Optomycin Eye Drops Uses

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What is Optomycin Eye Drops?

Optomycin Eye Drops belongs to the family of medicines called antibiotics. Optomycin Eye Drops ophthalmic preparations are used to treat infections of the eye. Optomycin Eye Drops may be given alone or with other medicines that are taken by mouth for eye infections.

Optomycin Eye Drops is available only with your doctor's prescription.

Optomycin Eye Drops indications

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Optomycin Eye Drops should be used only in those serious infections for which less potentially dangerous drugs are ineffective or contraindicated. Bacteriological studies should be performed to determine the causative organisms and their sensitivity to Optomycin Eye Drops.

Optomycin Eye Drops, 1% (Optomycin Eye Drops Ophthalmic Ointment, USP) is indicated for the treatment of surface ocular infections involving the conjunctiva and/or cornea caused by Optomycin Eye Drops-susceptible organisms.

The particular antiinfective drug in this product is active against the following common bacterial eye pathogens:

Staphylococcus aureus

Streptococcus, including Streptococcus pneumoniae

Escherichia coli

Haemophilus influenzae

Klebsiella/Enterobacter species

Moraxella lucunata

(Morax-Axenfeld bacillus)

Neisseria species

This product does not provide adequate coverage against:

Pseudomonas aeruginosa

Serratia marcescens

How should I use Optomycin Eye Drops?

Use Optomycin Eye Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Optomycin Eye Drops.

Uses of Optomycin Eye Drops in details

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Use: Labeled Indications

Serious infections: Treatment of serious infections, including cystic fibrosis exacerbations, bacterial meningitis, and bacteremia, caused by Chlamydiaceae, Haemophilus influenzae, Rickettsia, Salmonella spp. (acute infections), and other organisms when other less toxic agents are ineffective or contraindicated.

Guideline recommendations: Optomycin Eye Drops may be considered for use as an alternative agent to doxycycline in the treatment of tickborne rickettsial diseases (eg, Rocky Mountain spotted fever [RMSF]); however, epidemiologic studies suggest that Optomycin Eye Drops-treated patients with RMSF are at a higher risk of death compared to tetracycline-treated patients. In addition, Optomycin Eye Drops is not effective in the treatment of human ehrlichiosis or anaplasmosis, therefore, use with caution in the empiric treatment of tickborne rickettsial diseases (CDC [Biggs 2016]).

Optomycin Eye Drops description

Each 100 g contains Chloramphenicol 1 g.

Optomycin Eye Drops dosage

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Optomycin Eye Drops Dosage

Generic name: Optomycin Eye Drops

Dosage form: ophthalmic ointment

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

A small amount of ointment placed in the lower conjunctival sac every three hours, or more frequently if deemed advisable by the prescribing physician. Administration should be continued day and night the first 48 hours, after which the interval between applications may be increased. Treatment should be continued for at least 48 hours after the eye appears normal.

More about Chloromycetin Ophthalmic (Optomycin Eye Drops ophthalmic)

Consumer resources

Professional resources

Other formulations

Optomycin Eye Drops interactions

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Alcohol (Ethyl): Optomycin Eye Drops (Systemic) may enhance the adverse/toxic effect of Alcohol (Ethyl). Monitor therapy

Barbiturates: Optomycin Eye Drops (Systemic) may decrease the metabolism of Barbiturates. Barbiturates may increase the metabolism of Optomycin Eye Drops (Systemic). Monitor therapy

BCG (Intravesical): Antibiotics may diminish the therapeutic effect of BCG (Intravesical). Avoid combination

BCG (Intravesical): Myelosuppressive Agents may diminish the therapeutic effect of BCG (Intravesical). Avoid combination

BCG Vaccine (Immunization): Antibiotics may diminish the therapeutic effect of BCG Vaccine (Immunization). Monitor therapy

Carbocisteine: Optomycin Eye Drops (Systemic) may enhance the adverse/toxic effect of Carbocisteine. Specifically, Optomycin Eye Drops may enhance adverse effects of alcohol that is present in liquid formulations of carbocisteine-containing products. Monitor therapy

CefTAZidime: Optomycin Eye Drops (Systemic) may diminish the therapeutic effect of CefTAZidime. Management: Consider using a different combination of antimicrobials, especially if bactericidal activity is desired. If these agents are combined, monitor for reduced antimicrobial effectiveness and/or therapeutic failure. Consider therapy modification

Optomycin Eye Drops (Ophthalmic): May enhance the adverse/toxic effect of Myelosuppressive Agents. Monitor therapy

Cholera Vaccine: Antibiotics may diminish the therapeutic effect of Cholera Vaccine. Management: Avoid cholera vaccine in patients receiving systemic antibiotics, and within 14 days following the use of oral or parenteral antibiotics. Avoid combination

Cladribine: May enhance the myelosuppressive effect of Myelosuppressive Agents. Avoid combination

CloZAPine: Myelosuppressive Agents may enhance the adverse/toxic effect of CloZAPine. Specifically, the risk for neutropenia may be increased. Monitor therapy

CycloSPORINE (Systemic): Optomycin Eye Drops (Systemic) may increase the serum concentration of CycloSPORINE (Systemic). Management: Cyclosporine dose reductions will likely be required with initiation of concurrent Optomycin Eye Drops. Monitor cyclosporine concentrations and response closely following initiation and/or discontinuation of Optomycin Eye Drops. Consider therapy modification

Deferiprone: Myelosuppressive Agents may enhance the neutropenic effect of Deferiprone. Management: Avoid the concomitant use of deferiprone and myelosuppressive agents whenever possible. If this combination cannot be avoided, monitor the absolute neutrophil count more closely. Consider therapy modification

Dipyrone: May enhance the adverse/toxic effect of Myelosuppressive Agents. Specifically, the risk for agranulocytosis and pancytopenia may be increased Avoid combination

Fosphenytoin: May decrease the serum concentration of Optomycin Eye Drops (Systemic). Fosphenytoin may increase the serum concentration of Optomycin Eye Drops (Systemic). Optomycin Eye Drops (Systemic) may increase the serum concentration of Fosphenytoin. Monitor therapy

Lactobacillus and Estriol: Antibiotics may diminish the therapeutic effect of Lactobacillus and Estriol. Monitor therapy

Mesalamine: May enhance the myelosuppressive effect of Myelosuppressive Agents. Monitor therapy

Phenytoin: May decrease the serum concentration of Optomycin Eye Drops (Systemic). Phenytoin may increase the serum concentration of Optomycin Eye Drops (Systemic). Optomycin Eye Drops (Systemic) may increase the serum concentration of Phenytoin. Monitor therapy

Promazine: May enhance the myelosuppressive effect of Myelosuppressive Agents. Monitor therapy

RifAMPin: May increase the metabolism of Optomycin Eye Drops (Systemic). Monitor therapy

Sodium Picosulfate: Antibiotics may diminish the therapeutic effect of Sodium Picosulfate. Management: Consider using an alternative product for bowel cleansing prior to a colonoscopy in patients who have recently used or are concurrently using an antibiotic. Consider therapy modification

Sulfonylureas: Optomycin Eye Drops (Systemic) may decrease the metabolism of Sulfonylureas. Monitor therapy

Tacrolimus (Systemic): Optomycin Eye Drops (Systemic) may increase the serum concentration of Tacrolimus (Systemic). Management: Tacrolimus dose reductions will likely be required with initiation of concurrent Optomycin Eye Drops. Monitor tacrolimus concentrations and response closely following initiation and/or discontinuation of Optomycin Eye Drops. Consider therapy modification

Typhoid Vaccine: Antibiotics may diminish the therapeutic effect of Typhoid Vaccine. Only the live attenuated Ty21a strain is affected. Management: Vaccination with live attenuated typhoid vaccine (Ty21a) should be avoided in patients being treated with systemic antibacterial agents. Use of this vaccine should be postponed until at least 3 days after cessation of antibacterial agents. Consider therapy modification

Vitamin B12: Optomycin Eye Drops (Systemic) may diminish the therapeutic effect of Vitamin B12. Monitor therapy

Vitamin K Antagonists (eg, warfarin): Optomycin Eye Drops (Systemic) may enhance the anticoagulant effect of Vitamin K Antagonists. Optomycin Eye Drops (Systemic) may increase the serum concentration of Vitamin K Antagonists. Monitor therapy

Voriconazole: Optomycin Eye Drops (Systemic) may increase the serum concentration of Voriconazole. Monitor therapy

Optomycin Eye Drops side effects

See also:
What are the possible side effects of Optomycin Eye Drops?

Applies to Optomycin Eye Drops: capsule, powder for solution, suspension

In addition to its needed effects, some unwanted effects may be caused by Optomycin Eye Drops (the active ingredient contained in Optomycin Eye Drops). In the event that any of these side effects do occur, they may require medical attention.

Stop taking Optomycin Eye Drops and get emergency help immediately if any of the following effects occur:

Rare - in babies only

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Optomycin Eye Drops:

Less common:

Rare

Minor Side Effects

Some of the side effects that can occur with Optomycin Eye Drops may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:

Optomycin Eye Drops contraindications

See also:
What is the most important information I should know about Optomycin Eye Drops?

Optomycin Eye Drops Lotion is contraindicated for premature neonates because their skin may be more permeable than full term infants and their liver enzymes may not be sufficiently developed. It is also contraindicated for patients with Norwegian (crusted) scabies due to possible increased absorption. It is also contraindicated for patients with known seizure disorders and for individuals with a known sensitivity to the product or any of its components.

Active ingredient matches for Optomycin Eye Drops:

Chloramphenicol in Philippines.


Unit description / dosage (Manufacturer)Price, USD
Optomycin Eye Drops 0.5 % x 10 mL$ 3.58

List of Optomycin Eye Drops substitutes (brand and generic names):

Optomycin Ear Drops 5 % x 10 mL$ 3.58
Orichlor 30 ml Syrup (Orison Pharmaceuticals)$ 0.03
Osochlor 500 mg Tablet (Osho Pharma Pvt.Ltd.)$ 0.05
Osochlor 250 mg Tablet (Osho Pharma Pvt.Ltd.)$ 0.03
Otiden Chloramphenicol 5 %, Beclomethasone dipropionate0.025 %, Clotrimazole 1 %, Lignocaine 2 %. EAR-DPS / 10ml (BMW Pharmaco India Pvt Ltd)$ 0.36
10ml (BMW Pharmaco India Pvt Ltd)$ 0.36
Otiden 10 ml Drop (BMW Pharmaco India Pvt Ltd)$ 0.04
Otiden Chloramphenicol 5 %, beclomethasone dipropionate0.025 %, clotrimazole 1 %, lignocaine hydrochloride 2 %. EAR DPS / 10ml (BMW Pharmaco India Pvt Ltd)$ 0.46
OTIDEN ear drops 10ml (BMW Pharmaco India Pvt Ltd)$ 0.46
Otosym Chloramphenicol 5 % w/v, Beclomethasone dipropionate0.025 % w/v, Clotrimazole 1 %w/v, Lignocaine hydrochloride2 % w/v. EAR-DPS / 5ml (Symbiosis Labs (P) Ltd.)$ 0.36
5ml (Symbiosis Labs (P) Ltd.)$ 0.36
Otosym Ear 5 ml Drop (Symbiosis Labs (P) Ltd.)$ 0.07
Otosym Chloramphenicol 5 % w/v, beclomethasone dipropionate0.025 % w/v, clotrimazole 1 %w/v, lignocaine hydrochloride2 % w/v. EAR DPS / 5ml (Symbiosis Labs (P) Ltd.)$ 0.36
OTOSYM ear drops 5ml (Symbiosis Labs (P) Ltd.)$ 0.36
Ototic Ear 5 ml Drop (Zest Pharma)$ 0.43
Palmicol 250 mg x 10 x 10's (Cheplapharm)
Palmicol 125 mg/5 mL x 60 mL (Cheplapharm)
Suspension; Oral; Chloramphenicol Palmitate 312.5 mg / ml
Capsule; Oral; Chloramphenicol; Chloramphenicol Palmitate (AHPL)
Injectable; Injection; Chloramphenicol; Chloramphenicol Palmitate (AHPL)
Drops; Oral; Chloramphenicol; Chloramphenicol Palmitate (AHPL)
Ointment; Topical; Chloramphenicol; Chloramphenicol Palmitate (AHPL)
PARAXIN Capsule/ Tablet / 250mg / 10 units (AHPL)$ 0.55
PARAXIN Capsule/ Tablet / 500mg / 6 units (AHPL)$ 0.63
Paraxin 250mg SC-TAB / 10 (AHPL)$ 0.55
Paraxin 250mg CAP / 10 (AHPL)$ 0.55
Paraxin 500mg CAP / 6 (AHPL)$ 0.63

References

  1. DailyMed. "CHLORAMPHENICOL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "chloramphenicol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "chloramphenicol". http://www.drugbank.ca/drugs/DB00446 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Optomycin Eye Drops are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Optomycin Eye Drops. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

1 consumer reported useful

Was the Optomycin Eye Drops drug useful in terms of decreasing the symptom or the disease?
According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
Users%
Useful1
100.0%


Consumer reported price estimates

No survey data has been collected yet


4 consumers reported time for results

To what extent do I have to use Optomycin Eye Drops before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 3 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Optomycin Eye Drops. To get the time effectiveness of using Optomycin Eye Drops drug by other patients, please click here.
Users%
3 days1
25.0%
1 day1
25.0%
1 week1
25.0%
1 month1
25.0%


14 consumers reported age

Users%
6-154
28.6%
1-53
21.4%
< 13
21.4%
30-452
14.3%
> 601
7.1%
16-291
7.1%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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