What is Medigesic Plus?
Medigesic Plus contains a combination of Acetaminophen (Medigesic Plus), Butalbital (Medigesic Plus), and Medigesic Plus Acetaminophen (Medigesic Plus) is a pain reliever and fever reducer. Butalbital (Medigesic Plus) is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache. Medigesic Plus is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.
Medigesic Plus is used to treat tension headaches that are caused by muscle contractions.
Medigesic Plus may also be used for purposes not listed in this medication guide.
Medigesic Plus indications
Medigesic Plus is indicated for the relief of the symptom complex of tension (or muscle contraction) headache.
Evidence supporting the efficacy and safety of Medigesic Plus in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because Butalbital (Medigesic Plus) is habit-forming and potentially abusable.
How should I use Medigesic Plus?
Use Medigesic Plus as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Medigesic Plus by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- If you have been taking Medigesic Plus regularly or for longer than a few weeks, do not suddenly stop taking it without checking with your doctor. Your doctor may need to gradually lower your dose.
- If you miss a dose of Medigesic Plus and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Medigesic Plus.
Uses of Medigesic Plus in details
This combination medication is used to treat tension headaches. Acetaminophen (Medigesic Plus) helps to decrease the pain from the headache. Medigesic Plus helps increase the effects of Acetaminophen (Medigesic Plus). Butalbital (Medigesic Plus) is a sedative that helps to decrease anxiety and cause sleepiness and relaxation.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This medication may also be used to treat migraine headaches.
How to use G-1
Take this medication by mouth with or without food as directed by your doctor, usually every 4 hours as needed.
If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
The dosage is based on your medical condition, age, and response to treatment. This medication works best if it is used as the first signs of a headache occur. If you wait until the headache has worsened, the medication may not work as well.
This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as nausea/vomiting, mental/mood changes, seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions right away.
Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.
Tell your doctor if you notice increased use of this medication, a worsening of headaches, an increase in the number of headaches, the medication not working as well, or use of this medication for more than 2 headache episodes a week. Do not take more than recommended. Your doctor may need to change your medication and/or add a separate medication to prevent the headaches.
Medigesic Plus description
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Medigesic Plus&
Medigesic Plus dosage
Medigesic Plus Dosage
Generic name: Butalbital (Medigesic Plus) 50mg, Acetaminophen (Medigesic Plus) 325mg, Medigesic Plus 40mg
Dosage form: tablet
See also:
- Medigesic Plus Capsules capsule
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
One or 2 tablets every 4 hours as needed. Total daily dosage should not exceed 6 tablets.
Extended and repeated use of Medigesic Plus is not recommended because of the potential for physical dependence.
More about Medigesic Plus (Acetaminophen (Medigesic Plus) / Butalbital (Medigesic Plus) / Medigesic Plus)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 106 Reviews - Add your own review/rating
Consumer resources
- Medigesic Plus
- Medigesic Plus capsules and tablets
- Medigesic Plus
Oral (Advanced Reading)
- Other brands: Esgic, Zebutal, Margesic, Vanatol LQ, More (13) »
Professional resources
- Medigesic Plus (FDA)
- Medigesic Plus Capsules (FDA)
Other formulations
- Medigesic Plus with Codeine
Related treatment guides
- Headache
Medigesic Plus interactions
See also:
What other drugs will affect Medigesic Plus?
This medication alters the bioavailability of any drug, absorption depends on pH (ketoconazole, iron salts, etc.). Medigesic Plus slows down the elimination of drugs metabolized in the liver by microsomal oxidation (warfarin, diazepam, phenytoin, etc.).
Medigesic Plus enhances the action of coumarin and diphenine, does not change - NSAIDs. This drug increases (relative) the concentration of clarithromycin in the blood; may increases the leukopenic and thrombocytopenic effects of depressants hematopoiesis drugs. Substance for intravenous infusion is compatible only with saline and dextrose (using other solvents may decrease the stability of omeprazole due to changes in pH of infusion medium).
Medigesic Plus side effects
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What are the possible side effects of Medigesic Plus?
Frequently Observed: The most frequently reported adverse reactions are drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling.
Infrequently Observed: All adverse events tabulated below are classified as infrequent.
Central Nervous System: headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, sluggishness, seizure. Mental confusion, excitement or depression can also occur due to intolerance, particularly in elderly or debilitated patients, or due to overdosage of Butalbital (Medigesic Plus).
Autonomic Nervous System: dry mouth, hyperhidrosis.
Gastrointestinal: difficulty swallowing, heartburn, flatulence, constipation.
Cardiovascular: tachycardia.
Musculoskeletal: leg pain, muscle fatigue.
Genitourinary: diuresis.
Miscellaneous:pruritus, fever, earache, nasal congestion, tinnitus, euphoria, allergic reactions.
Several cases of dermatological reactions, including toxic epidermal necrolysis and erythema multiforme, have been reported.
The following adverse drug events may be borne in mind as potential effects of the components of this product. Potential effects of high dosage are listed in the OVERDOSAGE section.
Acetaminophen (Medigesic Plus): allergic reactions, rash, thrombocytopenia, agranulocytosis.
Medigesic Plus: cardiac stimulation, irritability, tremor, dependence, nephrotoxicity, hyperglycemia.
Medigesic Plus contraindications
See also:
What is the most important information I should know about Medigesic Plus?
Medigesic Plus is contraindicated under the following conditions:
− Hypersensitivity or intolerance to any component of this product.
− Patients with porphyria.
Active ingredient matches for Medigesic Plus:
Acetaminophen/Butalbital/Caffeine
Unit description / dosage (Manufacturer) | Price, USD |
Capsule; Oral; Acetaminophen 325 mg; Butalbital 50 mg; Caffeine 40 mg | |
List of Medigesic Plus substitutes (brand and generic names): | |
Medigesic Oral | |
Minotal | |
Miudol | |
Molie | |
Mygracet | |
Natural Caffeinum | |
Neopharm (Australia, Georgia) | |
Nix Nap | |
No Doz (Australia, New Zealand, United States) | |
No Doz Maximum Strength | |
No-Doz | |
Tablet; Oral; Caffeine 200 mg | |
Nodaca | |
NoDoz | |
NoDoz Maximum Strength | |
Nodoz Maximum Strength Caplets | |
Nonbac | |
NOVALDON | |
Nymusa (Latvia, Lithuania) | |
Odrinil | |
Orbivan | |
Overtime | |
Pacaps | |
Pep-Back | |
Tablet; Oral; Caffeine 100 mg | |
Pep-Back Peak Performance | |
Pep-back Peak Performance tablet, film coated 200 mg/1 (Alva Amco Pharmacal Companies, Inc. (US)) | |
Pep-Back ReCharge | |
Pep-Back Ultra | |
Pep-back Ultra tablet, film coated 200 mg/1 (Alva Amco Pharmacal Companies, Inc. (US)) | |
Percoffedrinol N (Luxembourg) | |
Percutafeine (Argentina, Luxembourg) | |
Gel; Local; Caffeine 5% (Asta medica) | |
Percutaféine (France, Vietnam) | |
Gel; Local; Caffeine 5% | |
Gel; Local; Caffeine 5% | |
Percutafeine Gel (Vietnam) | |
Percutafeine Gel 5 % x 1 tube 200 mL | |
Peyona (Austria, Czech Republic, Denmark, Hungary, Ireland, Portugal, Romania, Spain, United Kingdom) | |
Peyona 20mg/ml (Austria, Hungary, Switzerland) | |
Pharmagesic | |
Phenfree | |
Capsule; Oral; Caffeine 100 mg | |
Phensal | |
Pro (Malta, Taiwan) | |
Pro / Y.C. 10 mg/1 g x 1 g (Dunhall) | |
Pro / Y.C. 10 mg/1 g x 10 g (Dunhall) | |
Pro / Y.C. 10 mg/1 g x 20 g (Dunhall) | |
Pro / Y.C. 10 mg/1 g x 40 g (Dunhall) | |
Pro Plus (Malta) | |
Pro-Plus (United Kingdom, Ireland) | |
Tablet; Oral; Caffeine 50 mg (Roche consumer) | |
See 426 substitutes for Medigesic Plus |
References
- DailyMed. "CAFFEINE; ERGOTAMINE TARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "ASPIRIN; BUTALBITAL; CAFFEINE; CODEINE PHOSPHATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "ACETAMINOPHEN; ASPIRIN; CAFFEINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Medigesic Plus are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Medigesic Plus. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yetConsumer reported age
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Information checked by Dr. Sachin Kumar, MD Pharmacology