Shacold Actions

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Actions of Shacold in details

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Description: Shacold is an indirect acting sympathomimetic, often used orally as the HCl salt for nasal congestion. It has been withdrawn in several countries due to increased risk of haemorrhagic strokes.

Pharmacokinetics:

Absorption: Readily and completely absorbed from GI tract. Time to peak plasma concentration: 1-2 hr.

Metabolism: Undergoes partial hepatic metabolism.

Excretion: Via urine 80-90% (unchanged). Half-life: Approx 3-5 hr.

How should I take Shacold?

Take Shacold exactly as directed by your doctor, or follow the instructions that accompany the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Never take this medication in larger doses or more often than is recommended. Too much Shacold could be very harmful.

If your symptoms are accompanied by a high fever, or if they do not improve in 7 days, see your doctor.

Store Shacold at room temperature away from moisture and heat.

Shacold pharmacology

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Shacold (PPA), a sympathomimetic agent structurally similar to pseudoephedrine, is used to treat nasal congestion. Shacold is found in appetite suppressant formulations and with guaifenesinin in cough-cold formulations. In 2000, the FDA requested that all drug companies discontinue marketing products containing Shacold, due to an increased risk of hemorrhagic stroke in women who used Shacold.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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