• Pyrantel Embonate indications
• Pyrantel Embonate dosage
• Pyrantel Embonate interactions
• Pyrantel Embonate side effects
• Pyrantel Embonate contraindications

What is Pyrantel Embonate?

Pyrantel Embonate belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.

Pyrantel Embonate is used to treat pinworms (enterobiasis; oxyuriasis).

Pyrantel Embonate may also be used for other worm infections as determined by your doctor.

Pyrantel Embonate works by paralyzing the worms. They are then passed in the stool.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Pyrantel Embonate is used in certain patients with the following medical condition:

• Common roundworm infection
• Hookworm infection
• More than one worm infection at a time

For patients taking Pyrantel Embonate for hookworm infection :

• Anemia (iron-poor blood) may occur in patients with hookworm infections. Therefore, your doctor may want you to take iron supplements to help clear up the anemia. If so, it is important to take iron every day while you are being treated for hookworms. Do not miss any doses. Your doctor may also want you to keep taking iron supplements for up to 6 months after you stop taking Pyrantel Embonate. If you have any questions about this, check with your doctor.

Pyrantel Embonate indications

worm infections

How should I use Pyrantel Embonate?

Use Pyrantel Embonate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Pyrantel Embonate may be taken on an empty stomach or with food, milk, or juice.
• Shake well before using a dose of Pyrantel Embonate.
• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
• Wear tight underwear both day and night while taking Pyrantel Embonate.
• Pyrantel Embonate is usually prescribed as a single dose.
• Only one dose of Pyrantel Embonate is required. If you forget to take Pyrantel Embonate, take it as soon as you remember.

Ask your health care provider any questions you may have about how to use Pyrantel Embonate.

Pyrantel Embonate dosage

Pyrantel Embonate Dosage

Applies to the following strength(s): 144 mg/mL; 180 mg; 50 mg/mL

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

• Enterobiasis
• Pinworm Infection (Enterobius vermicularis)
• Hookworm Infection (Necator or Ancylostoma)
• Ascariasis
• Trichostrongylosis
• Moniliformis Infection

Usual Pediatric Dose for:

• Enterobiasis
• Pinworm Infection (Enterobius vermicularis)
• Hookworm Infection (Necator or Ancylostoma)
• Ascariasis
• Trichostrongylosis
• Moniliformis Infection

Additional dosage information:

• Renal Dose Adjustments
• Liver Dose Adjustments
• Dose Adjustments
• Precautions
• Dialysis
• Other Comments

Usual Adult Dose for Enterobiasis

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Pinworm Infection (Enterobius vermicularis)

11 mg/kg base (maximum 1 g) orally once. Repeat dose in 2 weeks.

Usual Adult Dose for Hookworm Infection (Necator or Ancylostoma)

11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Adult Dose for Ascariasis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Trichostrongylosis

11 mg/kg base (maximum 1 g) orally once.

Usual Adult Dose for Moniliformis Infection

11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Usual Pediatric Dose for Enterobiasis

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Pinworm Infection (Enterobius vermicularis)

>=2 years: 11 mg/kg base (maximum 1 g) once. Repeat dose in 2 weeks.

Usual Pediatric Dose for Hookworm Infection (Necator or Ancylostoma)

>=2 years: 11 mg/kg base (maximum 1 g) orally daily for 3 days.

Usual Pediatric Dose for Ascariasis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Trichostrongylosis

>=2 years: 11 mg/kg base (maximum 1 g) orally once.

Usual Pediatric Dose for Moniliformis Infection

>=2 years: 11 mg/kg base (maximum 1 g) orally once. Repeat dose twice at 2 weeks intervals.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Pyrantel Embonate is contraindicated in patients with hepatic disease.

Dose Adjustments

In the treatment of ascariasis, Pyrantel Embonate may be used only if it has been determined that the worm load will not worsen obstruction.

Precautions

Pyrantel Embonate is contraindicated in patients with hepatic disease.

When one individual in a household has pinworms, the entire household should be treated unless otherwise advised. Pinworm infections are easily transmitted to others in the same household.

Pyrantel Embonate should be used with caution in patients with severe malnutrition or anemia. Supportive therapy is recommended for anemic, dehydrated, or malnourished patients prior to administration of the drug.

Other medications are known to antagonize the anthelmintic effect of Pyrantel Embonate. Patients should be advised to consult with their physician before initiating any drug therapy while receiving Pyrantel Embonate.

Dialysis

Data not available

Other Comments

The dose should be taken as a single oral dose. It may be taken alone or with milk or fruit juice.

Pyrantel Embonate pamoate 2.9 g is approximately equivalent to 1 g of Pyrantel Embonate (base).

More about Pyrantel Embonate

• Side Effects
• During Pregnancy or Breastfeeding
• Dosage Information
• Drug Interactions
• Support Group
• En Espanol
• 4 Reviews - Add your own review/rating

Consumer resources

• Pyrantel Embonate chewable tablets
• Pyrantel Embonate pamoate
• Pyrantel Embonate pamoate suspension
• Pyrantel Embonate
• Pyrantel Embonate (Advanced Reading)

• Other brands: Pin-X, Pinworm Medicine, Reese's Pinworm Medicine, Pinworm Caplets, More (2) »

Professional resources

• Pyrantel Embonate Pamoate (AHFS Monograph)

Related treatment guides

• Pinworm Infection (Enterobius vermicularis)
• Hookworm Infection (Necator or Ancylostoma)
• Ascariasis
• Enterobiasis
• Moniliformis Infection
• More (1) »

Pyrantel Embonate interactions

See also:
What other drugs will affect Pyrantel Embonate?

• Dexamethasone

Steady-state trough concentrations of albendazole sulfoxide were about 56% higher when 8 mg dexamethasone was coadministered with each dose of albendazole (15 mg/kg/day) in 8 neurocysticercosis patients.

• Praziquantel

• Cimetidine

Albendazole sulfoxide concentrations in bile and cystic fluid were increased (about 2-fold) in hydatid cyst patients treated with cimetidine (10 mg/kg/day) (n = 7) compared with albendazole (20 mg/kg/day) alone (n = 12). Albendazole sulfoxide plasma concentrations were unchanged 4 hours after dosing.

• Theophylline

The pharmacokinetics of theophylline (aminophylline 5.8 mg/kg infused over 20 minutes) were unchanged following a single oral dose of albendazole (400 mg) in 6 healthy subjects.

Pyrantel Embonate side effects

See also:
What are the possible side effects of Pyrantel Embonate?

Applies to Pyrantel Embonate: oral suspension, oral tablet, oral tablet chewable

As well as its needed effects, Pyrantel Embonate may cause unwanted side effects that require medical attention.

Severity: Moderate

If any of the following side effects occur while taking Pyrantel Embonate, check with your doctor or nurse as soon as possible:

Rare

• Skin rash

Minor Side Effects

Some Pyrantel Embonate side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common:

• Abdominal or stomach cramps or pain
• diarrhea
• dizziness
• drowsiness
• headache
• irritability
• loss of appetite
• nausea or vomiting
• trouble in sleeping

Pyrantel Embonate contraindications

See also:
What is the most important information I should know about Pyrantel Embonate?

This medicine is contraindicated in patients with known hypersensitivity to the benzimidazole class of compounds or any components of this medicine.

Active ingredient matches for Pyrantel Embonate:

Pyrantel Embonate

References

1. PubChem. "PYRANTEL". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
2. DrugBank. "Pyrantel". http://www.drugbank.ca/drugs/DB11156 (accessed September 17, 2018).
3. MeSH. "Antinematodal Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

User reports

Consumer reviews

Information checked by Dr. Sachin Kumar, MD Pharmacology