What is Sodium Hyaluronate Gel?
Sodium Hyaluronate Gel is similar to the fluid that surrounds your joints. Sodium Hyaluronate Gel acts as a lubricant on the skin by restoring moisture and preventing friction or abrasion.
Sodium Hyaluronate Gel topical skin medication is used to treat skin ulcers such as bed sores or diabetic foot ulcers, as well as burn wounds, surgical incisions, cuts, abrasions, and other skin irritations. Sodium Hyaluronate Gel skin medication is also used to treat dry or scaly skin.
Sodium Hyaluronate Gel oral gel is used to treat mouth sores or other irritation caused by infection, chemotherapy or radiation treatments, or dental work.
Sodium Hyaluronate Gel topical may also be used for purposes not listed in this medication guide.
Sodium Hyaluronate Gel indications
Sodium Hyaluronate Gel (1% Sodium Hyaluronate Gel) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics (e.g., acetaminophen).
How should I use Sodium Hyaluronate Gel?
Use Sodium Hyaluronate Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Sodium Hyaluronate Gel. Talk to your pharmacist if you have questions about this information.
- Sodium Hyaluronate Gel is given as an injection into the knee joint at your doctor's office, hospital, or clinic.
- Sodium Hyaluronate Gel is usually given as a series of injections 1 week apart for a total of 3 to 5 injections depending on the particular product you are using. You may not experience relief until you have received several injections.
- Do not use Sodium Hyaluronate Gel if it contains particles, is cloudy or discolored, or if the vial or syringe is cracked or damaged.
- Do not use disinfectants containing ammonium salts to prepare the skin for injection because side effects may occur.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Sodium Hyaluronate Gel, contact your doctor to establish a new dosing schedule.
Ask your health care provider any questions you may have about how to use Sodium Hyaluronate Gel.
Uses of Sodium Hyaluronate Gel in details
This medication is used to protect skin ulcers, burns, or wounds from irritation so that the skin can heal properly. Hyaluronate is the same as a natural substance that is found in your body. It works by forming a protective layer over the affected area.
How to use Sodium Hyaluronate Gel topical
Use this product on the skin only. Wash your hands before and after each use. Before using, wash and disinfect the affected area as directed by your doctor. Gently apply a thin layer of the medication to the affected areas of the skin, usually 2 to 3 times daily or as directed by your doctor. Cover the affected area as directed.
How often you apply the medication is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.
Tell your doctor if your condition persists or worsens.
Sodium Hyaluronate Gel description
Each mL of Sodium Hyaluronate Gel contains Sodium Hyaluronate 10 mg. It also contains the following inactive ingredients: Sodium chloride 8.5 mg, disodium hydrogen phosphate dodecahydrate 0.56 mg, sodium dihydrogen phosphate dihydrate 0.05 mg and water for injections.
Sodium Hyaluronate Gel is a viscoelastic, sterile solution of highly purified, high molecular weight (2.4-3.6 million daltons) Sodium Hyaluronate Gel in phosphate-buffered saline. Sodium Hyaluronate Gel is a physiological material found in both animal and human tissues. Sodium Hyaluronate Gel is a very highly purified product extracted from bacterial cells. It is a polysaccharide consisting of a repeating disaccharide of N-acetylglucosamine and sodium glucuronate, linked by alternating β-1,3 and β-1,4 glycosidic bonds. Hyaluronate can be found in synovial fluid, in the vitreous and aqueous humor of the eye, in skin and in the umbilical cord. The contents of the Sodium Hyaluronate Gel syringe are sterile (aseptic filling) and the external surface of the blister-packed syringe is sterilized by ethylene oxide sterilization.
Sodium Hyaluronate Gel dosage
Usual Dose: 2 mL injected into the affected knee at weekly intervals of 3 weeks, for a total of 3 injections. For the best effect, all 3 injections must be administered.
Administration: Sodium Hyaluronate Gel is intended for injection into the synovial space. Each Sodium Hyaluronate Gel syringe is intended for single use only. The syringe should be used immediately after the individual syringe blister is opened. Do not use Sodium Hyaluronate Gel if the package is opened or has been tampered with or damaged.
Bring the Sodium Hyaluronate Gel syringe to room temperature before use. Use aseptic technique when handling the syringe and administering the injection. See Instructions for Use under Cautions for Usage for details of preparing the syringe for use.
If the patient presents with effusion, the effusion should be removed before Sodium Hyaluronate Gel is injected into the joint.
Inject the contents of the syringe (2 mL) into 1 knee only. Discard any unused Sodium Hyaluronate Gel. If treatment is being administered to both knees, use a separate syringe for each knee.
For patients who respond to treatment, the effect of treatment lasts for at least 26 weeks.
Sodium Hyaluronate Gel interactions
See also:
What other drugs will affect Sodium Hyaluronate Gel?
None currently known.
Incompatibilities: Mixing of quaternary ammonium salts eg, benzalkonium chloride with Sodium Hyaluronate Gel solutions results in formation of a precipitate. Sodium Hyaluronate Gel should not be administered through a needle previously used with medical solutions containing benzalkonium chloride. Do not use disinfectants for skin preparation that contain quaternary ammonium salts.
Sodium Hyaluronate Gel side effects
See also:
What are the possible side effects of Sodium Hyaluronate Gel?
Applies to Sodium Hyaluronate Gel: injection gel/jelly, injection solution
As well as its needed effects, Sodium Hyaluronate Gel (the active ingredient contained in Sodium Hyaluronate Gel) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking Sodium Hyaluronate Gel, check with your doctor immediately:
Less common:
- Blue color or flushing or redness of skin
- cough
- difficulty in swallowing
- dizziness or feeling faint (severe)
- fever
- redness or pain at place of injection
- skin rash, hives, and/or itching
- stuffy nose
- swelling of eyelids, face, or lips
- tightness in chest, troubled breathing, and/or wheezing
Minor Side Effects
Some Sodium Hyaluronate Gel side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
More common:
- Diarrhea
- headache
- itching of the skin
- large, nonelevated blue or purplish patches in the skin
- loss of appetite
- nausea and/or vomiting
- stomach pain
- swelling of the knee
Sodium Hyaluronate Gel contraindications
See also:
What is the most important information I should know about Sodium Hyaluronate Gel?
- Do not use Sodium Hyaluronate Gel to treat patients who have a known hypersensitivity to hyaluronan preparations.
- Do not use Sodium Hyaluronate Gel to treat patients with knee joint infections, infections or skin disease in the area of the injection site.
Active ingredient matches for Sodium Hyaluronate Gel:
List of Sodium Hyaluronate Gel substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| HYOPT (India) | |
| 30 mg x 1 mL x 1's (Virchow) | |
| Hyopt 14mg x 1mL INJ / 1 (Virchow) | |
| Hyopt 30mg x 1mL INJ / 1 (Virchow) | |
| HYOPT inj 14 mg x 1 mL x 1ml (Virchow) | |
| HYOPT inj 30 mg x 1 mL x 1ml (Virchow) | |
| Hyopt 14mg x 1mL INJ / 1 (Virchow) | |
| Hyopt 30mg x 1mL INJ / 1 (Virchow) | |
| HYVISC 0.1 (India) | |
| 0.1 % x 5ml | $ 1.10 |
| Hyvisc Forte (India) | |
| Hyvisc Forte 1.8mg x 1mL EYE-DPS / 10ml (Sun (Avesta)) | $ 2.19 |
| HYVISC FORTE eye drops 1.8 mg x 1 mL x 10ml (Sun (Avesta)) | $ 2.19 |
| HYVISC PLUS (India) | |
| HYVISC PLUS Eye Drops / 14mg per ml / 0.55ml units (Sun Pharmaceutical Industries Ltd.) | $ 9.78 |
| 0.18 % x 7ml (Sun Pharmaceutical Industries Ltd.) | $ 2.06 |
| Hyvisc Plus 0.18% EYE-DPS / 7ml (Sun Pharmaceutical Industries Ltd.) | $ 2.06 |
| Hyvisc Plus 10 mg Injection (Sun Pharmaceutical Industries Ltd.) | $ 10.54 |
| Hyvisc Plus Eye Drop (Sun Pharmaceutical Industries Ltd.) | $ 2.06 |
| HYVISC PLUS eye drops 0.18 % x 7ml (Sun Pharmaceutical Industries Ltd.) | $ 2.06 |
| Hyvisc Plus 0.18% EYE-DPS / 7ml (Sun Pharmaceutical Industries Ltd.) | $ 2.06 |
| Hyvisc-0.1 (India) | |
| Hyvisc-0.1 0.1% EYE-DPS / 5ml (Sun (Avesta)) | $ 1.10 |
| HYVISC-0.1 eye drops 0.1 % x 5ml (Sun (Avesta)) | $ 1.10 |
| Hyvisc-0.55 (India) | |
| Hyvisc-0.55 10mg x 1mL Syringe / 0.55ml (Sun (Avesta)) | $ 9.94 |
| HYVISC-0.55 intraocular inj 10 mg x 1 mL x 0.55ml (Sun (Avesta)) | $ 9.94 |
| Ial-System (India) | |
| Ial-System 20mg x 1.1mL INJ / 1.1ml (Ranbaxy) | $ 3.01 |
| IAL-SYSTEM inj 20 mg x 1.1 mL x 1.1ml (Ranbaxy) | $ 3.01 |
| IPM Wound | |
| KINEFLEX ONE (India) | |
| KINEFLEX ONE inj 48 mg x 6 mL x 6ml (Kinedex) | $ 120.47 |
| LACRITO (India) | |
| LG HYAL 2000 (India) | |
| 0.85ml (LGLSI) | $ 14.46 |
| LG Hyal 2000 - INJ / 0.85mg (LGLSI) | $ 14.46 |
| LG HYAL 2000 inj 10 mg x 0.85ml (LGLSI) | $ 14.46 |
| LG Hyal 2000 - INJ / 0.85mg (LGLSI) | $ 14.46 |
| Optrex contact lens friendly eye drops (United Kingdom) | |
| RadiaPlexRx | |
| Sodium Chondroitin and Sodium Hyaluronate | |
| Sodium Hyaluronate | |
| sodium hyaluronate injection | |
| Supartz | |
| Visconix INJ (India) | |
| Visconix INJ Na hyaluronate 1% w/v, NaCl0.85% w/v PFS / 2ml (Cadila (Vibra)) | |
| 2ml (Cadila (Vibra)) | |
| VISCONIX INJ inj 2ml (Cadila (Vibra)) | |
| VISIAL INJ. | |
| VISIAL INJ. Prefilled Syringe / 1/ % / 0.8ml units (Cadila Pharmaceuticals (Le Sante Division)) | $ 8.77 |
| Xclair | |
See 68 substitutes for Sodium Hyaluronate Gel | |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
