What happens if I overdose Nidelon?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.
Proper storage of Nidelon:
Nidelon is usually handled and stored by a health care provider. If you are using Nidelon at home, store Nidelon as directed by your pharmacist or health care provider. Keep Nidelon out of the reach of children and away from pets.
Overdose of Nidelon in details
No information provided.
What should I avoid while taking Nidelon?
For at least 48 hours after your injection, avoid jogging, strenuous activity, or high-impact sports such as soccer or tennis. Also avoid weight-bearing activity or standing for longer than 1 hour at a time. Ask your doctor how long to wait before you resume these activities.
Nidelon warnings
- Do not concomitantly use disinfectants containing quaternary ammonium salts for skin preparation because Nidelon can precipitate in their presence.
- Anaphylactoid and allergic reactions have been reported with this product. See Adverse Events Section for more detail.
- Transient increases in inflammation in the injected knee following Nidelon® injection in some patients with inflammatory arthritis such as rheumatoid arthritis or gouty arthritis have been reported.
- Patients should be carefully examined prior to administration to determine signs of acute inflammation, and the physician should evaluate whether Nidelon® treatment should be initiated when objective signs of inflammation are present.
What should I discuss with my healthcare provider before taking Nidelon?
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For Nidelon, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to Nidelon or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of Nidelon injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
No information is available on the relationship of age to the effects of Nidelon injection in geriatric patients.
Breast Feeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of Nidelon. Make sure you tell your doctor if you have any other medical problems, especially:
- Allergy to bacterial proteins, gram positive or
- Allergy to hyaluronate preparations or
- Skin or knee joint infections or other problems at the place where the injection is to be given—Should not be given in patients with these conditions.
- Joint effusion (too much fluid in the knees)—Patients with this condition should be treated first before receiving Nidelon.
Nidelon precautions
Long-term viscoelastic supplementation with Nidelon in synovial joints other than the knee and shoulder can be used only in cases appropriate for joint replacement. Nidelon should only be used by qualified persons who are familiar with its use. The general precautions for intra-articular injections should be observed and, particularly, care should be taken to ensure that the site of injection is aseptic.
Nidelon may worsen local inflammation in patients with osteoarthritis who present joint inflammation. Therefore, it is advisable to administer Nidelon after the local symptom has been alleviated.
Local pain may rarely occur after administration of Nidelon. To avoid pain after the injection, an instruction should be given to keep the local site still after the injection has been made.
Nidelon must be injected strictly into the intra-articular space otherwise it may cause pain. Avoid injection into a blood vessel or surrounding tissues.
Nidelon must be administered with caution to patients with a history of hypersensitivity to drugs and to patients with liver failure or impairment.
Do not concomitantly use disinfectants containing quaternary ammonium salts.
Use in pregnancy & lactation: Although no teratogenic effects have been detected in animals, its safety in pregnant women has not been established. It is therefore recommended to administer Nidelon with caution to pregnant women or women suspected of being pregnant. Sodium hyaluronate is excreted in milk of animals treated, so it is recommended to discontinue breastfeeding during treatment.
Use in children: Since the safety of Nidelon has not been established in children, it must be administered with caution to these patients.
Use in the
Elderly: Nidelon must be administered with caution, since physiological functions are usually reduced in these patients.
What happens if I miss a dose of Nidelon?
Call your doctor for instructions if you miss an appointment for your Nidelon.
References
- DrugBank. "HYALURONIC ACID". http://www.drugbank.ca/drugs/DB08818 (accessed September 17, 2018).
- MeSH. "Adjuvants, Immunologic". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
