides information on the proper use of a number of products that contain Magnesium carbonate supplement. It may not be specific to Magnesium carbonate. Please read with care.
Magnesium carbonate supplements should be taken with meals. Taking Magnesium carbonate supplements on an empty stomach may cause diarrhea.
For individuals taking the extended-release form of this dietary supplement:
- Swallow the tablets whole. Do not chew or suck on the tablet.
- Some tablets may be broken or crushed and sprinkled on applesauce or other soft food. However, check with your health care professional first, since this should not be done for most tablets.
For individuals taking the powder form of this dietary supplement:
- Pour powder into a glass.
- Add water and stir.
Dosing
The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (capsules, chewable tablets, crystals for oral solution, extended-release tablets, enteric-coated tablets, powder for oral solution, tablets, oral solution):
- To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes (Note that the normal daily recommended intakes are expressed as an actual amount of Magnesium carbonate. The salt form [e.g., Magnesium carbonate chloride, Magnesium carbonate gluconate, etc.] has a different strength.):
- For the U.S.
- Adult and teenage males—270 to 400 milligrams (mg) per day.
- Adult and teenage females—280 to 300 mg per day.
- Pregnant females—320 mg per day.
- Breast-feeding females—340 to 355 mg per day.
- Children 7 to 10 years of age—170 mg per day.
- Children 4 to 6 years of age—120 mg per day.
- Children birth to 3 years of age—40 to 80 mg per day.
- For Canada
- Adult and teenage males—130 to 250 mg per day.
- Adult and teenage females—135 to 210 mg per day.
- Pregnant females—195 to 245 mg per day.
- Breast-feeding females—245 to 265 mg per day.
- Children 7 to 10 years of age—100 to 135 mg per day.
- Children 4 to 6 years of age—65 mg per day.
- Children birth to 3 years of age—20 to 50 mg per day.
- To treat deficiency:
- Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency.
- To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes (Note that the normal daily recommended intakes are expressed as an actual amount of Magnesium carbonate. The salt form [e.g., Magnesium carbonate chloride, Magnesium carbonate gluconate, etc.] has a different strength.):
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
If you miss taking your Magnesium carbonate supplement for one or more days there is no cause for concern, since it takes some time for your body to become seriously low in Magnesium carbonate. However, if your health care professional has recommended that you take Magnesium carbonate, try to remember to take it as directed every day.
Storage
Keep out of the reach of children.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Do not keep outdated medicine or medicine no longer needed.
Magnesium carbonate administration
Administer orally.
Magnesium carbonate pharmacology
Magnesium carbonate is important as a cofactor in many enzymatic reactions in the body involving protein synthesis and carbohydrate metabolism (at least 300 enzymatic reactions require Magnesium carbonate). Actions on lipoprotein lipase have been found to be important in reducing serum cholesterol and on sodium/potassium ATPase in promoting polarization (eg, neuromuscular functioning).
Absorption
Oral: Primary site of absorption of the Magnesium carbonate cation is in the distal small intestine; some insignificant absorption occurs in the colon (Ranade 2001)
Excretion
Urine (almost exclusively) (Ranade 2001)
Protein Binding
~ 33% bound to albumin (Ranade 2001)
References
- DailyMed. "MAGNESIUM CARBONATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- EPA Safer Choice. "EPA Safer Chemical Ingredients Classification: Safer Choice of the U.S. Environmental Protection Agency (EPA) helps consumers, businesses, and purchasers find products that perform and are safer for human health and the environment. This classification is created based on the use classes of each chemical ingredient from the EPA Safer Choice.". https://www.epa.gov/saferchoice (accessed September 17, 2018).
- EPA DSStox. "Magnesium carbonate (1:1): DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". https://comptox.epa.gov/dashboard/ds... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Magnesium carbonate are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Magnesium carbonate. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
