Peridex oral rinse Uses

How do you administer this medicine?
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What is Peridex oral rinse?

Peridex oral rinse is used to help treat periodontal disease (a disease of your gums), which is caused by bacteria growing beneath the gum line. Peridex oral rinse works by killing the bacteria. Up to eight Peridex oral rinse implants are placed between your teeth and gums in places where the gum has a deep pocket. Your dentist will place the Peridex oral rinse implants after your teeth have been thoroughly cleaned.

Peridex oral rinse is available only with your dentist's prescription.

Peridex oral rinse indications

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For local use of Peridex oral rinse ICPA Health Products: trichomonas coleitis, cervical erosion, itching of the vulva, prevention of sexually transmitted diseases (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis); gingivitis, stomatitis, aphthae, paradont, alveolitis, disinfection of removable dentures, sore throat; postoperative care for patients in ENT and dentistry.

Treatment of wounds, burn wounds and surfaces, disinfection of the patient's skin.

Treatment of surgeons', nurses' hands and operating field before diagnostic manipulation operation.

Disinfection of work surfaces of devices (including thermometers) and equipment which heat treatment is not desirable.

How should I use Peridex oral rinse?

Use Peridex oral rinse liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Peridex oral rinse liquid.

Uses of Peridex oral rinse in details

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Garlic has been used for hardening of the arteries (atherosclerosis) and high blood pressure (hypertension). Consult your doctor for more information if you have heart disease or high blood pressure. Garlic has also been used to prevent tick bites.

Some herbal/dietary supplement products have been found to contain possibly harmful impurities/additives. Check with your pharmacist for more details about the brand you use.

The FDA has not reviewed this product for safety or effectiveness. Consult your doctor or pharmacist for more details.

How to use Peridex oral rinse

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Peridex oral rinse description

Peridex oral rinse mouthwash contains Chlorhexidine digluconate 1% v/v, equivalent to Peridex oral rinse gluconate solution 0.2% w/v. It also contains ethanol, macrogolglycerol hydroxystearate, sorbitol, flavour and water.

Peridex oral rinse dosage

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Usual Adult Dose for Gingivitis

15 mL twice daily after brushing.

Oral rinse should be retained for 30 seconds then expectorated after rinsing.

Usual Adult Dose for Mucositis

15 mL twice daily after brushing.

Oral rinse should be retained for 30 seconds then expectorated after rinsing.

Usual Adult Dose for Periodontitis

Initial: One 2.5 mg chip inserted into a periodontal pocket with probing pocket depth greater than or equal to 5 mm, up to 8 chips in one visit.

Maintenance: Administration is recommended once every 3 months in pockets with remaining probing depth greater than or equal to 5 mm.

Usual Adult Dose for Skin Disinfection, Preoperative

Peridex oral rinse gluconate 2% cloth:

Patient preoperative skin preparation:

Hold package in one hand and lift flap on backside of package with the other hand. Grasp flap at top and pull down to tear flap away and expose foam. Alternatively, using sterile scissors, cut off end seal of package. Transfer contents onto prep table, avoiding contact between cloths and outside of package to reduce risk of cloth contamination. Use the first cloth to prepare the skin area indicated for a moist or dry site, making certain to keep the second cloth where it will not be contaminated. Use the second cloth to prepare larger areas.

DRY SURGICAL SITES: (such as the abdomen or arm): Use one cloth to cleanse each 161 cm2 area (approximately 5 x 5 inches) of skin to be prepared. Vigorously scrub skin back and forth for 3 minutes, completely wetting treatment area, then discard. Allow area to air dry for one minute. Do not rinse.

MOIST SURGICAL SITES: (such as the inguinal fold): Use one cloth to cleanse each 65 cm2 area (approximately 2 x 5 inches) of skin to be prepared. Vigorously scrub skin back and forth for 3 minutes, completely wetting treatment area, then discard. Do not rinse.

Peridex oral rinse gluconate 4% solution:

SURGICAL HAND SCRUB: Do not dilute. Wet hands and forearms with water and scrub for 3 minutes with about 5 ml and a wet brush, paying close attention to the nails, cuticles, and interdigital spaces. Wash for an additional 3 minutes with 5 ml and rinse under running water. Dry thoroughly.

HEALTHCARE PERSONNEL HANDWASH: Do not dilute. Wet hands with water. Dispense about 5 ml into cupped hands and wash in a vigorous manner for 15 seconds. Rinse and dry thoroughly.

PATIENT PREOPERATIVE SKIN PREPARATION: Do not dilute. Apply liberally to surgical site and swab for at least 2 minutes. Dry with a sterile towel. Repeat procedure for an additional 2 minutes and dry with a sterile towel.

SKIN WOUND AND GENERAL SKIN CLEANSING: Do not dilute. Thoroughly rinse the area to be cleaned with water. Apply a minimum amount necessary to cover the skin or would area and wash gently. Rinse again thoroughly.

Usual Pediatric Dose for Gingivitis

The safety and efficacy of Peridex oral rinse gluconate has not been established in patients less than 18 years old. However, the use of Peridex oral rinse gluconate may be appropriate in some situations.

15 mL twice daily after brushing.

Oral rinse should be retained for 30 seconds then expectorated after rinsing.

Usual Pediatric Dose for Mucositis

The safety and efficacy of Peridex oral rinse gluconate has not been established in patients less than 18 years old. However, the use of Peridex oral rinse gluconate may be appropriate in some situations.

15 mL twice daily after brushing.

Oral rinse should be retained for 30 seconds then expectorated after rinsing.

Usual Pediatric Dose for Periodontitis

The safety and efficacy of Peridex oral rinse gluconate has not been established in patients less than 18 years old. However, the use of Peridex oral rinse gluconate may be appropriate in some situations.

Initial: One 2.5 mg chip inserted into a periodontal pocket with probing pocket depth greater than or equal to 5 mm, up to 8 chips in one visit.

Maintenance: Administration is recommended once every 3 months in pockets with remaining probing depth greater than or equal to 5 mm.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Dialysis

No adjustment recommended

Other Comments

Peridex oral rinse topical cloths are not sterile.

Peridex oral rinse topical cloths should not be microwaved.

Peridex oral rinse solution should be used with care in premature infants or infants under 2 months of age. These products may cause irritation or chemical burns.

Peridex oral rinse topical cloths should not be used in premature or low birthweight infants, infants receiving phototherapy, or infants less than 2 months of age. Peridex oral rinse topical cloths and Peridex oral rinse 4% solution should not be used for lumbar punctures or in contact with the meninges, or on open wounds or as a general skin cleanser.

Peridex oral rinse topical cloths and Peridex oral rinse 4% solution should not make contact with the eyes, nose, or mouth. If contact occurs, the affected area should be washed with cold water and a doctor should be contacted.

Peridex oral rinse 4% solution should not be diluted.

Repeated general cleansing of large areas of the body with Peridex oral rinse 4% topical solution should be avoided except when the underlying condition makes it necessary to reduce the bacterial population of the skin.

Peridex oral rinse interactions

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Peridex oral rinse is incompatible with the soap, and detergents containing anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose).

Peridex oral rinse ICPA Health Products is compatible with any medication containing cationic group (cetrimonium bromide, benzalkonium chloride).

Peridex oral rinse side effects

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What are the possible side effects of Peridex oral rinse?

The most common side effects associated with Peridex oral rinse gluconate oral rinses are (1) an increase in staining of teeth and other oral surfaces, (2) an increase in calculus formation; and (3) an alteration in taste perception; see WARNINGS and PRECAUTIONS.

Oral irritation and local allergy-type symptoms have been spontaneously reported as side effects associated with the use of Peridex oral rinse gluconate rinse.

The following oral mucosal side effects were reported during placebo-controlled adult clinical trials: aphthous ulcer, grossly obvious gingivitis, trauma, ulceration, erythema, desquamation, coated tongue, keratinization, geographic tongue, mucocele, and short frenum. Each occurred at a frequency of less than 1.0%.

Among post marketing reports, the most frequently reported oral mucosal symptoms associated with Peridex oral rinse gluconate oral rinse are stomatitis, gingivitis, glossitis, ulcer, dry mouth, hypesthesia, glossal edema, and paresthesia.

Minor irritation and superficial desquamation of the oral mucosa have been noted in patients using Peridex oral rinse gluconate oral rinse.

There have been cases of parotid gland swelling and inflammation of the salivary glands (sialadenitis) reported in patients using Peridex oral rinse gluconate oral rinse.

Peridex oral rinse contraindications

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What is the most important information I should know about Peridex oral rinse?

Peridex oral rinse gluconate oral rinse should not be used by persons who are known to be hypersensitive to Peridex oral rinse gluconate or other formula ingredients.

Active ingredient matches for Peridex oral rinse:

Chlorhexidine


Unit description / dosage (Manufacturer)Price, USD
Liquid; Buccal; Chlorhexidine Gluconate 0.12%
Mouthwash; Buccal; Chlorhexidine Gluconate 0.12%
Peridex Oral Rinse liquid; mouthwash/gargle 0.12 % (3 M Canada Company (Canada))

List of Peridex oral rinse substitutes (brand and generic names):

PERIEX mouthwash 2 % v/v x 160ml (Dent Aids)$ 0.75
Chip; Intra-Periodontal Pocket; 2.5 mg
Mouthwash; Local Oral; Cetylpyridinium Chloride; Chlorhexidine Gluconate (Pharmatrix)
Spray, Local Oral; Cetylpyridinium Chloride; Chlorhexidine Gluconate (Pharmatrix)
Gel; Dental; Chlorhexidine Gluconate
Liquid; Topical; Chlorhexidine Gluconate 0.12%
Gel; Dental; Chlorhexidine Gluconate
Pfizer Obstetric Lotion 1 % x 200 g x 1's (Pfizer consumer)
Lotion; Topical; Chlorhexidine Gluconate 1% (Pfizer consumer)
Sponge; Topical; Chlorhexidine Gluconate 4% (CareFusion)
Solution; Local Oral; Chlorhexidine Gluconate (Altana)
Solution; Topical; Chlorhexidine Gluconate 1.5% (Ucb)
Solution; Udder Wash; Chlorhexidine Acetate 1.2%
Solution; Topical; Chlorhexidine Gluconate 0.5% (Johnson & Johnson)

References

  1. DailyMed. "CHLORHEXIDINE GLUCONATE; ISOPROPYL ALCOHOL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "chlorhexidine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "chlorhexidine". http://www.drugbank.ca/drugs/DB00878 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Peridex oral rinse are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Peridex oral rinse. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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