Shen Min Vitamin Overdose

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Consists of Vitamin A, Vitamin B3, Vitamin B5, Vitamin B6, Vitamin H

What happens if I overdose Vitamin A (Shen Min Vitamin)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of vitamin A can cause serious or life-threatening side effects.

Overdose symptoms may include nausea, vomiting, loss of appetite, vision changes, hair loss, peeling skin, cracked skin around your mouth, changes in menstrual periods, dizziness, drowsiness, tired feeling, bone or joint pain, severe headache, pain behind your eyes, severe stomach pain, dark urine, or jaundice (yellowing of the skin or eyes).

Overdose of Vitamin A (Shen Min Vitamin) in details

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The following amounts have been found to be toxic orally. Toxicity manifestations depend on the age, dosage, size, and duration of administration.

Acute toxicity — single dose (25,000 Units/kg body weight)

Infant: 350,000 Units

Adult: Over 2 million Units

Chronic toxicity (4,000 Units/kg body weight for 6 to 15 months)

Infants 3 to 6 months old: 18,500 Units (water dispersed)/day for 1 to 3 months.

Adult: 1 million Units daily for three days; 50,000 Units daily for longer than 18 months; 500,000 Units daily for two months.

Hypervitaminosis A Syndrome:

1.
General manifestations:

Fatigue, malaise, lethargy, abdominal discomfort, anorexia, and vomiting.

2.
Specific manifestations:
a. Skeletal: hepatotoxicity, hard tender cortical thickening over the radius and tibia, migratory arthralgia, slow growth, and premature closure of the epiphysis leading to arrested bone growth in children.

b. Central Nervous System: irritability, headache, and increased intracranial pressure as manifested by bulging fontanels, papilledema, and exophthalmos.

c. Dermatologic: fissures of the lips, drying and cracking of the skin, alopecia, scaling, massive desquamation, and increased pigmentation.

d. Systemic: hypomenorrhea, hepatosplenomegaly, hepatotoxicity, jaundice, leukopenia, vitamin A plasma level over 1,200 Units/100 mL.

The treatment of hypervitaminosis A consists of immediate withdrawal of the vitamin along with symptomatic and supportive treatment.

What should I avoid while taking Vitamin A (Shen Min Vitamin)?

Avoid taking orlistat (alli, Xenical) or mineral oil while you are taking vitamin A.

Vitamin A (Shen Min Vitamin) warnings

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Avoid overdosage. Keep out of the reach of children.

Pediatric Use: Polysorbates have been associated with E-Ferol syndrome (thrombocytopenia, renal dysfunction, hepatomegaly, cholestasis, ascites, hypotension and metabolic acidosis) in low birth-weight infants.

What should I discuss with my healthcare provider before taking Vitamin A (Shen Min Vitamin)?

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

Vitamin A (Shen Min Vitamin) precautions

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General: Protect from light. Prolonged daily dose administration over 25,000 Units vitamin A should be under close supervision. Blood level assays are not a direct measure of liver storage. Liver storage should be adequate before discontinuing therapy. Single vitamin A deficiency is rare. Multiple vitamin deficiency is expected in any dietary deficiency.

Drug Interactions: Women on oral contraceptives have shown a significant increase in plasma vitamin A levels.

Carcinogenesis: There are no studies that show that administration of vitamin A will cause or prevent cancer.

Pregnancy Category X:

Nursing Mothers: The U.S. Recommended Daily Allowance (RDA) of vitamin A (5,000 Units) is recommended for nursing mothers.

What happens if I miss a dose of Vitamin A (Shen Min Vitamin)?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Vitamin B3 (Shen Min Vitamin) warnings

Patient Information

Diabetic patient and patient with liver problems or peptic ulcer should tak niacin with caution and should monitor liver funtion test, blood glucos frequently.

Vitamin B3 (Shen Min Vitamin) should also used with caution in patients with elevated uric acid levels gout, unstable angina, and acute phase of myocardial infarction

Vitamin B3 (Shen Min Vitamin) may interact with some antihypertensive drugs, aspirin, and alcohol. Patient shoul check with a health professional before start taking niacin or start a new medication.

Vitamin B3 (Shen Min Vitamin) precautions

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For external use only. If irritation occurs, wash product off, discontinue use and consult a physician. Avoid contact with eyes.

Vitamin B5 (Shen Min Vitamin) warnings

In case of observation of hypersensitivity to any ingredient of the product the treatment should be discontinued. Topical preparations of dexpanthenol should not be used as dietary supplement.

Pregnancy –It can be used safely.

Breast-feeding- It can be used safely.

Geriatrics- It can be used safely.

Pediatrics- It can be used safely.

What happens if I overdose Vitamin B6 (Shen Min Vitamin)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking Vitamin B6 (Shen Min Vitamin)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Vitamin B6 (Shen Min Vitamin) warnings

Pregnancy

Category A. ( Category C in doses that exceed the RDA.)

Lactation

Excreted in breast milk; may inhibit lactation.

Children

Safety and efficacy not established in doses exceeding nutritional requirements.

What should I discuss with my healthcare provider before taking Vitamin B6 (Shen Min Vitamin)?

You should not use pyridoxine if you have ever had an allergic reaction to it.

Ask a doctor or pharmacist if it is safe for you to use this medicine if:

To make sure you can safely receive injectable pyridoxine, tell your doctor if you have heart disease or kidney disease.

FDA pregnancy category A. Pyridoxine is not expected to harm an unborn baby. Your pyridoxine dose needs may be different during pregnancy. Do not use pyridoxine without medical advice if you are pregnant or plan to become pregnant.

Pyridoxine can pass into breast milk. Your dose needs may be different while you are nursing. High doses of this medication may harm a nursing baby. Do not use pyridoxine without medical advice if you are breast-feeding a baby.

Do not give this medicine to a child without medical advice.

What happens if I miss a dose of Vitamin B6 (Shen Min Vitamin)?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not Use extra medicine to make up the missed dose.

Vitamin H (Shen Min Vitamin) warnings

Pregnant women and nursing mothers should consult their physicians before taking this product. Appearex® should not be used in patients with known allergy or hypersensitivity to any of its ingredients.

TOXICITY

No toxic effects have been reported, even at higher doses.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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