What is Piperazillin/Tazobactam Teva 4.5g?
Piperazillin/Tazobactam Teva 4.5g and Tazobactam (Piperazillin/Tazobactam Teva 4.5g) injection is used to treat bacterial infections in many different parts of the body.
Piperazillin/Tazobactam Teva 4.5g and Tazobactam (Piperazillin/Tazobactam Teva 4.5g) combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria and preventing their growth. However, Piperazillin/Tazobactam Teva 4.5g and Tazobactam (Piperazillin/Tazobactam Teva 4.5g) will not work for colds, flu, or other virus infections.
Piperazillin/Tazobactam Teva 4.5g and Tazobactam (Piperazillin/Tazobactam Teva 4.5g) is to be given only by or under the direct supervision of your doctor.
Piperazillin/Tazobactam Teva 4.5g indications
Piperazillin/Tazobactam Teva 4.5g is indicated for the treatment of the following systemic and/or local bacterial infections in which susceptible organisms have been detected or are suspected: Lower respiratory tract infections; urinary tract infections (complicated and uncomplicated); intra-abdominal infections; skin and skin structure infections; bacterial septicemia. Polymicrobial infections: Piperazillin/Tazobactam Teva 4.5g is indicated for polymicrobial infections including those where aerobic and anaerobic organisms are suspected (intra-abdominal, skin and skin structure, lower respiratory tract).
Piperazillin/Tazobactam Teva 4.5g, in combination with an aminoglycoside, is indicated for bacterial infections in neutropenic adults or children.
Children Under the Age of 12 Years: In hospitalized children aged 2 to 12 years, Piperazillin/Tazobactam Teva 4.5g is indicated for the treatment of intra-abdominal infections including appendicitis complicated by rupture or abscess, peritonitis, and biliary infections. It has not been evaluated in this indication for pediatric patients below the age of 2 years.
Whilst Piperazillin/Tazobactam Teva 4.5g is indicated only for the conditions listed above, infections caused by Piperazillin/Tazobactam Teva 4.5g susceptible organisms are also amendable to Piperazillin/Tazobactam Teva 4.5g treatment due to its Piperazillin/Tazobactam Teva 4.5g content. Therefore, the treatment of mixed infections caused by Piperazillin/Tazobactam Teva 4.5g susceptible organisms and β-beta lactamase producing organisms susceptible to Piperazillin/Tazobactam Teva 4.5g should not require the addition of another antibiotic.
Piperazillin/Tazobactam Teva 4.5g is particularly useful in the treatment of mixed infections and in presumptive therapy prior to the availability of the results of sensitivity tests because of its broad spectrum of activity.
Piperazillin/Tazobactam Teva 4.5g acts synergistically with aminoglycosides against certain strains of Pseudomonas aeruginosa. Combined therapy has been successful, especially in patients with impaired host defences. Both drugs should be used in full therapeutic doses. As soon as results of culture and susceptibility tests become available, antimicrobial therapy should be adjusted if necessary.
How should I use Piperazillin/Tazobactam Teva 4.5g?
Use Piperazillin/Tazobactam Teva 4.5g as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Piperazillin/Tazobactam Teva 4.5g is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Piperazillin/Tazobactam Teva 4.5g at home, a health care provider will teach you how to use it. Be sure you understand how to use Piperazillin/Tazobactam Teva 4.5g. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Do not use Piperazillin/Tazobactam Teva 4.5g if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Piperazillin/Tazobactam Teva 4.5g, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Piperazillin/Tazobactam Teva 4.5g.
Uses of Piperazillin/Tazobactam Teva 4.5g in details
Use: Labeled Indications
Intra-abdominal infections: Treatment of appendicitis complicated by rupture or abscess and peritonitis caused by beta-lactamase-producing strains of Escherichia coli, Bacteroides fragilis, Bacteroides ovatus, Bacteroides thetaiotaomicron, or Bacteroides vulgatus.
Pelvic infections: Treatment of postpartum endometritis or pelvic inflammatory disease caused by beta-lactamase-producing strains of E. coli.
Pneumonia, community-acquired: Treatment of moderate severity community-acquired pneumonia (CAP) caused by beta-lactamase-producing strains of Haemophilus influenzae.
Pneumonia, hospital-acquired (nosocomial): Treatment of moderate to severe hospital-acquired (nosocomial) pneumonia caused by beta-lactamase-producing strains of Staphylococcus aureus and by Piperazillin/Tazobactam Teva 4.5g-susceptible Acinetobacter baumannii, H. influenzae, Klebsiella pneumoniae, and P. aeruginosa.
Skin and skin structure infections: Treatment of skin and skin structure infections, including cellulitis, cutaneous abscesses, and ischemic/diabetic foot infections caused by beta-lactamase-producing strains of S. aureus.
Off Label Uses
Bite wound infection, treatment (animal or human bite)
Based on the Infectious Diseases Society of America (IDSA) guidelines for the diagnosis and management of skin and soft tissue infections (SSTIs), Piperazillin/Tazobactam Teva 4.5g and Tazobactam (Piperazillin/Tazobactam Teva 4.5g) is an effective and recommended treatment of animal bite wound infections.
Clinical experience supports the utility of Piperazillin/Tazobactam Teva 4.5g and Tazobactam (Piperazillin/Tazobactam Teva 4.5g) in the treatment of human bite wound infections.
Piperazillin/Tazobactam Teva 4.5g description
Each 2.25 g single-dose vial contains Piperazillin/Tazobactam Teva 4.5g sodium equivalent to Piperazillin/Tazobactam Teva 4.5g 2 g and Tazobactam (Piperazillin/Tazobactam Teva 4.5g) sodium equivalent to Tazobactam (Piperazillin/Tazobactam Teva 4.5g) 0.25 g and edetate disodium (dihydrate) (EDTA) 0.5 mg.
Each 4.5 g single-dose vial contains Piperazillin/Tazobactam Teva 4.5g sodium equivalent to Piperazillin/Tazobactam Teva 4.5g 4 g and Tazobactam (Piperazillin/Tazobactam Teva 4.5g) sodium equivalent to Tazobactam (Piperazillin/Tazobactam Teva 4.5g) 0.5 g and edetate disodium (dihydrate) (EDTA) 1 mg.
Piperazillin/Tazobactam Teva 4.5g is an injectable antibacterial combination consisting of the semisynthetic antibiotic Piperazillin/Tazobactam Teva 4.5g sodium and the beta-lactamase inhibitor Tazobactam (Piperazillin/Tazobactam Teva 4.5g) sodium for intravenous administration. Piperazillin/Tazobactam Teva 4.5g sodium is derived from D(-)-a-aminobenzylpenicillin. The chemical name of Piperazillin/Tazobactam Teva 4.5g sodium is sodium (2S, 5R, 6R)-6-[(R)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido] – 3,3 –dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0] heptane – 2 – carboxylate. Piperazillin/Tazobactam Teva 4.5g sodium is a white, crystalline powder. Piperazillin/Tazobactam Teva 4.5g sodium is freely soluble in water, in alcohol, and in methyl alcohol; practically insoluble in ethyl acetate. Tazobactam (Piperazillin/Tazobactam Teva 4.5g) sodium is a derivative of the penicillin nucleus. Chemically, Tazobactam (Piperazillin/Tazobactam Teva 4.5g) is a penicillanic acid sulfone. Its chemical name is sodium (2S-,3S-,5R) – 3 – methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,4,4-dioxide. Tazobactam (Piperazillin/Tazobactam Teva 4.5g) sodium is a white to pale yellow non-hydroscopic crystalline powder.
Piperazillin/Tazobactam Teva 4.5g also contains the following excipients: Piperazillin/Tazobactam Teva 4.5g monohydrate, Tazobactam (Piperazillin/Tazobactam Teva 4.5g), sodium hydrogen carbonate, citric acid (monohydrate), EDTA, water for injections and nitrogen.
Piperazillin/Tazobactam Teva 4.5g dosage
Piperazillin/Tazobactam Teva 4.5g should be administered by intravenous infusion over 30 minutes.
The usual daily dose of Piperazillin/Tazobactam Teva 4.5g for adults is 3.375 g every six hours totaling 13.5 g (12.0 g Piperazillin/Tazobactam Teva 4.5g/1.5 g Tazobactam (Piperazillin/Tazobactam Teva 4.5g)).
Nosocomial Pneumonia
Initial presumptive treatment of patients with nosocomial pneumonia should start with Piperazillin/Tazobactam Teva 4.5g at a dosage of 4.5 g every six hours plus an aminoglycoside, totaling 18.0 g (16.0 g Piperazillin/Tazobactam Teva 4.5g/2.0 g Tazobactam (Piperazillin/Tazobactam Teva 4.5g)). Treatment with the aminoglycoside should be continued in patients from whom Pseudomonas aeruginosa is isolated. If Pseudomonas aeruginosa is not isolated, the aminoglycoside may be discontinued at the discretion of the treating physician.
Due to the in vitro inactivation of the aminoglycoside by beta-lactam antibiotics, Piperazillin/Tazobactam Teva 4.5g and the aminoglycoside are recommended for separate administration. Piperazillin/Tazobactam Teva 4.5g and the aminoglycoside should be reconstituted, diluted, and administered separately when concomitant therapy with aminoglycosides is indicated.
In circumstances where coadministration via Y-site is necessary, reformulated Piperazillin/Tazobactam Teva 4.5g containing EDTA supplied in Galaxy containers is compatible for simultaneous coadministration via Y-site infusion only with the following aminoglycosides under the following conditions:
The following compatibility information does not apply to the Piperazillin/Tazobactam Teva 4.5g (Piperazillin/Tazobactam Teva 4.5g) formulation not containing EDTA. This information does not apply to Piperazillin/Tazobactam Teva 4.5g in vials or bulk pharmacy containers. Refer to the package insert for Piperazillin/Tazobactam Teva 4.5g vials or bulk pharmacy containers for instructions.
| Aminoglycoside | Piperazillin/Tazobactam Teva 4.5g Dose (grams) | Aminoglycoside Concentration Range* (mg/mL) | Acceptable Diluents |
|---|---|---|---|
| Amikacin | 2.25, 3.375, 4.5 | 1.75 – 7.5 | 0.9% Sodium Chloride or 5% Dextrose |
| Gentamicin | 2.25, 3.375, 4.5 | 0.7 – 3.32 | 0.9% Sodium Chloride or 5% Dextrose |
| *The concentration ranges in Table 5 are based on administration of the aminoglycoside in divided doses (10-15 mg/kg/day in two daily doses for amikacin and 3-5 mg/kg/day in three daily doses for gentamicin). Administration of amikacin or gentamicin in a single daily dose or in doses exceeding those stated above via Y-site with Piperazillin/Tazobactam Teva 4.5g containing EDTA has not been evaluated. See package insert for each aminoglycoside for complete Dosage and Administration instructions. | |||
Piperazillin/Tazobactam Teva 4.5g is not compatible with tobramycin for simultaneous coadministration via Y-site infusion. Compatibility of Piperazillin/Tazobactam Teva 4.5g with other aminoglycosides has not been established. Only the concentration and diluents for amikacin or gentamicin with the dosages of Piperazillin/Tazobactam Teva 4.5g listed above have been established as compatible for coadministration via Y-site infusion. Simultaneous coadministration via Y-site infusion in any manner other than listed above may result in inactivation of the aminoglycoside by Piperazillin/Tazobactam Teva 4.5g.
Renal Insufficiency
In patients with renal insufficiency (Creatinine Clearance ≤ 40 mL/min), the intravenous dose of Piperazillin/Tazobactam Teva 4.5g should be adjusted to the degree of actual renal function impairment. In patients with nosocomial pneumonia receiving concomitant aminoglycoside therapy, the aminoglycoside dosage should be adjusted according to the recommendations of the manufacturer. The recommended daily doses of Piperazillin/Tazobactam Teva 4.5g for patients with renal insufficiency are as follows:
| Renal Function (Creatinine Clearance, mL/min) | All Indications (except nosocomial pneumonia) | Nosocomial Pneumonia |
|---|---|---|
| >40 mL/min | 3.375 q 6 h | 4.5 q 6 h |
| 20-40 mL/min* | 2.25 q 6 h | 3.375 q 6 h |
| <20 mL/min* | 2.25 q 8 h | 2.25 q 6 h |
| Hemodialysis** | 2.25 q 12 h | 2.25 q 8 h |
| CAPD | 2.25 q 12 h | 2.25 q 8 h |
| * Creatinine clearance for patients not receiving hemodialysis ** 0.75 g should be administered following each hemodialysis session on hemodialysis days | ||
For patients on hemodialysis, the maximum dose is 2.25 g every twelve hours for all indications other than nosocomial pneumonia and 2.25 g every eight hours for nosocomial pneumonia. Since hemodialysis removes 30% to 40% of the administered dose, an additional dose of 0.75 g Piperazillin/Tazobactam Teva 4.5g should be administered following each dialysis period on hemodialysis days. No additional dosage of Piperazillin/Tazobactam Teva 4.5g is necessary for CAPD patients.
Duration of Therapy
The usual duration of Piperazillin/Tazobactam Teva 4.5g treatment is from seven to ten days. However, the recommended duration of Piperazillin/Tazobactam Teva 4.5g treatment of nosocomial pneumonia is 7 to 14 days. In all conditions, the duration of therapy should be guided by the severity of the infection and the patient's clinical and bacteriological progress.
Pediatric Patients
For children with appendicitis and/or peritonitis 9 months of age or older, weighing up to 40 kg, and with normal renal function, the recommended Piperazillin/Tazobactam Teva 4.5g dosage is 100 mg Piperazillin/Tazobactam Teva 4.5g/12.5 mg Tazobactam (Piperazillin/Tazobactam Teva 4.5g) per kilogram of body weight, every 8 hours. For pediatric patients between 2 months and 9 months of age, the recommended Piperazillin/Tazobactam Teva 4.5g dosage based on pharmacokinetic modeling, is 80 mg Piperazillin/Tazobactam Teva 4.5g/10 mg Tazobactam (Piperazillin/Tazobactam Teva 4.5g) per kilogram of body weight, every 8 hours. Pediatric patients weighing over 40 kg and with normal renal function should receive the adult dose. There are no dosage recommendations for Piperazillin/Tazobactam Teva 4.5g in pediatric patients with impaired renal function.
Piperazillin/Tazobactam Teva 4.5g in Galaxy containers should not be used in pediatric patients who require less than the full adult dose of Piperazillin/Tazobactam Teva 4.5g in order to prevent unintentional overdose. The other available formulations of Piperazillin/Tazobactam Teva 4.5g can be used in this population.
DIRECTIONS FOR USE OF Piperazillin/Tazobactam Teva 4.5g (Piperazillin/Tazobactam Teva 4.5g AND Tazobactam (Piperazillin/Tazobactam Teva 4.5g) INJECTION) IN GALAXY CONTAINERS (PL 2040 PLASTIC)
Piperazillin/Tazobactam Teva 4.5g Injection (PL 2040 Plastic) is to be administered using sterile equipment after thawing to room temperature.
Piperazillin/Tazobactam Teva 4.5g containg EDTA is compatible for co-administration via a Y-site intravenous tube with Lactated Ringer's injection, USP.
Administer by infusion over a period of at least 30 minutes. During the infusion it is desirable to discontinue the primary infusion solution.
Piperazillin/Tazobactam Teva 4.5g should not be mixed with other drugs in a syringe or infusion bottle since compatibility has not been established.
Piperazillin/Tazobactam Teva 4.5g is not chemically stable in solutions that contain only sodium bicarbonate and solutions that significantly alter the pH.
Piperazillin/Tazobactam Teva 4.5g should not be added to blood products or albumin hydrolysates.
Piperazillin/Tazobactam Teva 4.5g interactions
See also:
What other drugs will affect Piperazillin/Tazobactam Teva 4.5g?
The following drug interactions are chosen on the basis of their potential clinical significance:
Aminoglycosides: The mixing of Piperazillin/Tazobactam Teva 4.5g in vitro can result in substantial inactivation of the aminoglycosides.
When Piperazillin/Tazobactam Teva 4.5g is administered together with tobramycin, the AUC, renal clearance and urinary recovery of tobramycin were decreased by 11%, 32% and 38%, respectively. The alterations in the pharmacokinetics of tobramycin when administered in conjunction with Piperazillin/Tazobactam Teva 4.5g may be due to inactivation of tobramycin in the presence of Piperazillin/Tazobactam Teva 4.5g. It has been postulated that penicillin-aminoglycoside complexes form and these complexes are micobiologically inactive and unknown toxicity.
Probenecid: Probenecid administered concomitantly with Piperazillin/Tazobactam Teva 4.5g prolongs the t½ of Piperazillin/Tazobactam Teva 4.5g by 21% and that of Tazobactam (Piperazillin/Tazobactam Teva 4.5g) by 71%.
Heparin, Anticoagulants and Drugs Affecting the Blood: Coagulation parameters should be tested more frequently and monitored regularly during simultaneous administration of high doses of heparin, anticoagulants and Piperazillin/Tazobactam Teva 4.5g that may affect the blood coagulation system or the thrombocyte function.
Vecuronium: Piperazillin/Tazobactam Teva 4.5g when used concomitantly with vecuronium has been implicated in the prolongation of vecuronium's neuromuscular blockade. It is also expected that neuromuscular blockade produced by any of the nondepolarizing muscle muscle relaxants could be prolonged in the presence of Piperazillin/Tazobactam Teva 4.5g.
Methotrexate: Limited data suggest that the clearance of methotrexate is reduced when co-administered with Piperazillin/Tazobactam Teva 4.5g, due to competition for renal secretion. The impact of Tazobactam (Piperazillin/Tazobactam Teva 4.5g) on the elimination of methotrexate has not been evaluated. If Piperazillin/Tazobactam Teva 4.5g and methotrexate are administered concomitantly, serum concentrations of methotrexate as well as signs and symptoms of methotrexate toxicity should be closely monitored.
Drug/Laboratory Test Interactions: As with other penicillins, the administration of Piperazillin/Tazobactam Teva 4.5g may result in a false positive reaction of glucose in the urine using copper-reduction method (Clinitest). It is recommended that glucose tests based on enzymatic glucose oxidase reactions be used.
In patients with renal failure, Piperazillin/Tazobactam Teva 4.5g is reported to cause abnormalities in clotting time, platelet aggregation and prothrombin time that close monitoring of the patient's coagulation tests is recommended.
Piperazillin/Tazobactam Teva 4.5g side effects
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What are the possible side effects of Piperazillin/Tazobactam Teva 4.5g?
Adverse drug reactions reported with Piperazillin/Tazobactam Teva 4.5g are similar to those reported with Piperazillin/Tazobactam Teva 4.5g alone and generally are transient and mild to moderate in severity. Adverse events have been reported in about ≤10% of patients receiving parenteral Piperazillin/Tazobactam Teva 4.5g and have been severe enough to require discontinuance in ≤3% of patients.
The most common frequent adverse effects reported with Piperazillin/Tazobactam Teva 4.5g are gastrointestinal (GI) effects, headache and hypersensitivity reactions.
Hypersensitivity Reactions: Rash, pruritus and fever have been reported in up to 4% of patients receiving Piperazillin/Tazobactam Teva 4.5g. Rare reports of bronchospasm have also been reported.
Gastrointestinal Effects: Diarrhea, nausea, constipation have been reported in up to 11% of patients receiving Piperazillin/Tazobactam Teva 4.5g. Vomiting, dyspepsia, stool changes and abdominal pain can occur in up to 3%, while melena, flatulence, hemorrhage, gastritis, hiccups and ulcerative stomatitis are reported in ≤1% of patients.
Clostridium difficile-associated diarrhea and colitis or antibiotic-associated pseudomembranous colitis have been reported in at least 1 patient receiving Piperazillin/Tazobactam Teva 4.5g. Colitis may occur during or following discontinuance of anti-infective therapy and may range in severity from mild to life-threatening.
Hematologic Effects: Transient leukopenia, neutropenia and thrombocytopenia have been reported in patients receiving Piperazillin/Tazobactam Teva 4.5g for a prolonged period of time (eg, after ≥21 days) and generally were reversible, systemic symptoms (eg, fever, rigors and chills) may also occur in some patients. Epistaxis and purpura have been reported in ≤1% patients.
Hepatic Effects: Transient increases in aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase and bilirubin can occur.
Renal Effects: Increases in serum concentrations of creatinine and blood urea nitrogen (BUN) may be observed. Urinary retention, dysuria, oliguria, hematuria and incontinence have been reported in ≤1% and proteinuria, pyuria, leukorrhea and vaginitis can also occur.
Effect on the Central Nervous System: Headache and insomnia have been reported in up to 7-8%, while agitation, dizziness and anxiety have been reported in ≤2% patients. Tremors, seizures, vertigo, confusion, hallucination, malaise and depression have been reported in ≤1% of patients receiving Piperazillin/Tazobactam Teva 4.5g. Neuromuscular excitability or seizures could occur in higher than recommended doses are given IV, especially in patients with kidney failure.
Local Reactions: Adverse reactions at the injection site have been reported in ≤1% of patients. Adverse local reactions include phlebitis, pain, inflammation, thrombophlebitis and edema.
Other Adverse Effects: Hypertension, chest pain, edema, moniliasis, rhinitis, dyspnea, hypotension, ileus, syncope and rigors have been reported in ≤2% of patients. Tachycardia, bradycardia, heart failure and myocardial infarction have been reported in at most 1%.
Piperazillin/Tazobactam Teva 4.5g contraindications
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What is the most important information I should know about Piperazillin/Tazobactam Teva 4.5g?
Piperazillin/Tazobactam Teva 4.5g and Tazobactam (Piperazillin/Tazobactam Teva 4.5g) for injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or β-lactamase inhibitors.
Active ingredient matches for Piperazillin/Tazobactam Teva 4.5g:
Piperacillin/Tazobactam in Switzerland.
List of Piperazillin/Tazobactam Teva 4.5g substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Piperazillin/Tazobactam-Teva (Switzerland) | |
| Piperbact (Vietnam) | |
| Piperbact 1 Bottle 30 mL | |
| Pipercin (Ireland) | |
| Pipertaz (Peru) | |
| Pipertaz 1's (Great Eastern) | |
| PiperTaz Sandoz (Australia) | |
| Pipertazo (Colombia) | |
| PIPET (India) | |
| Pipetazon (Bulgaria) | |
| Pipetexina (Argentina) | |
| Pipitaz (Austria) | |
| Pipitaz 4,0 g/0,5 g (Austria) | |
| Piplak -TBZ | |
| Piplak -TBZ Piperacillin 4g, Tazobactam500mg VIAL / 1 | |
| PIPLAK-TBZ (India) | |
| 1's (Laksun) | |
| Piplak-TBZ Piperacillin 4g, Tazobactam500mg VIAL / 1 (Laksun) | |
| Piplak-TBZ Piperacillin 4g, Tazobactam500mg VIAL / 1 (Laksun) | |
| Pipmax INJ (India) | |
| Pipmax INJ Piperacillin 4gm, Tazobactam0.5gm VIAL / 1 (KAPL) | $ 3.61 |
| 1's (KAPL) | $ 3.61 |
| PIPMED-T (India) | |
| PIPRA-T (India) | |
| 1's (Moraceae) | $ 6.99 |
| Pipra-T Piperacillin 4 g, tazobactam0.5 g. INJ / 1 (Moraceae) | $ 6.99 |
| Pipra-T Piperacillin 4 g, tazobactam0.5 g. INJ / 1 (Moraceae) | $ 6.99 |
| Piprabac (India) | |
| Piprabac Piperacillin 4g, Tazobactam0.5g INJ / 1 (Positif (Nutron)) | $ 5.90 |
| 1's (Positif (Nutron)) | $ 5.90 |
| Piprafast-T (India) | |
| Piprafast-T Piperacillin 1g, Tazobactam125mg VIAL / 5ml (Invision) | $ 1.33 |
| 5ml (Invision) | $ 1.33 |
| PIPRAGEM-T (India) | |
| PIPRAGRAM-T (India) | |
| 1's (Invision (Ikeirdorf)) | $ 6.01 |
| Pipragram-T Piperacillin 4000 mg, tazobactam 500 mg. INJ / 1 (Invision (Ikeirdorf)) | $ 6.01 |
| Pipragram-T Piperacillin 4000 mg, tazobactam 500 mg. INJ / 1 (Invision (Ikeirdorf)) | $ 6.01 |
| Pipranem (India) | |
| Pipranem Piperacillin, Tazobactam INJ / 2.25g (Taj Pharma) | $ 4.75 |
| Pipranem Piperacillin, Tazobactam INJ / 4.5g (Taj Pharma) | $ 8.14 |
| 1's (Taj Pharma) | $ 4.75 |
| PIPRAPEN-T (India) | |
| 1's (FDC (Proxima)) | $ 1.80 |
| Piprapen-T Piperacillin 4g, Tazobactam0.5g VIAL / 1 (FDC (Proxima)) | $ 3.61 |
| Piprapen-T Piperacillin 2g, Tazobactam250mg VIAL / 1 (FDC (Proxima)) | $ 1.80 |
| Piprapen-T Piperacillin 4g, Tazobactam0.5g VIAL / 1 (FDC (Proxima)) | $ 3.61 |
| Piprapen-T Piperacillin 2g, Tazobactam250mg VIAL / 1 (FDC (Proxima)) | $ 1.80 |
| PIPRAS-T (India) | |
| 1's (Shreshtha) | $ 5.42 |
| Pipras-T Piperacillin 2 g, tazobactam0.25 g. VIAL / 1 (Shreshtha) | $ 3.61 |
| Pipras-T Piperacillin 4 g, tazobactam0.5 g. VIAL / 1 (Shreshtha) | $ 5.42 |
| Pipras-T Piperacillin 2 g, tazobactam0.25 g. VIAL / 1 (Shreshtha) | $ 3.61 |
| Pipras-T Piperacillin 4 g, tazobactam0.5 g. VIAL / 1 (Shreshtha) | $ 5.42 |
See 1079 substitutes for Piperazillin/Tazobactam Teva 4.5g | |
References
- PubChem. "piperacillin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "Tazobactam". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Tazobactam". http://www.drugbank.ca/drugs/DB01606 (accessed September 17, 2018).
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| Users | % | ||
|---|---|---|---|
| 16-29 | 1 | 100.0% | |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
