Precaine B Uses

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What is Precaine B?

Precaine B is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.

Precaine B is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, teething pain, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on a surface of the body. Precaine B is also used to numb the skin or surfaces inside the mouth, nose, throat, vagina, or rectum to lessen the pain of inserting a medical instrument such as a tube or speculum.

There are many brands and forms of Precaine B available and not all brands are listed on this leaflet.

Precaine B may also be used for purposes not listed in this medication guide.

Precaine B indications

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Precaine B is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.

Precaine B is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, teething pain, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on a surface of the body. Precaine B is also used to numb the skin or surfaces inside the mouth, nose, throat, vagina, or rectum to lessen the pain of inserting a medical instrument such as a tube or speculum.

Precaine B may also be used for other purposes not listed in this medication guide.

How should I use Precaine B?

Use Precaine B as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Precaine B.

Uses of Precaine B in details

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Precaine B is topically used for the treatment of itching and irritation caused by conditions like insect bites, nettle stings, cuts and scrapes, skin chafe and external vaginal and anal itching. It is also used for treating pain and itching due to certain ear infections and in the treatment of mouth ulcers and toothache.

Precaine B description

A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. [PubChem]

Precaine B dosage

Usual Adult Dose for Anesthesia:

Precaine B 20% mucous membrane spray:

Awake intubation, oral airway, bronchoscopy: Apply 1/2 second burst to buccal folds. Instruct patient to swallow several times. Wait 1 minute, then begin procedure.

Upper endoscopy: Apply 1/2 second burst to each buccal fold and instruct patient to swallow several times. Wait 30 seconds, then insert scope.

Esophageal motility: Apply no longer than 1/2 second burst to each naris. Wait 30 to 60 seconds, then insert transducer.

Indirect laryngoscopy, head and neck examinations: Spray 1/2 second burst to each buccal fold, instruct patient to swallow several times. Wait 30 to 60 seconds before initiating procedure.

Arch bar removal: Spray affected area for no longer than 1/2 second. Wait 30 to 60 seconds, then remove arch bar.

Stomatitis, mucositis, pharyngitis, thrush, cancer of throat: Apply topically to affected area(s) as needed.

Precaine B 20% mucous membrane gel:

Awake intubation, oral airway, bronchoscopy: Apply a small amount to naris prior to nasal intubation.

Proctoscopy, flexible sigmoidoscopy: Apply topically to rectal area, wait 30 to 60 seconds then initiate procedure.

Stomatitis, mucositis, pharyngitis, thrush, cancer of throat: Apply topically to affected area(s) as needed.

Precaine B 20% mucous membrane liquid:

Esophageal motility: Tilt the patient's head back and drip 2 to 3 drops into the naris prior to inserting the transducer.

Indirect laryngoscopy, head and neck examinations: Gargle 1 teaspoonful for approximately 15 seconds, then spit remaining out. Wait 30 to 60 seconds, then initiate procedure.

Nasal biopsies: Tilt patient's head back and drip 2 to 3 drops into each naris. Wait 30 to 60 seconds, then initiate procedure.

Stomatitis, mucositis, pharyngitis, thrush, cancer of throat: Apply topically to affected area(s) as needed.

Precaine B 20% mucous membrane swab:

Nasal biopsies: Apply topically to naris. Wait 30 to 60 seconds, then initiate procedure.

Precaine B 10% to 15% mucous membrane gel: Apply topically to affected area(s) of mouth and gums up to 4 times daily.

Precaine B 10% mucous membrane powder for reconstitution:

Oral mucositis aphthous ulcers, cancer sores, stomatitis, oral lesions and tissue injury caused by ill fitting dentures and gum disease, and oral problems associated with HIV: Apply topically to affected area(s) of mouth and gums every 4 to 6 hours, not to exceed four doses daily.

Precaine B oral lozenge:

Sore throat pain, mouth pain: 1 lozenge dissolved in mouth every 2 hours as needed.

Usual Adult Dose for Hemorrhoids:

Precaine B 20% rectal ointment: After cleansing area with soap and water, apply externally to affected area(s) as needed up to 6 times a day.

Usual Adult Dose for Pain:

Precaine B 20% gel:

Sunburn: Apply to affected area as needed up to 4 times a day.

Precaine B 20% spray:

Sunburn, pain, insect bites, pruritus: Hold container approximately 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B 20% cream:

Sunburn, pain, pruritus, insect bites, poison ivy: Apply to affected area as needed not more than 1 to 3 times a day.

Precaine B ointment:

Insect bites: Apply topically to affected area(s) as needed.

Precaine B 20% liquid:

Pain: Apply to affected area(s) as needed up to 4 times a day.

Precaine B 5% spray:

Sunburn, pain, insect bites, pruritus: Hold container approximately 10 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B cream:

Pruritus, sunburn, insect bites, pain: Apply sparingly to affected area(s) as needed up to 3 or 4 times a day.

Precaine B spray:

Sunburn, pruritus: Hold container approximately 4 to 6 inches from skin and spray sparingly to affected area(s) as needed up to 3 times a day.

Precaine B sore throat lozenges:

Dissolve 1 lozenge slowly in the mouth every 2 hours as needed.

Usual Adult Dose for Pruritus:

Precaine B 20% gel:

Sunburn: Apply to affected area as needed up to 4 times a day.

Precaine B 20% spray:

Sunburn, pain, insect bites, pruritus: Hold container approximately 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B 20% cream:

Sunburn, pain, pruritus, insect bites, poison ivy: Apply to affected area as needed not more than 1 to 3 times a day.

Precaine B ointment:

Insect bites: Apply topically to affected area(s) as needed.

Precaine B 20% liquid:

Pain: Apply to affected area(s) as needed up to 4 times a day.

Precaine B 5% spray:

Sunburn, pain, insect bites, pruritus: Hold container approximately 10 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B cream:

Pruritus, sunburn, insect bites, pain: Apply sparingly to affected area(s) as needed up to 3 or 4 times a day.

Precaine B spray:

Sunburn, pruritus: Hold container approximately 4 to 6 inches from skin and spray sparingly to affected area(s) as needed up to 3 times a day.

Precaine B sore throat lozenges:

Dissolve 1 lozenge slowly in the mouth every 2 hours as needed.

Usual Adult Dose for Burns - External:

Precaine B 20% gel:

Sunburn: Apply to affected area as needed up to 4 times a day.

Precaine B 20% spray:

Sunburn, pain, insect bites, pruritus: Hold container approximately 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B 20% cream:

Sunburn, pain, pruritus, insect bites, poison ivy: Apply to affected area as needed not more than 1 to 3 times a day.

Precaine B ointment:

Insect bites: Apply topically to affected area(s) as needed.

Precaine B 20% liquid:

Pain: Apply to affected area(s) as needed up to 4 times a day.

Precaine B 5% spray:

Sunburn, pain, insect bites, pruritus: Hold container approximately 10 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B cream:

Pruritus, sunburn, insect bites, pain: Apply sparingly to affected area(s) as needed up to 3 or 4 times a day.

Precaine B spray:

Sunburn, pruritus: Hold container approximately 4 to 6 inches from skin and spray sparingly to affected area(s) as needed up to 3 times a day.

Precaine B sore throat lozenges:

Dissolve 1 lozenge slowly in the mouth every 2 hours as needed.

Usual Pediatric Dose for Anesthesia:

Greater than or equal to 2 years to 18 years:

Precaine B 10% mucous membrane gel:

Toothache, sore gums, canker sores: Apply topically to affected area(s) up to 4 times daily. A cotton swab may be helpful when applying to young children.

Greater than or equal to 5 years to 18 years:

Precaine B oral lozenge:

Sore throat pain, mouth pain: 1 lozenge dissolved in mouth every 2 hours as needed.

Usual Pediatric Dose for Hemorrhoids:

Greater than or equal to 2 years to 18 years:

Precaine B 20% rectal ointment: Apply externally to affected area up to 6 times a day.

Usual Pediatric Dose for Pain:

Greater than or equal to 2 years to 18 years:

Precaine B

Topical 20% Gel:

Sunburn: Apply to affected area as needed up to 4 times a day.

Precaine B

Topical 20% Spray:

Sunburn, pain, insect bites, pruritus: Hold container 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B 20% cream:

Sunburn, pain, pruritus, insect bites, poison ivy: Apply to affected area as needed not more than 1 to 3 times a day.

Precaine B

Topical 20% Liquid:

Pain: Apply to affected area(s) as needed up to 4 times a day.

Precaine B

Topical 5%

Topical Spray:

Sunburn, pain, pruritus, insect bites, minor abrasions: Hold container 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B

Topical -

Topical Cream:

Pruritus, sunburn, insect bites, pain: Apply sparingly to affected area(s) as needed up to 3 or 4 times a day.

Precaine B - topical spray:

Sunburn, pruritus: Hold 4 to 6 inches from skin and spray sparingly to affected area(s) as needed up to 3 times a day.

Precaine B sore throat lozenges:

Children 5 years and older:

Dissolve 1 lozenge slowly in the mouth every 2 hours as needed.

Usual Pediatric Dose for Pruritus:

Greater than or equal to 2 years to 18 years:

Precaine B

Topical 20% Gel:

Sunburn: Apply to affected area as needed up to 4 times a day.

Precaine B

Topical 20% Spray:

Sunburn, pain, insect bites, pruritus: Hold container 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B 20% cream:

Sunburn, pain, pruritus, insect bites, poison ivy: Apply to affected area as needed not more than 1 to 3 times a day.

Precaine B

Topical 20% Liquid:

Pain: Apply to affected area(s) as needed up to 4 times a day.

Precaine B

Topical 5%

Topical Spray:

Sunburn, pain, pruritus, insect bites, minor abrasions: Hold container 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B

Topical -

Topical Cream:

Pruritus, sunburn, insect bites, pain: Apply sparingly to affected area(s) as needed up to 3 or 4 times a day.

Precaine B - topical spray:

Sunburn, pruritus: Hold 4 to 6 inches from skin and spray sparingly to affected area(s) as needed up to 3 times a day.

Precaine B sore throat lozenges:

Children 5 years and older:

Dissolve 1 lozenge slowly in the mouth every 2 hours as needed.

Usual Pediatric Dose for Burns - External:

Greater than or equal to 2 years to 18 years:

Precaine B

Topical 20% Gel:

Sunburn: Apply to affected area as needed up to 4 times a day.

Precaine B

Topical 20% Spray:

Sunburn, pain, insect bites, pruritus: Hold container 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B 20% cream:

Sunburn, pain, pruritus, insect bites, poison ivy: Apply to affected area as needed not more than 1 to 3 times a day.

Precaine B

Topical 20% Liquid:

Pain: Apply to affected area(s) as needed up to 4 times a day.

Precaine B

Topical 5%

Topical Spray:

Sunburn, pain, pruritus, insect bites, minor abrasions: Hold container 6 to 12 inches from skin and spray on affected area(s) until wet as needed up to 4 times a day. When applying to facial area spray into palm of hand, then rub on face avoiding area around eyes.

Precaine B

Topical -

Topical Cream:

Pruritus, sunburn, insect bites, pain: Apply sparingly to affected area(s) as needed up to 3 or 4 times a day.

Precaine B - topical spray:

Sunburn, pruritus: Hold 4 to 6 inches from skin and spray sparingly to affected area(s) as needed up to 3 times a day.

Precaine B sore throat lozenges:

Children 5 years and older:

Dissolve 1 lozenge slowly in the mouth every 2 hours as needed.

Precaine B interactions

See also:
What other drugs will affect Precaine B?

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Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Precaine B side effects

See also:
What are the possible side effects of Precaine B?

Applies to Precaine B: cream, film, gel/jelly, lotion, lozenge/troche, ointment, paste, powder for suspension, solution, spray, swab, tablet disintegrating

Other dosage forms:

Along with its needed effects, Precaine B (the active ingredient contained in Precaine B) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking Precaine B:

Incidence Not Known

Precaine B contraindications

See also:
What is the most important information I should know about Precaine B?

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If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Precaine B:

asthma, bronchitis, emphysema, or other breathing disorder;

heart disease;

a personal or family history of methemoglobinemia, or any genetic enzyme deficiency; or

if you smoke.

Active ingredient matches for Precaine B:

Benzocaine topical


Unit description / dosage (Manufacturer)Price, USD
Precaine B gel 221 mg/g (Pascal Company, Inc. (US))

List of Precaine B substitutes (brand and generic names):

Gel; Topical; Benzocaine 20%
Orajel Denture gel 20 % (Del Pharmaceutics (Canada) Inc.)
Gel; Buccal; Benzocaine 15%; Menthol 2%
Gel; Oral; Benzocaine 15%; Menthol 1.6%
Gel; Topical; Benzocaine 15%; Menthol 1.6%
Oral Pain Relief gel 200 mg/g (Discount Drug Mart, Inc. (US))
Gel; Topical; Benzocaine 7.5%
Cream; Topical; Benzyl Alcohol 1.5%; Chloroxylenol 1.5%; Eucalyptus Oil 1%; Zinc Oxide 2%
Gel; Dental; Benzocaine 20% (Protec (Cipla Ltd))
TOPEX Capsule/ Tablet / 25mg / 10 units (Protec (Cipla Ltd))$ 0.47
TOPEX Capsule/ Tablet / 100mg / 10 units (Protec (Cipla Ltd))$ 1.57
Topex 25mg TAB / 10 (Protec (Cipla Ltd))$ 0.47
Topex 100mg TAB / 10 (Protec (Cipla Ltd))$ 1.57
25 mg x 10's (Protec (Cipla Ltd))$ 0.47
100 mg x 10's (Protec (Cipla Ltd))$ 1.57
Topex 100 mg Tablet (Protec (Cipla Ltd))$ 0.16
Topex 25 mg Tablet (Protec (Cipla Ltd))$ 0.05
TOPEX tab 25 mg x 10's (Protec (Cipla Ltd))$ 0.47
TOPEX tab 100 mg x 10's (Protec (Cipla Ltd))$ 1.57
Topex 100mg Tablet (Protec (Cipla Ltd))$ 0.17
Topex Expectorant (Protec (Cipla Ltd))$ 0.01
Topex Syrup (Protec (Cipla Ltd))$ 0.30

References

  1. PubChem. "benzocaine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "benzocaine". http://www.drugbank.ca/drugs/DB01086 (accessed September 17, 2018).
  3. DTP/NCI. "benzocaine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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