Septivon 1.5% Uses

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What is Septivon 1.5%?

Septivon 1.5% is used to help treat periodontal disease (a disease of your gums), which is caused by bacteria growing beneath the gum line. Septivon 1.5% works by killing the bacteria. Up to eight Septivon 1.5% implants are placed between your teeth and gums in places where the gum has a deep pocket. Your dentist will place the Septivon 1.5% implants after your teeth have been thoroughly cleaned.

Septivon 1.5% is available only with your dentist's prescription.

Septivon 1.5% indications

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For local use of Septivon 1.5% ICPA Health Products: trichomonas coleitis, cervical erosion, itching of the vulva, prevention of sexually transmitted diseases (including gonorrhea, syphilis, trichomoniasis, chlamydia, ureaplasmosis); gingivitis, stomatitis, aphthae, paradont, alveolitis, disinfection of removable dentures, sore throat; postoperative care for patients in ENT and dentistry.

Treatment of wounds, burn wounds and surfaces, disinfection of the patient's skin.

Treatment of surgeons', nurses' hands and operating field before diagnostic manipulation operation.

Disinfection of work surfaces of devices (including thermometers) and equipment which heat treatment is not desirable.

How should I use Septivon 1.5%?

Use Septivon 1.5% liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Septivon 1.5% liquid.

Uses of Septivon 1.5% in details

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Garlic has been used for hardening of the arteries (atherosclerosis) and high blood pressure (hypertension). Consult your doctor for more information if you have heart disease or high blood pressure. Garlic has also been used to prevent tick bites.

Some herbal/dietary supplement products have been found to contain possibly harmful impurities/additives. Check with your pharmacist for more details about the brand you use.

The FDA has not reviewed this product for safety or effectiveness. Consult your doctor or pharmacist for more details.

How to use Septivon 1.5%

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Septivon 1.5% description

Septivon 1.5% mouthwash contains Chlorhexidine digluconate 1% v/v, equivalent to Septivon 1.5% gluconate solution 0.2% w/v. It also contains ethanol, macrogolglycerol hydroxystearate, sorbitol, flavour and water.

Septivon 1.5% dosage

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Usual Adult Dose for Gingivitis

15 mL twice daily after brushing.

Oral rinse should be retained for 30 seconds then expectorated after rinsing.

Usual Adult Dose for Mucositis

15 mL twice daily after brushing.

Oral rinse should be retained for 30 seconds then expectorated after rinsing.

Usual Adult Dose for Periodontitis

Initial: One 2.5 mg chip inserted into a periodontal pocket with probing pocket depth greater than or equal to 5 mm, up to 8 chips in one visit.

Maintenance: Administration is recommended once every 3 months in pockets with remaining probing depth greater than or equal to 5 mm.

Usual Adult Dose for Skin Disinfection, Preoperative

Septivon 1.5% gluconate 2% cloth:

Patient preoperative skin preparation:

Hold package in one hand and lift flap on backside of package with the other hand. Grasp flap at top and pull down to tear flap away and expose foam. Alternatively, using sterile scissors, cut off end seal of package. Transfer contents onto prep table, avoiding contact between cloths and outside of package to reduce risk of cloth contamination. Use the first cloth to prepare the skin area indicated for a moist or dry site, making certain to keep the second cloth where it will not be contaminated. Use the second cloth to prepare larger areas.

DRY SURGICAL SITES: (such as the abdomen or arm): Use one cloth to cleanse each 161 cm2 area (approximately 5 x 5 inches) of skin to be prepared. Vigorously scrub skin back and forth for 3 minutes, completely wetting treatment area, then discard. Allow area to air dry for one minute. Do not rinse.

MOIST SURGICAL SITES: (such as the inguinal fold): Use one cloth to cleanse each 65 cm2 area (approximately 2 x 5 inches) of skin to be prepared. Vigorously scrub skin back and forth for 3 minutes, completely wetting treatment area, then discard. Do not rinse.

Septivon 1.5% gluconate 4% solution:

SURGICAL HAND SCRUB: Do not dilute. Wet hands and forearms with water and scrub for 3 minutes with about 5 ml and a wet brush, paying close attention to the nails, cuticles, and interdigital spaces. Wash for an additional 3 minutes with 5 ml and rinse under running water. Dry thoroughly.

HEALTHCARE PERSONNEL HANDWASH: Do not dilute. Wet hands with water. Dispense about 5 ml into cupped hands and wash in a vigorous manner for 15 seconds. Rinse and dry thoroughly.

PATIENT PREOPERATIVE SKIN PREPARATION: Do not dilute. Apply liberally to surgical site and swab for at least 2 minutes. Dry with a sterile towel. Repeat procedure for an additional 2 minutes and dry with a sterile towel.

SKIN WOUND AND GENERAL SKIN CLEANSING: Do not dilute. Thoroughly rinse the area to be cleaned with water. Apply a minimum amount necessary to cover the skin or would area and wash gently. Rinse again thoroughly.

Usual Pediatric Dose for Gingivitis

The safety and efficacy of Septivon 1.5% gluconate has not been established in patients less than 18 years old. However, the use of Septivon 1.5% gluconate may be appropriate in some situations.

15 mL twice daily after brushing.

Oral rinse should be retained for 30 seconds then expectorated after rinsing.

Usual Pediatric Dose for Mucositis

The safety and efficacy of Septivon 1.5% gluconate has not been established in patients less than 18 years old. However, the use of Septivon 1.5% gluconate may be appropriate in some situations.

15 mL twice daily after brushing.

Oral rinse should be retained for 30 seconds then expectorated after rinsing.

Usual Pediatric Dose for Periodontitis

The safety and efficacy of Septivon 1.5% gluconate has not been established in patients less than 18 years old. However, the use of Septivon 1.5% gluconate may be appropriate in some situations.

Initial: One 2.5 mg chip inserted into a periodontal pocket with probing pocket depth greater than or equal to 5 mm, up to 8 chips in one visit.

Maintenance: Administration is recommended once every 3 months in pockets with remaining probing depth greater than or equal to 5 mm.

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Dialysis

No adjustment recommended

Other Comments

Septivon 1.5% topical cloths are not sterile.

Septivon 1.5% topical cloths should not be microwaved.

Septivon 1.5% solution should be used with care in premature infants or infants under 2 months of age. These products may cause irritation or chemical burns.

Septivon 1.5% topical cloths should not be used in premature or low birthweight infants, infants receiving phototherapy, or infants less than 2 months of age. Septivon 1.5% topical cloths and Septivon 1.5% 4% solution should not be used for lumbar punctures or in contact with the meninges, or on open wounds or as a general skin cleanser.

Septivon 1.5% topical cloths and Septivon 1.5% 4% solution should not make contact with the eyes, nose, or mouth. If contact occurs, the affected area should be washed with cold water and a doctor should be contacted.

Septivon 1.5% 4% solution should not be diluted.

Repeated general cleansing of large areas of the body with Septivon 1.5% 4% topical solution should be avoided except when the underlying condition makes it necessary to reduce the bacterial population of the skin.

Septivon 1.5% interactions

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Septivon 1.5% is incompatible with the soap, and detergents containing anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose).

Septivon 1.5% ICPA Health Products is compatible with any medication containing cationic group (cetrimonium bromide, benzalkonium chloride).

Septivon 1.5% side effects

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What are the possible side effects of Septivon 1.5%?

The most common side effects associated with Septivon 1.5% gluconate oral rinses are (1) an increase in staining of teeth and other oral surfaces, (2) an increase in calculus formation; and (3) an alteration in taste perception; see WARNINGS and PRECAUTIONS.

Oral irritation and local allergy-type symptoms have been spontaneously reported as side effects associated with the use of Septivon 1.5% gluconate rinse.

The following oral mucosal side effects were reported during placebo-controlled adult clinical trials: aphthous ulcer, grossly obvious gingivitis, trauma, ulceration, erythema, desquamation, coated tongue, keratinization, geographic tongue, mucocele, and short frenum. Each occurred at a frequency of less than 1.0%.

Among post marketing reports, the most frequently reported oral mucosal symptoms associated with Septivon 1.5% gluconate oral rinse are stomatitis, gingivitis, glossitis, ulcer, dry mouth, hypesthesia, glossal edema, and paresthesia.

Minor irritation and superficial desquamation of the oral mucosa have been noted in patients using Septivon 1.5% gluconate oral rinse.

There have been cases of parotid gland swelling and inflammation of the salivary glands (sialadenitis) reported in patients using Septivon 1.5% gluconate oral rinse.

Septivon 1.5% contraindications

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What is the most important information I should know about Septivon 1.5%?

Septivon 1.5% gluconate oral rinse should not be used by persons who are known to be hypersensitive to Septivon 1.5% gluconate or other formula ingredients.

Active ingredient matches for Septivon 1.5%:

Chlorhexidine in France.


List of Septivon 1.5% substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Solution; Topical; Chlorhexidine Gluconate 0.05%
Solution; Topical; Chlorhexidine Gluconate 0.05%
Solution; Topical; Alcohol 0.5%; Chlorhexidine Gluconate 70% (Acron Pharmaceuticals)
Septol 20 gm Cream (Acron Pharmaceuticals)$ 0.00
Silco Silver sulphadiazine 1 % w/w, Chlorhexidine 0.2 % w/w, Aloe15 % w/w, Allantoin 0.1 % w/w. OINT / 30g (Candor)
SILCO oint 30g (Candor)
Silron Plus Silver sulfadiazine 1 % w/w, Chlorhexidine 0.2 % w/w, Aloe15 % w/w. D-GEL / 30g (Candor (Aileron))
30mg (Candor (Aileron))
SILRON PLUS dental gel 30g (Candor (Aileron))
Silvasia-C silver Sulphadiazine 1 % w/w, Chlorhexidine 0.2 % w/w. CRM / 15g (Willow)$ 0.39
SILVASIA-C cream 15g (Willow)$ 0.39
Silvec Cream Silver sulphadiazine 1 % w/w, Chlorhexidine gluconate 0.2 %w/w. CRM / 20g (Panjon)$ 0.33
20g (Panjon)$ 0.33
SILVEC CREAM cream 20g (Panjon)$ 0.33
Silver Shield Silver sulfadiazine 1 % w/w, Chlorhexidine gluconate 1 %w/w. CRM / 25g (V.S. Healthcare Limited.)$ 0.30
25g (V.S. Healthcare Limited.)$ 0.30
Silver Shield Skin 20 gm V.S.Healthcare Cream (V.S. Healthcare Limited.)$ 0.30
Silver Shield Skin 20 gm Pharma Synth Cream (V.S. Healthcare Limited.)$ 0.40
SILVER SHIELD cream 25g (V.S. Healthcare Limited.)$ 0.30
Silverdine Silver sulfadiazine 1 % w/w, Chlorhexidine gluconate 0.2 %w/w. CRM / 20g (JK Biochem Healthcare Pvt.Ltd.)$ 0.37
Silverdine Skin 20 gm Cream (JK Biochem Healthcare Pvt.Ltd.)$ 0.37
SILVERDINE cream 20g (JK Biochem Healthcare Pvt.Ltd.)$ 0.37
Silverex-AV Silver sulphadiazine 1 % w/w, Chlorhexidine gluconate 0.2 %w/w, Aloe vera 15 % w/w. CRM / 20g (Ranbaxy (Consumer HC))$ 0.70
SILVEREX-AV cream 20g (Ranbaxy (Consumer HC))$ 0.70
Silverstar Silver sulphadiazine 1 % w/w, Chlorhexidine 0.2 % w/w. CRM / 15g (Invision Medi Sciences)$ 0.39
Silverstar Silver Sulphadiazine 1 % w/w, chlorhexidine 0.2 % w/w CRM / 15g (Invision Medi Sciences)$ 0.39
Silverstar Skin 15 gm Cream (Invision Medi Sciences)$ 0.39
SILVERSTAR cream 15g (Invision Medi Sciences)$ 0.39
Silvilak Silver sulphadiazine, Chlorhexidine gluconate. CRM / 250g (SPPL)$ 1.43
Silvilak Silver sulphadiazine , chlorhexidine gluconate. CRM / 250g (SPPL)$ 1.43
SILVILAK cream 250g (SPPL)$ 1.43
Silvo Silver sulphadiazine 1 % w/w, Chlorhexidine gluconate 0.2 %w/w. CRM / 30g (Lincoln Pharmaceuticals Ltd)$ 0.38
Silvo Silver Sulphadiazine 1% w/w, Chlorhexidine Gluconate 0.2%w/w CRM / 30g (Lincoln Pharmaceuticals Ltd)$ 0.38
Silvo Skin 30 gm Cream (Lincoln Pharmaceuticals Ltd)$ 0.38
SILVO 1%/0.2% CREAM 1 tube / 30 GM cream each (Lincoln Pharmaceuticals Ltd)$ 0.35
SILVO cream 30g (Lincoln Pharmaceuticals Ltd)$ 0.38
Silvo 1%/0.2% Cream (Lincoln Pharmaceuticals Ltd)$ 0.35
Silzen C Silver sulfadiazine 1 %, Chlorhexidine gluconate 0.2 %. CRM / 10g (Ind-Swift Limited)$ 0.27

References

  1. DailyMed. "CHLORHEXIDINE GLUCONATE; ISOPROPYL ALCOHOL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "chlorhexidine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "chlorhexidine". http://www.drugbank.ca/drugs/DB00878 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Septivon 1.5% are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Septivon 1.5%. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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