Actions of Solvex in details
Solvex, a derivative of acetylcysteine, is a mucoregulating agent. Its major action is thought to be on the metabolism of mucus-producing cells. The mucus produced under the influence of Solvex has an increased content of the less viscous sialomucin and a reduced content of the highly viscous fucomucin. Sialomucins influence the rheological properties of mucus and may also, through the inhibition of kinins, reduce or prevent bronchial inflammation and bronchospasm.
Solvex is rapidly and well-absorbed after oral administration. Following oral administration of 1.5 g Solvex, peak serum concentration of 13-16 mg/L was reached in 1-2 hrs. Plasma t½ was 1.5-2 hrs. Solvex penetrates well into lung tissues and respiratory mucus suggesting local action. Solvex undergoes acetylation, decarboxylation and sulfoxidation. Majority of Solvex is excreted unchanged in the urine.
Solvex administration
Should be taken with food.
Solvex pharmacology
Solvex enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies.
References
- EPA DSStox. "Bromhexine: DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". https://comptox.epa.gov/dashboard/ds... (accessed September 17, 2018).
- EPA DSStox. "Reboxetine: DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". https://comptox.epa.gov/dashboard/ds... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Solvex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Solvex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported administration
When best can I take Solvex, on an empty stomach, before or after food?ndrugs.com website users have also released a report stating that Solvex should be taken After food. In any case, this may not be the right description on how you ought to take this Solvex. Kindly visit your doctor for more medical advice in this regard. Click here to see other users view on when best the Solvex can be taken.
| Users | % | ||
|---|---|---|---|
| After food | 1 | 100.0% | |
Consumer reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology
