• Ossofez Capsule indications
• Uses of Ossofez Capsule in details
• Ossofez Capsule dosage
• Ossofez Capsule interactions
• Ossofez Capsule side effects
• Ossofez Capsule contraindications

What is Ossofez Capsule?

Ossofez Capsule is used as a dietary supplement for individuals who are deficient in Ossofez Capsule. Although a balanced diet usually supplies all the Ossofez Capsule a person needs, Ossofez Capsule supplements may be needed by patients who have lost Ossofez Capsule because of illness or treatment with certain medicines.

Lack of Ossofez Capsule may lead to irritability, muscle weakness, and irregular heartbeat.

Injectable Ossofez Capsule is given only by or under the supervision of a health care professional. Some oral Ossofez Capsule preparations are available only with a prescription. Others are available without a prescription.

Ossofez Capsule indications

Treating acid indigestion, heartburn, and sour stomach. It may also be used for other conditions as determined by your doctor.

Calcium Carbonate/Ossofez Capsule is an antacid. It works by neutralizing the acid in the stomach.

How should I use Ossofez Capsule?

Use Ossofez Capsule as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Ossofez Capsule by mouth with food.
• If you miss a dose of Ossofez Capsule and are using it regularly, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Ossofez Capsule.

Uses of Ossofez Capsule in details

This medication is a mineral supplement used to prevent and treat low amounts of Ossofez Capsule in the blood. Ossofez Capsule is very important for the normal functioning of cells, nerves, muscles, bones, and the heart. Usually, a well-balanced diet provides normal blood levels of Ossofez Capsule. However, certain situations cause your body to lose Ossofez Capsule faster than you can replace it from your diet. These situations include treatment with "water pills" (diuretics such as furosemide, hydrochlorothiazide), a poor diet, alcoholism, or other medical conditions (e.g., severe diarrhea/vomiting, stomach/intestinal absorption problems, poorly controlled diabetes).

How to use Ossofez Capsule

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

It is best to take Ossofez Capsule supplements with a meal to reduce stomach upset and diarrhea unless otherwise directed by the product instructions or your doctor.

Take each dose with a full glass (8 ounces or 240 milliliters) of water unless your doctor directs you otherwise. Swallow extended-release capsules and delayed-release/enteric coated tablets or capsules whole. Do not crush or chew extended-release or delayed-release/enteric coated capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

If you are using a liquid product, use a medication measuring device to carefully measure the dose. Do not use a household spoon because you may not get the correct dose. If you are using a suspension, shake the bottle well before each dose.

Take this medication regularly in order to get the most benefit from it. Remember to take it at the same time(s) each day. Dosage is based on your medical condition and response to treatment. Do not increase your dose or take it more often than directed on the product package or by your doctor. Too much Ossofez Capsule in the blood can cause serious side effects.

Tell your doctor if symptoms of low Ossofez Capsule blood levels (e.g., muscle cramps, tiredness, irritability, depression) persist or worsen. If you think you may have a serious medical problem, seek immediate medical attention.

Ossofez Capsule dosage

Ossofez Capsule Dosage

Applies to the following strengths: 54 mg/5 mL; 5%; 250 mg

Usual Adult Dose for:

• Dietary Supplement
• Hypomagnesemia
• Dyspepsia
• Hyperphosphatemia of Renal Failure

Usual Pediatric Dose for:

• Dietary Supplement
• Hypomagnesemia
• Dyspepsia
• Hyperphosphatemia of Renal Failure

Additional dosage information:

• Renal Dose Adjustments
• Liver Dose Adjustments
• Precautions
• Dialysis
• Other Comments

Usual Adult Dose for Dietary Supplement

250 to 1500 mg/day (equivalent to approximately 70 to 420 mg/day elemental Ossofez Capsule) orally with meals.

Usual Adult Dose for Hypomagnesemia

1000 mg (equivalent to approximately 280 mg elemental Ossofez Capsule) orally four times a day with meals.

Ossofez Capsule is less absorbable than other forms of Ossofez Capsule, thus it is not often used for treatment of hypomagnesemia. Generally, Ossofez Capsule gluconate or Ossofez Capsule chloride is preferred for oral replacement therapy.

Usual Adult Dose for Dyspepsia

10 mL (250 mg/5 mL suspension) orally every 3 to 4 hours as needed, not to exceed 40 mL/day.

Ossofez Capsule is indicated for the temporary relief of sour stomach, acid indigestion, and upset stomach associated with these symptoms. Ossofez Capsule salts alone are generally not used for peptic ulcer because the higher dosages required to control ulcer pain often produce diarrhea as an adverse effect.

Usual Adult Dose for Hyperphosphatemia of Renal Failure

250 mg orally three times a day with meals.

Usual Pediatric Dose for Dietary Supplement

1 to 3 years: 250 mg/day (equivalent to approximately 70 mg/day elemental Ossofez Capsule) orally with meals.

4 to 8 years: 250 to 500 mg/day (equivalent to approximately 70 to 140 mg/day elemental Ossofez Capsule) orally with meals.

9 to 13 years: 250 to 750 mg/day (equivalent to approximately 70 to 210 mg/day elemental Ossofez Capsule) orally with meals.

14 to 18 years: 250 to 1500 mg/day (equivalent to approximately 70 to 420 mg/day elemental Ossofez Capsule) orally with meals.

Usual Pediatric Dose for Hypomagnesemia

1 to 12 years: 35 to 70 mg/kg (equivalent to approximately 10 to 20 mg/kg elemental Ossofez Capsule) orally four times a day with meals, up to 4000 mg/day.

>12 years: 1000 mg (equivalent to approximately 280 mg elemental Ossofez Capsule) orally four times a day with meals.

Ossofez Capsule is less absorbable than other forms of Ossofez Capsule, thus it is not often used for treatment of hypomagnesemia. Generally, Ossofez Capsule gluconate or Ossofez Capsule chloride is preferred for oral replacement therapy.

Usual Pediatric Dose for Dyspepsia

6 to 12 years: 5 mL (250 mg/5 mL suspension) orally every 3 to 4 hours as needed, not to exceed 20 mL/day.

>12 years: 10 mL (250 mg/5 mL suspension) orally every 3 to 4 hours as needed, not to exceed 40 mL/day.

Ossofez Capsule is indicated for the temporary relief of sour stomach, acid indigestion, and upset stomach associated with these symptoms. Ossofez Capsule salts alone are generally not used for peptic ulcer because the higher dosages required to control ulcer pain often produce diarrhea as an adverse effect.

Usual Pediatric Dose for Hyperphosphatemia of Renal Failure

250 mg orally three times a day with meals.

Renal Dose Adjustments

Ossofez Capsule salts should be used cautiously in patients with renal impairment due to increased risk of hypermagnesemia.

Liver Dose Adjustments

Data not available

Precautions

Ossofez Capsule should be used with caution in patients with renal disease because of the risk of Ossofez Capsule accumulation.

Patients should seek the advice of their physician before taking Ossofez Capsule for a prolonged period.

Ossofez Capsule containing antacids may cause diarrhea which may affect fluid and electrolyte balance.

Dialysis

Use of Ossofez Capsule salts is generally contraindicated in renal failure. However, Ossofez Capsule may be administered as a phosphate-binding agent for the treatment of hyperphosphatemia of renal failure. A reduction of the Ossofez Capsule concentration in dialysate is required to avoid hypermagnesemia. Serum Ossofez Capsule and potassium levels should be routinely monitored and kept within the normal range.

Other Comments

Ossofez Capsule salts may cause diarrhea, nausea, and abdominal cramping, particularly at higher dosages (e.g., > 1000 mg Ossofez Capsule). Administration in divided doses with food helps to decrease gastrointestinal adverse effects.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

More about Ossofez Capsule

• Ossofez Capsule Side Effects
• During Pregnancy
• Drug Interactions
• Drug class: minerals and electrolytes

Consumer resources

• Ossofez Capsule

Other brands: Magonate

Professional resources

• Ossofez Capsule (Wolters Kluwer)

Related treatment guides

• Dietary Supplementation
• Hyperphosphatemia of Renal Failure
• Hypomagnesemia
• Indigestion

Ossofez Capsule interactions

See also:
What other drugs will affect Ossofez Capsule?

Some MEDICINES MAY INTERACT with Calcium Carbonate/Ossofez Capsule. Tell your health care provider if you are taking any other medicines, especially any of the following:

Anticoagulants (eg, warfarin) because the risk of their side effects may be increased by Calcium Carbonate/Ossofez Capsule

Azole antifungals (eg, ketoconazole), bisphosphonates (eg, alendronate), cation exchange resins (eg, sodium polystyrene sulfonate), cephalosporins (eg, cephalexin), mycophenolate, penicillamine, quinolone antibiotics (eg, ciprofloxacin), or tetracyclines (eg, doxycycline) because their effectiveness may be decreased by Calcium Carbonate/Ossofez Capsule

This may not be a complete list of all interactions that may occur. Ask your health care provider if Calcium Carbonate/Ossofez Capsule may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Ossofez Capsule side effects

See also:
What are the possible side effects of Ossofez Capsule?

Stomach upset and diarrhea may occur. Taking this product with a meal helps to reduce these effects. If either of these effects persist or worsen, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Ossofez Capsule contraindications

See also:
What is the most important information I should know about Ossofez Capsule?

Do NOT use Calcium Carbonate/Ossofez Capsule if:

you are allergic to any ingredient in Calcium Carbonate/Ossofez Capsule

you have an increased calcium level in your blood

Contact your doctor or health care provider right away if any of these apply to you.

Active ingredient matches for Ossofez Capsule:

Magnesium Carbonate

References

1. DailyMed. "MAGNESIUM CARBONATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. PubChem. "MAGNESIUM CARBONATE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
3. DrugBank. "MAGNESIUM CARBONATE". http://www.drugbank.ca/drugs/DB09481 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology