Pregnancy of Rexidin PLUS in details
Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).
Rexidin PLUS breastfeeding
One infant experienced episodes of bradycardia and cyanotic spells which may have been due to the application of chlorhexidine directly onto the mother's breast during breast-feeding. Chlorhexidine was detected in the blood of the infant.
There are no data on the excretion of chlorhexidine into human milk when given as an oral rinse. Some studies have reported that any chlorhexidine ingested is poorly absorbed; therefore, excretion into breast milk is unlikely. The manufacturer recommends that caution be used when administering chlorhexidine to nursing women.
References
- DailyMed. "CHLORHEXIDINE GLUCONATE; ISOPROPYL ALCOHOL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubMed Health. "Hibiclens: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
- Human Metabolome Database (HMDB). "Chlorhexidine: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).
Reviews
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
