Mucotroy warnings
After proper administration of this medicine (acetylcysteine), an increased volume of liquified bronchial secretions may occur. When cough is inadequate, the airway must be maintained open by mechanical suction if necessary. Where there is a mechanical block due to foreign body or local accumulation, the airway should be cleared by endotracheal aspiration, with or without bronchoscopy. Asthmatics under treatment with this medicine should be watched carefully. Most patients with bronchospasm are quickly relieved by the use of a bronchodilator given by nebulization. If bronchospasm progresses, the medication should be discontinued immediately.
With the administration of this medicine, the patient may observe initially a slight disagreeable odor that is soon not noticeable. With a face mask there may be stickiness on the face after nebulization. This is easily removed by washing with water.
Under certain conditions, a color change may occur in this medicine in the opened bottle. The light purple color is the result of a chemical reaction which does not significantly affect safety or mucolytic effectiveness of this medicine.
Continued nebulization of this medicine solution with a dry gas will result in an increased concentration of the drug in the nebulizer because of evaporation of the solvent. Extreme concentration may impede nebulization and efficient delivery of the drug. Dilution of the nebulizing solution with appropriate amounts of Sterile Water for Injection, USP, as concentration occurs, will obviate this problem.
Mucotroy precautions
Bronchial asthma; discontinue upon occurence of bronchospasm. Childn <6 yr & infant, pregnancy & lactation. Granule/dry syr: Patients w/ diabetes or under low-calorie diet.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
