Potassium Iodide Yamazen Seiyaku Uses

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What is Potassium Iodide Yamazen Seiyaku?

Potassium Iodide Yamazen Seiyaku is the potassium salt form of iodide, a naturally occurring substance.

Potassium Iodide Yamazen Seiyaku can be used as an expectorant to thin mucus and loosen congestion in your chest and throat.

Potassium Iodide Yamazen Seiyaku is used in people with chronic breathing problems that can be complicated by thick mucus in the respiratory tract, such as asthma, chronic bronchitis, or emphysema.

Potassium Iodide Yamazen Seiyaku may also be used for purposes not listed in this medication guide.

Potassium Iodide Yamazen Seiyaku indications

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Potassium Iodide Yamazen Seiyaku is oral antithyroid agent. Potassium Iodide Yamazen Seiyaku is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution. (radiation poisoning;)

How should I use Potassium Iodide Yamazen Seiyaku?

Use Potassium Iodide Yamazen Seiyaku solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Potassium Iodide Yamazen Seiyaku solution.

Uses of Potassium Iodide Yamazen Seiyaku in details

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Use: Labeled Indications

Antidote: Block thyroidal uptake of radioactive isotopes of iodine in a nuclear radiation emergency.

Expectorant: Expectorant for the symptomatic treatment of chronic pulmonary diseases complicated by mucous.

Off Label Uses

Graves hyperthyroidism (following radioactive iodine therapy)

Data from a retrospective study suggest that Potassium Iodide Yamazen Seiyaku may be beneficial in select patients with Graves hyperthyroidism (eg, those who would be candidates for but are allergic to antithyroid drugs) in order to shorten the duration of hyperthyroidism after receiving radioactive iodine therapy.

Thyroid gland protection during radiopharmaceutical use

Based on the European Association of Nuclear Medicine (EANM) procedure guidelines for 131 I-meta-iodobenzylguanidine (131 I-mIBG) therapy, Potassium Iodide Yamazen Seiyaku is effective and recommended when given as thyroid gland protection during radiopharmaceutical use.

Thyrotoxic crisis/thyroid storm

Based on the American Thyroid Association and American Association of Clinical Endocrinologists guidelines for the diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis, Potassium Iodide Yamazen Seiyaku given to adults for thyrotoxic crisis/thyroid storm is effective and recommended in the management of this condition.

Potassium Iodide Yamazen Seiyaku description

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Saturated solution of Potassium Iodide Yamazen Seiyaku is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). Potassium Iodide Yamazen Seiyaku can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.

Potassium Iodide Yamazen Seiyaku dosage

Potassium Iodide Yamazen Seiyaku Dosage

Applies to the following strength(s): 1 g/mL; 325 mg/5 mL; 130 mg; 65 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cough

300 to 650 mg orally 3 to 4 times a day.

Usual Adult Dose for Hyperthyroidism

Oral solution: 250 mg orally 3 times a day. Give for 10 to 14 days prior to thyroid surgery.

May be given as 0.25 mL of a 1 g/mL potassium iodine solution (Potassium Iodide Yamazen Seiyaku) or as 4 mL of 325 mg/5 mL solution. Alternatively, 2 to 6 drops of a 10% Potassium Iodide Yamazen Seiyaku/5% iodine solution may be given orally 3 times a day with food.

Usual Adult Dose for Cutaneous Sporotrichosis

250 to 500 mg orally 3 times a day. Increase gradually to a maximum of 2 to 2.5 grams 3 times a day. Continue at maximum tolerated dose until the cutaneous lesions have resolved, usually 6 to 12 weeks.

Usual Adult Dose for Radiation Emergency

Pregnant or lactating women with exposure >= 5 centigrays (cGy): 130 mg orally per day.

>18 and <=40 years with exposure >= 10 centigrays (cGy): 130 mg orally per day.

>40 years with exposure >= 500 centigrays (cGy): 130 mg orally per day.

Usual Pediatric Dose for Cough

60 to 250 mg orally every 4 to 6 times a day. Maximum single dose 500 mg.

Usual Pediatric Dose for Hyperthyroidism

Oral solution: 250 mg orally 3 times a day. Give for 10 to 14 days prior to thyroid surgery.

Usual Pediatric Dose for Cutaneous Sporotrichosis

250 to 500 mg orally 3 times a day. Increase gradually to a maximum of 1.25 to 2 grams 3 times a day. Continue at maximum tolerated dose until the cutaneous lesions have resolved, usually 6 to 12 weeks.

Usual Pediatric Dose for Radiation Emergency

<=1 month with exposure >= 5 centigrays (cGy): 16 mg orally per day.

>1 month <=3 years with exposure >= 5 centigrays (cGy): 32 mg orally per day.

>3 years <= 18 years (less than 70 kg) with exposure >= 5 centigrays (cGy): 65 mg orally per day.

>13 years >= 70 kg with exposure >= 5 centigrays (cGy): 130 mg orally per day.

Renal Dose Adjustments

Potassium Iodide Yamazen Seiyaku should be used cautiously in patients with renal dysfunction. Due to impaired renal filtering of electrolytes, an increase in serum potassium can occur in patients with renal impairment.

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Other Comments

Administer after meals with food or milk or dilute with a large quantity of water, fruit juice, or broth.

More about Potassium Iodide Yamazen Seiyaku

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Potassium Iodide Yamazen Seiyaku interactions

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What other drugs will affect Potassium Iodide Yamazen Seiyaku?

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Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: ACE inhibitors (e.g., captopril, lisinopril), angiotensin receptor blockers (ARBs such as losartan, valsartan), certain "water pills" (potassium-sparing diuretics such as amiloride, spironolactone, triamterene), drospirenone, eplerenone, lithium, potassium-containing drugs (e.g., supplements such as potassium chloride).

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Potassium Iodide Yamazen Seiyaku side effects

See also:
What are the possible side effects of Potassium Iodide Yamazen Seiyaku?

Applies to Potassium Iodide Yamazen Seiyaku: oral solution, oral syrup

As well as its needed effects, Potassium Iodide Yamazen Seiyaku (the active ingredient contained in Potassium Iodide Yamazen Seiyaku) may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Potassium Iodide Yamazen Seiyaku, check with your doctor or nurse as soon as possible:

Less common:

With long-term use

Minor Side Effects

Some Potassium Iodide Yamazen Seiyaku side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common:

Potassium Iodide Yamazen Seiyaku contraindications

See also:
What is the most important information I should know about Potassium Iodide Yamazen Seiyaku?

Hypersensitivity to iodide, iodine, or any component of the formulation; dermatitis herpetiformis; hypocomplementemic vasculitis, nodular thyroid condition with heart disease

Active ingredient matches for Potassium Iodide Yamazen Seiyaku:

Potassium Iodide in Japan.


List of Potassium Iodide Yamazen Seiyaku substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Tablet; Oral; Potassium Iodide 65 mg
10ml$ 0.37
Sski solution 1 g/mL (Upsher-smith)
Tablet; Oral; Potassium Iodide 0.09 mg
Tablet; Oral; Potassium Iodide 130 mg (Carter horner)
Tablet; Oral; Potassium Iodide 130 mg
Tablet; Oral; Potassium Iodide 65 mg
Thyrosafe tablet 65 mg (Recip Ab (Canada))
Thyrosafe tablet 65 mg/1 (Recipharm Ab (Publ, US))
Tincture Iodine Skin 50 ml Solution (Agrawal Pharmaceuticals)$ 0.58
Tincture Iodine Skin 400 ml Solution (Agrawal Pharmaceuticals)$ 2.17
Tincture Iodine Skin 100 ml Solution (Agrawal Pharmaceuticals)$ 0.84
Tincture Iodine Skin 15 ml Solution (Agrawal Pharmaceuticals)$ 0.22
Tonex P 50+100+50 Tablet (Western Remedies (India))$ 0.03

References

  1. DailyMed. "POTASSIUM IODIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "Potassium". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. PubChem. "potassium iodide". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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