Rhabarex B Uses

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What is Rhabarex B?

Rhabarex B (Rhabarex B) is a laxative that stimulates bowel movements.

Rhabarex B is used to treat constipation or to empty the bowels before surgery, colonoscopy, x-rays, or other intestinal medical procedure.

Rhabarex B tablets generally produce a bowel movement in 6 to 12 hours. Rhabarex B suppositories generally produces bowel movements in 15 minutes to 1 hour.

Rhabarex B indications

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Rhabarex B is a laxative that stimulates bowel movements.

Rhabarex B is used to treat constipation or to empty the bowels before surgery, colonoscopy, x-rays, or other intestinal medical procedure.

How should I use Rhabarex B?

Use Rhabarex B enema as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Rhabarex B enema.

Uses of Rhabarex B in details

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Rhabarex B is used to treat constipation. It may also be used to clean out the intestines before a bowel examination/surgery. Rhabarex B is known as a stimulant laxative. It works by increasing the movement of the intestines, helping the stool to come out.

How to use Rhabarex B

Take this medication by mouth as directed by your doctor. If you are self-treating, follow all directions on the product package. If you are uncertain about any of the information, ask your doctor or pharmacist.

Swallow this medication whole. Do not crush, chew, or break the tablet or take it within 1 hour of antacids, milk, or milk products. Doing so can destroy the coating on the tablet and may increase the risk of stomach upset and nausea.

Dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this drug more often than directed. Do not take this medication for more than 7 days unless directed by your doctor. Serious side effects may occur with overuse of this medication.

It may take 6 to 12 hours before this medication causes a bowel movement. Tell your doctor if your condition persists or worsens, or if bleeding from the rectum occurs. If you think you may have a serious medical problem, seek immediate medical attention.

Rhabarex B description

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Rhabarex B may also contain the following excipients: Tablet: Lactose monohydrate, dried and undried maize starch, glycerol, magnesium stearate, crystallized sugar, talc, acacia, titanium dioxide, methacrylic acid-methyl methacrylate copolymer (1:1) and (1:2), PEG 6000, ferric oxide yellow (E172), beeswax white, carnauba wax, dibutyl phthalate, p-hydroxybenzoic acid methyl ester, p-hydroxybenzoic acid propyl ester. Suppositories: Hard fat Witepsol W45, E76.

Rhabarex B is 4,4'-diacetoxy-diphenyl-(pyridyl-2)-methane.

Rhabarex B dosage

Rhabarex B Dosage

Applies to the following strength(s): 5 mg; 10 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Bowel Preparation

5 to 15 mg (1 to 3 tablets) orally once a day as needed or

10 mg (1 suppository) rectally once a day as needed or

10 mg rectal liquid once a day as needed.

Usual Adult Dose for Constipation

5 to 15 mg (1 to 3 tablets) orally once a day as needed or

10 mg (1 suppository) rectally once a day as needed or

10 mg rectal liquid once a day as needed.

Renal Dose Adjustments

No adjustment recommended.

Caution is recommended when using Rhabarex B enemas containing monobasic or dibasic sodium phosphate in patients with impaired renal function or where colostomy exists as hypocalcemia, hyperphosphatemia, hypernatremia, and acidosis may occur.

Liver Dose Adjustments

No adjustment recommended

Dialysis

No adjustment recommended

Other Comments

Alleviation of constipation can be expected within 8 to 12 hours if taken at bedtime or within 6 hours if taken during waking hours.

More about Rhabarex B

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Rhabarex B interactions

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What other drugs will affect Rhabarex B?

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Antacids: May diminish the therapeutic effect of Rhabarex B. Antacids may cause the delayed-release Rhabarex B tablets to release drug prior to reaching the large intestine. Gastric irritation and/or cramps may occur. Management: Antacids should not be used within 1 hour before Rhabarex B administration. Consider therapy modification

Dichlorphenamide: Laxatives may enhance the hypokalemic effect of Dichlorphenamide. Monitor therapy

Polyethylene Glycol-Electrolyte Solution: Rhabarex B may enhance the adverse/toxic effect of Polyethylene Glycol-Electrolyte Solution. Monitor therapy

Rhabarex B side effects

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What are the possible side effects of Rhabarex B?

Applies to Rhabarex B: oral tablets delayed-release, rectal suppositories, rectal suspension

Side effects include:

Some degree of abdominal discomfort, nausea, cramps, griping, and/or faintness with therapeutic doses.

Diarrhea, GI irritation, and fluid and electrolyte depletion.

Gastric irritation and the possibility of vomiting if enteric coating of tablets is disrupted.

Rectal administration of Rhabarex B (the active ingredient contained in Rhabarex B Uniserts) suspensions or suppositories may cause irritation and a sensation of burning of the rectal mucosa and mild proctitis.

Hepatotoxicity if sufficient tannic acid is absorbed from Rhabarex B tannex.

Rhabarex B contraindications

See also:
What is the most important information I should know about Rhabarex B?

Hypersensitivity to any component.

- Colopathies organic inflammatory (ulcerative colitis, Crohn’s disease...).

- Subocclusif occlusive syndrome.

- Abdominal pain syndromes of unknown cause.

- States of severe dehydration with electrolyte depletion.

RECOMMENDED:

- Pregnancy: there is no reliable data on teratogenesis in animals. Clinically, there is currently no adequate data to evaluate a possible effect of malformation or Rhabarex B fetotoxic when administered during pregnancy. Consequently, the use of Rhabarex B is not recommended during pregnancy. This item does not recommend a systematic argument for abortion, but leads to an attitude of caution and a prenatal care oriented.

- Breast-feeding: Because it passes through breast milk, the use of Rhabarex B is discouraged.

- Concomitant use not recommended: medication torsade de pointes (amiodarone, astemizole, bepridil, bretylium, disopyramide, erythromycin IV, halofantrine, pentamidine, quinidine, sparfloxacin, sotalol, sultopride, terfenadine, vincamine).



Active ingredient matches for Rhabarex B:

Bisacodyl in Germany.


List of Rhabarex B substitutes (brand and generic names)

Sort by popularity
Unit description / dosage (Manufacturer)Price, USD
S.L. Laxative 5 mg x 1's
Saflax 5mg TAB / 100 (Psyco Remedies.)$ 0.96
5 mg x 100's (Psyco Remedies.)$ 0.96
Saflax 5 mg Tablet (Psyco Remedies.)$ 0.01
SAFLAX tab 5 mg x 10's (Psyco Remedies.)$ 0.10
Suppositories; Rectal; Bisacodyl 10 mg
Suppositories; Rectal; Bisacodyl 10 mg (Pharmascience)
Tablet; Oral; Bisacodyl 5 mg (Pharmascience)
Dragee; Oral; Bisacodyl 5 mg
Dragee, Gastro-Resistant; Oral; Bisacodyl (Stada)
Stolax 10 mg x 6's (Sanbe)$ 3.89
Suben 5 mg x 20's
Sunny Laxative 5 mg x 1's
5 mg x 10's (Ind-Swift Limited)$ 0.12
Swilax 5mg TAB / 10 (Ind-Swift Limited)$ 0.12
Swilax 5 mg Tablet (Ind-Swift Limited)$ 0.01
SWILAX 5 MG TABLET 1 strip / 10 tablets each (Ind-Swift Limited)$ 0.06
SWILAX tab 5 mg x 10's (Ind-Swift Limited)$ 0.12
Swilax 5mg TAB / 10 (Ind-Swift Limited)$ 0.12
Swilax 5mg Tablet (Ind-Swift Limited)$ 0.01
Dragee; Oral; Aloe; Belladonna; Bisacodyl 5 mg; Cascara; Docusate Sodium; Matricaria; Senna (Singer)
Dragee; Oral; Bisacodyl 5 mg (Vifor)
Suppositories; Rectal; Bisacodyl
Dragee, Enteric Coated; Oral; Bisacodyl (Hommel)
Dragee, Enteric Coated; Oral; Bisacodyl
Suppositories; Rectal; Bisacodyl 10 mg
The Magic Bullet suppository 10 mg/1 (Concepts In Confidence (US))
The Magic Bullet suppository 10 mg (D & C Mobility Solutions Inc. (Canada))

References

  1. DailyMed. "BISACODYL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "bisacodyl". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "Bisacodyl". http://www.drugbank.ca/drugs/DB09020 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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