T-Minic DPS indications
Infectious-inflammatory diseases caused by microorganisms susceptible to ciprofloxacin, including respiratory diseases, diseases of abdominal and pelvic organs, bones, joints, skin, septicemia; severe infections of ENT organs. Treatment of postoperative infections. Prevention and treatment of infections in patients with reduced immunity.
For T-Minic DPS Citadel Fine Pharmaceuticals local use: acute and subacute conjunctivitis, blepharoconjunctivitis, blepharitis, bacterial corneal ulcers, keratitis, keratoconjunctivitis, chronic dacryocystitis, meybomity. Infectious lesions in the eyes from injury or contact with foreign bodies. Preoperative prophylaxis in ophthalmic surgery.
T-Minic DPS description
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine. [PubChem]
T-Minic DPS dosage
Individual. For oral administration dose of T-Minic DPS Citadel Fine Pharmaceuticals is 250-750 mg 2 times / day. Treatment duration is from 7-10 days to 4 weeks.
For IV administration a single dose is 200-400 mg, the multiplicity of the introduction is 2 times / day, duration of treatment - 1-2 weeks and more if necessary. May be IV injected as jet but more preferably a drip for 30 minutes.
When T-Minic DPS Citadel Fine Pharmaceuticals applied topically instilled 1-2 drops into the lower conjunctival sac of the affected eye every 1-4 hours. After improving the intervals between instillation can be increased. The maximum oral daily dose for adults is 1.5 g.
T-Minic DPS interactions
Activity increases when combined with beta-lactam antibiotics, aminoglycosides, vancomycin, clindamycin, metronidazole. Sukralfat, bismuth preparations, antacids containing aluminum ions, magnesium or calcium, cimetidine, ranitidine, vitamin and mineral supplement, iron sulfate, zinc, didanosine (recommended for 2 hours before or 4 hours after these drugs) reduce the suction. Probenecid, azlocillin increase the concentration in the blood. Decreases clearance and increases in plasma caffeine, aminophylline and theophylline (increased likelihood of side effects). T-Minic DPS Citadel Fine Pharmaceuticals enhances the effect of warfarin and other oral anticoagulants (prolongs bleeding time). Increases nephrotoxicity of cyclosporine, increase the risk of CNS excitability and convulsive reactions against the background of NSAIDs. Medicines alkalinizing the urine (citrates, sodium bicarbonate, carbonic anhydrase inhibitors) reduce the solubility (increases the probability of crystalluria). Infusion solutions of ciprofloxacin ready to use can be combined with infusion solutions: 0.9% sodium chloride solution, Ringer's solution, Ringer lactate, 5 and 10% dextrose, 10% solution of fructose, and a solution containing 5% dextrose with 0,225 or 0.45% sodium chloride. Incompatible with solutions having a pH > 7.
T-Minic DPS side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Rare
Fever
skin rash or itching
sore throat and fever
unusual tiredness and weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Abdominal or stomach pain or upset
diarrhea
nausea or vomiting
Rare
Dizziness
hair loss
headache
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
T-Minic DPS contraindications
Injection: T-Minic DPS is contraindicated in comatose states, in patients who have received large amounts of central-nervous-system depressants (alcohol, sedative hypnotics, including barbiturates, general anesthetics, narcotics, narcotic analgesics, tranquilizers, etc.), and in patients who have demonstrated an idiosyncrasy or hypersensitivity to promethazine.
Under no circumstances should promethazine be given by intra-arterial injection due to the likelihood of severe arteriospasm and the possibility of resultant gangrene
T-Minic DPS HCl injection should not be given by the subcutaneous route; evidence of chemical irritation has been noted, and necrotic lesions have resulted on rare occasions following subcutaneous injection. The preferred parenteral route of administration is by deep intramuscular injection.
Syrup, Tablets and Suppositories: Phenergan Tablets and Suppositories are contraindicated for use in pediatric patients less than two years of age.
Phenergan Tablets and Suppositories are contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines.
Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms including asthma.
Active ingredient matches for T-Minic DPS:
Chlorphenamine in India.
Chlorphenamine maleate/phenylephrine hydrochloride in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| T-Minic DPS Chlorepheniramine maleate 2mg, Phenylephrine HCI 5mg/5mL DPS / 15ml | $ 0.42 |
| 15ml | $ 0.42 |
| T-Minic Dps Chlorphenamine maleate 2 mg, Phenylephrine hydrochloride 5mg/5 mL. DPS / 15ml | $ 0.42 |
| T-MINIC DPS oral drops 15ml (Novartis (OTC)) | $ 0.64 |
| T-Minic Dps Chlorphenamine maleate 2 mg, Phenylephrine hydrochloride 5mg/5 mL. DPS / 15ml | $ 0.42 |
List of T-Minic DPS substitutes (brand and generic names): | |
| T-Minic SYP (India) | |
| T-Minic Syp Chlorphenamine maleate 2 mg, Phenylephrine hydrochloride 5mg/5 mL. SYR / 60ml (Novartis (OTC)) | $ 0.45 |
| Tacof D | |
| Tacof D 60 ml Syrup (Biostrass Health Sciences) | $ 0.04 |
| TACOF D 5MG/2MG/10MG SYRUP 1 bottle / 60 ML syrup each (Biostrass Health Sciences) | $ 0.46 |
| TACOF D SYRUP 1 bottle / 100 ML syrup each (Biostrass Health Sciences) | $ 0.66 |
| Tacof D 5 mg/2 mg/10 mg Syrup (Biostrass Health Sciences) | $ 0.46 |
| Tacof D Syrup (Biostrass Health Sciences) | $ 0.66 |
| Tacof P | |
| Tacof P 15 ml Drop (Biostrass Health Sciences) | $ 0.02 |
| Tacof P 60 ml Syrup (Biostrass Health Sciences) | $ 0.03 |
| TACOF P 500MG/2.5MG/1MG DROP 1 packet / 15 ML drop each (Biostrass Health Sciences) | $ 0.42 |
| Tacof P Drop (Biostrass Health Sciences) | $ 0.42 |
| Teldrin (United States) | |
| Capsule, Extended Release; Oral; Chlorpheniramine Maleate 8 mg (Smithkline beecham consumer) | |
| Capsule, Extended Release; Oral; Chlorpheniramine Maleate 12 mg (Smithkline beecham consumer) | |
| Tisko (India) | |
| Tisko phenylephrine hydrochloride 5mg, Paracetamol 325 mg, cetirizine 5 mg, caffeine 15mg. TAB / 10 (Eltis) | |
| TISKO tab 10's (Eltis) | |
| Tisko Syr (India) | |
| Tisko Syr Phenylephrine hydrochloride2.5 mg, paracetamol 125 mg, cetirizine 1 mg. SYR / 60ml (Eltis) | |
| TISKO SYR syr 60ml (Eltis) | |
| Tpdrops | |
| Tpdrops Eye 5 ml Drop (Indo-Reh Pharmaceuticals) | $ 0.12 |
| Treatcold (India) | |
| Treatcold phenylephrine 5 mg, paracetamol 500 mg, Chlorphenamine maleate 2 mg, caffeine 15 mg. TAB / 10 (Treatwell) | $ 0.22 |
| TREATCOLD tab 10's (Treatwell) | $ 0.22 |
| Treatcold Syr (India) | |
| Treatcold Syr Paracetamol 125 mg, phenylephrine hydrochloride2.5 mg, chlorpheniraminemaleate 1.25 mg, bromhexine 4mg. SYR / 60ml (Treatwell) | $ 0.54 |
| TREATCOLD SYR syr 60ml (Treatwell) | $ 0.54 |
| Triaminic Decongestant Infant Orally Disintegrating Strips | |
| Triaminic Thin Strips (United States) | |
| Triaminic Thin Strips Cold (United States) | |
| Triaminic Thin Strips Cold with Stuffy Nose | |
| Triaminic Thin Strips Congestion | |
| Strip; Oral; Phenylephrine Hydrochloride 2.5 mg | |
| Triaminic Thin Strips Nasal Congestion (Canada) | |
| Strip; Oral; Phenylephrine Hydrochloride 2.5 mg (Novartis consumer) | |
| Triaminic Thin Strips Nasal Congestion strip 2.5 mg (Novartis consumer) | |
| Triaminic Toddler Congestion Thin Strips | |
| Strip; Oral; Phenylephrine Hydrochloride 2.5 mg | |
| Triaminic Toddler Congestion Thin Strips strip 2.5 mg (Novartis Consumer Health Canada Inc. (Canada)) | |
| Trigenic CS | |
| Trigenic CS 60 ml Syrup (Trigenesis Lifesciences Pvt. Ltd.) | $ 0.03 |
| Trimeton (Italy) | |
| Tromide Plus | |
| Tromide Plus Eye 5 ml Drop (Entod Pharmaceuticals Ltd) | $ 0.11 |
| Tromide Plus Eye 3 ml Drop (Entod Pharmaceuticals Ltd) | $ 0.16 |
| TROMIDE PLUS 5%/0.8% EYE DROPS 1 packet / 5 ML eye drop each (Entod Pharmaceuticals Ltd) | $ 0.58 |
| Tromide Plus 5% w/v/0.8% w/v Eye Drop (Entod Pharmaceuticals Ltd) | $ 0.58 |
| Tropifrin | |
| Tropifrin Eye 3 ml Drop (Jawa Pharmaceuticals (India) Pvt. Ltd.) | $ 0.11 |
| TROPIFRIN 5%/0.8% EYE DROPS 1 packet / 3 ML eye drop each (Jawa Pharmaceuticals (India) Pvt. Ltd.) | $ 0.74 |
| TROPIFRIN 5%W/V/0.8%W/V EYE DROPS 1 packet / 5 ML eye drop each (Jawa Pharmaceuticals (India) Pvt. Ltd.) | $ 0.82 |
| Tropifrin 5% w/v/0.8% w/v Eye Drop (Jawa Pharmaceuticals (India) Pvt. Ltd.) | $ 0.74 |
| Tropifrin 5% w/v/0.8 (Jawa Pharmaceuticals (India) Pvt. Ltd.) | $ 0.82 |
| TRUSTYL-COLD (India) | |
| 60ml (AHPL) | $ 0.33 |
See 1692 substitutes for T-Minic DPS | |
References
- PubChem. "phenylephrine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "phenylephrine". http://www.drugbank.ca/drugs/DB00388 (accessed September 17, 2018).
- MeSH. "Cardiotonic Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
