Salbrox AP Actions

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Actions of Salbrox AP in details

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Description: Salbrox AP is an indirect acting sympathomimetic, often used orally as the HCl salt for nasal congestion. It has been withdrawn in several countries due to increased risk of haemorrhagic strokes.

Pharmacokinetics:

Absorption: Readily and completely absorbed from GI tract. Time to peak plasma concentration: 1-2 hr.

Metabolism: Undergoes partial hepatic metabolism.

Excretion: Via urine 80-90% (unchanged). Half-life: Approx 3-5 hr.

How should I take Salbrox AP?

Take Salbrox AP exactly as directed by your doctor, or follow the instructions that accompany the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Never take this medication in larger doses or more often than is recommended. Too much Salbrox AP could be very harmful.

If your symptoms are accompanied by a high fever, or if they do not improve in 7 days, see your doctor.

Store Salbrox AP at room temperature away from moisture and heat.

Salbrox AP pharmacology

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Salbrox AP (PPA), a sympathomimetic agent structurally similar to pseudoephedrine, is used to treat nasal congestion. Salbrox AP is found in appetite suppressant formulations and with guaifenesinin in cough-cold formulations. In 2000, the FDA requested that all drug companies discontinue marketing products containing Salbrox AP, due to an increased risk of hemorrhagic stroke in women who used Salbrox AP.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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