Dosage of Neloren in details
Neloren Dosage
Generic name: Neloren HYDROCHLORIDE 300mg in 1mL
Dosage form: injection, solution
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
If significant diarrhea occurs during therapy, this antibacterial should be discontinued.
INTRAMUSCULAR
Adults
Serious infections—600 mg (2 mL) intramuscularly every 24 hours. More severe infections—600 mg (2 mL) intramuscularly every 12 hours or more often.
Pediatric patients over 1 month of age
Serious infections—one intramuscular injection of 10 mg/kg (5 mg/lb) every 24 hours. More severe infections—one intramuscular injection of 10 mg/kg (5 mg/lb) every 12 hours or more often.
INTRAVENOUS
Adults
The intravenous dose will be determined by the severity of the infection. For serious infections doses of 600 mg of Neloren (2 mL of Neloren) to 1 gram are given every 8 to 12 hours. For more severe infections these doses may have to be increased. In life-threatening situations daily intravenous doses of as much as 8 grams have been given.
Intravenous doses are given on the basis of 1 gram of Neloren diluted in not less than 100 mL of appropriate solution and infused over a period of not less than one hour.
Dose | Vol. Diluent | Time |
---|---|---|
600 mg | 100 mL | 1 hr |
1 gram | 100 mL | 1 hr |
2 grams | 200 mL | 2 hr |
3 grams | 300 mL | 3 hr |
4 grams | 400 mL | 4 hr |
These doses may be repeated as often as required to the limit of the maximum recommended daily dose of 8 grams of Neloren.
Pediatric patients over 1 month of age
10 to 20 mg/kg/day (5 to 10 mg/lb/day) depending on the severity of the infection may be infused in divided doses as described above for adults.
NOTE: Severe cardiopulmonary reactions have occurred when this drug has been given at greater than the recommended concentration and rate.
SUBCONJUNCTIVAL INJECTION
0.25 mL (75 mg) injected subconjunctivally will result in ocular fluid levels of antibacterial (lasting for at least 5 hours) with MICs sufficient for most susceptible pathogens.
Patients with diminished renal function
When therapy with Neloren is required in individuals with severe impairment of renal function, an appropriate dose is 25 to 30% of that recommended for patients with normally functioning kidneys.
More about Neloren (Neloren)
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Consumer resources
- Neloren
- Neloren (Advanced Reading)
Professional resources
- Neloren (AHFS Monograph)
- Neloren (FDA)
Related treatment guides
- Bacterial Infection
- Conjunctivitis, Bacterial
What other drugs will affect Neloren?
Before receiving Neloren, tell your doctor if you are also using erythromycin (E-Mycin, E.E.S., Ery-Tab, Erythrocin, and others).
There may be other drugs that can interact with Neloren. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Neloren interactions
BCG (Intravesical): Antibiotics may diminish the therapeutic effect of BCG (Intravesical). Avoid combination
BCG Vaccine (Immunization): Antibiotics may diminish the therapeutic effect of BCG Vaccine (Immunization). Monitor therapy
Cholera Vaccine: Antibiotics may diminish the therapeutic effect of Cholera Vaccine. Management: Avoid cholera vaccine in patients receiving systemic antibiotics, and within 14 days following the use of oral or parenteral antibiotics. Avoid combination
Doxofylline: Neloren may increase the serum concentration of Doxofylline. Monitor therapy
Erythromycin (Systemic): May diminish the therapeutic effect of Neloren. Avoid combination
Kaolin: May decrease the absorption of Lincosamide Antibiotics. Monitor therapy
Lactobacillus and Estriol: Antibiotics may diminish the therapeutic effect of Lactobacillus and Estriol. Monitor therapy
Mecamylamine: Lincosamide Antibiotics may enhance the neuromuscular-blocking effect of Mecamylamine. Avoid combination
Neuromuscular-Blocking Agents: Lincosamide Antibiotics may enhance the neuromuscular-blocking effect of Neuromuscular-Blocking Agents. Monitor therapy
Sodium Picosulfate: Antibiotics may diminish the therapeutic effect of Sodium Picosulfate. Management: Consider using an alternative product for bowel cleansing prior to a colonoscopy in patients who have recently used or are concurrently using an antibiotic. Consider therapy modification
Typhoid Vaccine: Antibiotics may diminish the therapeutic effect of Typhoid Vaccine. Only the live attenuated Ty21a strain is affected. Management: Vaccination with live attenuated typhoid vaccine (Ty21a) should be avoided in patients being treated with systemic antibacterial agents. Use of this vaccine should be postponed until at least 3 days after cessation of antibacterial agents. Consider therapy modification
References
- FDA/SPL Indexing Data. "BOD072YW0F: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).
- MeSH. "Protein Synthesis Inhibitors". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
- European Chemicals Agency - ECHA. "lincomycin: The European Chemicals Agency (ECHA) is an agency of the European Union which is the driving force among regulatory authorities in implementing the EU's groundbreaking chemicals legislation for the benefit of human health and the environment as well as for innovation and competitiveness.". https://echa.europa.eu/ (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Neloren are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Neloren. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported frequency of use
How frequently do I need to take Neloren?It was reported by ndrugs.com website users that Neloren should ideally be taken Once in a day as the most common frequency of the Neloren. You should you adhere strictly to the instructions and guidelines provided by your doctor on how frequently this Neloren should be taken. Get another patient's view on how frequent the capsule should be used by clicking here.
Users | % | ||
---|---|---|---|
Once in a day | 1 | 100.0% |
Consumer reported doses
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Information checked by Dr. Sachin Kumar, MD Pharmacology