What is Oxybutinine Chloride?
Oxybutinine Chloride is used to treat symptoms of an overactive bladder, such as incontinence (loss of bladder control) or a frequent need to urinate.
Oxybutinine Chloride belongs to the group of medicines called antispasmodics. It helps decrease muscle spasms of the bladder and the frequent urge to urinate caused by these spasms.
Oxybutinine Chloride extended-release tablets is also used to treat children 6 years of age and older who have an overactive bladder caused by a certain nerve disorder (eg, spina bifida).
Oxybutinine Chloride is available only with your doctor's prescription.
Oxybutinine Chloride indications
Oxybutinine Chloride is indicated for the relief of symptoms of bladder instability associated with voiding in patients with neurogenic bladder i.e.: urgency, frequency, leakage, incontinence and dysuria.
How should I use Oxybutinine Chloride?
Use Oxybutinine Chloride as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Oxybutinine Chloride. Talk to your pharmacist if you have questions about this information.
- Oxybutinine Chloride is for external use only. Do not get it in your eyes, nose, or mouth. If you get it in any of these areas, rinse right away with warm water.
- Apply Oxybutinine Chloride to clean, dry, undamaged skin on the stomach, upper arms, shoulders, or thighs. If you apply Oxybutinine Chloride to the stomach, avoid the area around the belly button.
- Application sites may be rotated to decrease the risk of skin reactions. Do not apply Oxybutinine Chloride to other areas of the body.
- Do not apply Oxybutinine Chloride to skin with an open sore, scar, tattoo, or rash, or to an area that is irritated or has been recently shaved. Do not apply it to an area with a skin condition, such as eczema, seborrhea, or psoriasis.
- Do not apply Oxybutinine Chloride to your breasts or genital areas.
- Do not apply Oxybutinine Chloride to areas of the skin that have been treated with oils, lotions, or powders. However, you may use Oxybutinine Chloride with sunscreen.
- Before using Oxybutinine Chloride for the first time, you must prime the pump. Do this by holding the pump upright and pressing down on the pump 4 times. Do not use any of the medicine that comes out of the pump during priming.
- Wash your hands and the application site with mild soap and water before you apply Oxybutinine Chloride. Allow the area to dry completely.
- Place your hand under the pump and press the pump down 3 times or as directed by your doctor. You can also place the pump right over the application site to dispense your dose. Gently rub Oxybutinine Chloride into your skin until it dries. Do not continue to rub after it dries.
- Apply Oxybutinine Chloride right after you dispense your dose from the pump.
- Wash your hands immediately after using Oxybutinine Chloride.
- Do not bathe, swim, shower, exercise, or get the application site wet for at least 1 hour after using Oxybutinine Chloride.
- Be careful not to get Oxybutinine Chloride on another person. If another person may come into contact with the application site, cover the area with clothing after the medicine dries.
- Continue to use Oxybutinine Chloride even if your condition improves. Do not miss any doses.
- If you miss a dose of Oxybutinine Chloride, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Oxybutinine Chloride.
Uses of Oxybutinine Chloride in details
Use: Labeled Indications
Overactive bladder: Treatment of symptoms associated with overactive bladder (eg, urge urinary incontinence, urgency, frequency, urinary leakage, dysuria); treatment of symptoms associated with overactive bladder due to a neurological condition (eg, spina bifida) in patients ≥6 years of age (extended-release tablet only).
Off Label Uses
Primary focal hyperhidrosis
Data from randomized, placebo-controlled trials with limited numbers of patients and of short duration suggest that Oxybutinine Chloride may be beneficial for treatment of primary hyperhidrosis.
Oxybutinine Chloride description
Oxybutinine Chloride is an anticholinergic medication used to relieve urinary and bladder difficulties, including frequent urination and inability to control urination, by decreasing muscle spasms of the bladder. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.
Oxybutinine Chloride dosage
Oxybutinine Chloride Dosage
Generic name: Oxybutinine Chloride CHLORIDE 100mg in 1g
Dosage form: gel
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
The contents of one sachet of Oxybutinine Chloride should be applied once daily to dry, intact skin on the abdomen, upper arms/shoulders, or thighs. Application sites should be rotated. Application of Oxybutinine Chloride should not be made to the same site on consecutive days.
Oxybutinine Chloride is for topical application only and should not be ingested.
More about Oxybutinine Chloride (Oxybutinine Chloride)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 6 Reviews - Add your own review/rating
Consumer resources
- Oxybutinine Chloride
- Oxybutinine Chloride gel
- Oxybutinine Chloride topical
- Oxybutinine Chloride (Advanced Reading)
- Other brands: Ditropan, Oxybutinine Chloride, Oxytrol, Anturol, More (1) »
Professional resources
- Oxybutinine Chloride (FDA)
- Oxybutinine Chloride Chloride (AHFS Monograph)
Related treatment guides
- Dysuria
- Overactive Bladder
- Urinary Incontinence
Oxybutinine Chloride interactions
See also:
What other drugs will affect Oxybutinine Chloride?
The concomitant use of Oxybutinine Chloride with other anticholinergic drugs or with other agents which produce dry mouth, constipation, somnolence (drowsiness), and/or other anticholinergic-like effects may increase the frequency and/or severity of such effects.
Anticholinergic agents may potentially alter the absorption of some concomitantly administered drugs due to anticholinergic effects on gastrointestinal motility. This may be of concern for drugs with a narrow therapeutic index.
Mean Oxybutinine Chloride chloride plasma concentrations were approximately 3–4 fold higher when DITROPAN was administered with ketoconazole, a potent CYP3A4 inhibitor.
Other inhibitors of the cytochrome P450 3A4 enzyme system, such as antimycotic agents (e.g., itraconazole and miconazole) or macrolide antibiotics (e.g., erythromycin and clarithromycin), may alter Oxybutinine Chloride mean pharmacokinetic parameters (i.e., Cmax and AUC). The clinical relevance of such potential interactions is not known. Caution should be used when such drugs are co-administered.
Oxybutinine Chloride side effects
See also:
What are the possible side effects of Oxybutinine Chloride?
Most side effects encountered with Oxybutinine Chloride administration are due to its anticholinergic and antispasmodic activity.
These effects include dizziness, flushing, confusion, clumsiness and palpitations.
Drowsiness, respiratory depression or troubles in breathing can be observed.
Transient blurred vision, urticaria, constipation, xerostomia and anhydrosis are also rarely reported side effects.
Oxybutinine Chloride contraindications
See also:
What is the most important information I should know about Oxybutinine Chloride?
It is contraindicated for patients with intestinal obstruction, toxic megacolon, severe ulcerative colitis, closed angle glaucoma,myasthenia gravis and urinary obstruction.
Active ingredient matches for Oxybutinine Chloride:
List of Oxybutinine Chloride substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Oxi-q (Argentina) | |
| Oxybutynin Hydrochloride | |
References
- DailyMed. "OXYBUTYNIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "oxybutynin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "oxybutynin". http://www.drugbank.ca/drugs/DB01062 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Oxybutinine Chloride are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Oxybutinine Chloride. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
