Dosage of Spir in details
Spir Dosage
Generic name: Spir DIPROPIONATE 40ug
Dosage form: aerosol, metered
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Administration Information
Administer Spir by the orally inhaled route only. Patients should prime Spir by actuating into the air twice before using for the first time or if Spir has not been used for over 10 days. Avoid spraying in the eyes or face when priming Spir. Spir is a solution aerosol, which does not require shaking. Consistent dose delivery is achieved, whether using the 40 or 80 mcg strengths, due to proportionality of the 2 products (i.e., 2 actuations of 40 mcg strength should provide a dose comparable to 1 actuation of the 80 mcg strength). Rinsing the mouth after inhalation is advised.
Spir has a dose counter attached to the actuator. When the patient receives the inhaler, a black dot will appear in the viewing window until it has been primed 2 times, at which point the total number ofactuations will be displayed. The dose counter will count down each time a spray is released. The dose-counter window displays the number of sprays left in the inhaler in units of two (e.g., 120, 118, 116, etc). When the dose counter reaches 20, the color of the numbers will change to red to remind the patient to contact their pharmacist for a refill of medication or consult their physician for a prescription refill. When the dose counter reaches 0, the background will change to solid red.
Discard Spir inhaler when the dose counter displays 0 or after the expiration date on the product, whichever comesfirst.
Maintenance Treatment of Asthma
Spir should be administered by the oral inhaled route in patients 5 years of age and older. Use of Spir with a spacer device in children less than 5 years of age is not recommended. [seeUse in Specific Populations (8.4)] The onset and degree of symptom relief will vary in individual patients. Improvement in asthma symptoms can occur within 24 hours of the beginning of treatment and should be expected within the first or second week, but maximum benefit should not be expected until 3 to 4 weeks of therapy. For patients who do not respond adequately to the starting dose after 3 to 4 weeks of therapy, higher doses may provide additional asthma control. The safety and efficacy of Spir when administered in excess of recommended doses has not been established.
| Patient’s Previous Therapy | Recommended Starting Dose | Highest Dose Recommended |
|---|---|---|
| Bronchodilators Alone | 40 to 80 mcg twice daily | 320 mcg twice daily |
| Inhaled Corticosteroids | 40 to 160 mcg twice daily | 320 mcg twice daily |
| Patient’s Previous Therapy | Recommended Starting Dose | Highest Dose Recommended |
|---|---|---|
| Bronchodilators Alone | 40 mcg twice daily | 80 mcg twice daily |
| Inhaled Corticosteroids | 40 mcg twice daily | 80 mcg twice daily |
As with any inhaled corticosteroid, physicians are advised to titrate the dose of Spir downward over time to the lowest level that maintains proper asthma control. This is particularly important in children since a controlled study has shown that Spir has the potential to affect growth in children. Patients should be instructed on the proper use of their inhaler.
Patients Not Receiving Systemic Corticosteroids
Patients who require maintenance therapy of their asthma may benefit from treatment with Spir at the doses recommended above. In patients who respond to Spir, improvement in pulmonary function is usually apparent within 1 to 4 weeks after the start of therapy. Once the desired effect is achieved, consideration should be given to tapering to the lowest effective dose.
Patients Maintained on Systemic Corticosteroids
Prednisone or other oral corticosteroid should be weaned slowly beginning after at least 1 week of Spir therapy. Monitor patients carefully for signs of asthma instability, including serial objective measures of airflow, and for signs of adrenal insufficiency during steroid taper and following discontinuation of oral corticosteroid therapy.
More about Spir (Spir)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Espanol
- 23 Reviews - Add your own review/rating
Consumer resources
- Spir aerosol solution
- Spir
- Spir (Advanced Reading)
- Other brands: Beclovent
Professional resources
- Spir (AHFS Monograph)
- Spir (FDA)
Related treatment guides
- Asthma, Maintenance
- Bronchitis
What other drugs will affect Spir?
If you also use a bronchodilator (a drug that opens the airways to improve breathing), use it first before using the Spir inhaler. This will allow more Spir to reach your lungs. Bronchodilators include albuterol (Proventil, Ventolin), pirbuterol (Maxair), bitolterol (Tornalate), and others.
Other drugs may interact with Spir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
Spir interactions
No drug interactions have been described with inhaled Spir.
Reviews
The results of a survey conducted on ndrugs.com for Spir are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Spir. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported frequency of use
No survey data has been collected yetConsumer reported doses
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Information checked by Dr. Sachin Kumar, MD Pharmacology
