Tatanol Plus Uses

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Tatanol Plus indications

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Management of duodenal ulcer; treatment of gastroesophageal reflux disease (GERD), including erosive esophagitis; therapy for benign gastric ulcer; treatment of pathologic hypersecretory conditions; prevention of upper GI bleeding.

Unlabeled Uses

Prevention of aspiration pneumonia and stress ulcers; herpes virus infection; chronic idiopathic urticaria; anaphylaxis (relieves dermatologic symptoms only); dyspepsia; used before anesthesia to prevent aspiration pneumonitis; treatment of hyperparathyroidism and control of secondary hyperparathyroidism in chronic hemodialysis patient; treatment of chronic viral warts in children.

Tatanol Plus description

Each caplet contains acetaminophen 500 mg and Caffeine (Tatanol Plus) 65 mg.

Tatanol Plus dosage

Adults and Children ≥12 years: Take 1-2 caplets, every 4-6 hours as required. Do not take more frequently than every 4 hrs. Do not take more than 8 caplets in 24 hours. It can be taken on an empty stomach.

Panadol Extra Advance should not be used with other acetaminophen-containing products. Do not exceed the stated dose.

Tatanol Plus interactions

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The speed of absorption of Paracetamol (Tatanol Plus) may be increased by metoclopramide or domperidone and absorption reduced by colestyramine.

The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular use of Paracetamol (Tatanol Plus) with increased risk of bleeding. Occasional doses have no significant effect.

The use of drugs which induce hepatic microsomal enzymes, such as anticonvulsants and oral contraceptive steroids, may increase the extent of metabolism of Paracetamol (Tatanol Plus), resulting in reduced plasma concentrations of the drug and a faster elimination rate.

Drugs which induce hepatic microsomal enzymes, such as alcohol and barbiturates, may increase the hepatotoxicity of Paracetamol (Tatanol Plus), particularly after overdose.

CNS depression or excitation may occur if codeine is given to patients receiving monoamine oxidase inhibitors, or within two weeks of stopping treatment with them. The effects of CNS depressants (including alcohol) may be potentiated by codeine.

Concurrent use of codeine with antidiarrhoeal and antiperistaltic agents may increase the risk of severe constipation. Concomitant use of antimuscarinics or medications with antimuscarinic action may result in an increased risk of severe constipation, which may lead to paralytic ileus and/or urinary retention.

Quinidine can inhibit the analgesic effect of codeine.

Codeine may delay the absorption of mexiletine and thus reduce the antiarrhythmic effect of the latter. Codeine may antagonise the gastrointestinal effects of metoclopramide and domperidone. Cimetidine inhibits the metabolism of opioid analgesics resulting in increased plasma concentrations.

Naltrexone blocks the therapeutic effect of opioids.

Tatanol Plus side effects

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Adverse effects of Paracetamol (Tatanol Plus) are rare, but hypersensitivity including skin rash may occur. There have been a few reports of blood dyscrasias including thrombocytopenia and agranulocytosis, but these were not necessarily causally related to Paracetamol (Tatanol Plus).

Codeine can produce constipation and drowsiness. Occasional effects are nausea, vomiting, sweating, facial flushing, dry mouth, blurred or double vision, dizziness, postural hypotension, headache, vertigo, palpitations, allergic reactions (itch, skin rash, facial oedema), and difficulties in micturition (dysuria, increased frequency, decrease in amount). Side-effects which occur rarely include hallucinations, nightmares, restlessness and stomach cramps. The frequency and severity are determined by dosage, duration of treatment and individual sensitivity and are unlikely at this dosage. Tolerance and dependency can occur, especially with prolonged high doses of codeine.

High doses of Caffeine (Tatanol Plus) may produce headache, tremor, nervousness and irritability.

Tatanol Plus contraindications

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Do not use with an MAOI or within 14 days of discontinuing an MAOI

due to risk of drug interaction. At least 5 weeks should be allowed after

stopping FLUOXETINE before treatment with an MAOI

• Do not use with pimozide due to risk of drug interaction or QTc

prolongation

• Do not use with thioridazine due to QTc interval prolongation or

potential for elevated thioridazine plasma levels. Do not use thioridazine

within 5 weeks of discontinuing FLUOXETINE

Active ingredient matches for Tatanol Plus:

Caffeine/Paracetamol in Vietnam.


Unit description / dosage (Manufacturer)Price, USD
Tatanol Plus 20 Blister x 4 Tablet, 10 Blister x 10 Tablet
Tatanol Plus 20 Blister x 4 Tablet
Tatanol Plus 10 Blister x 10 Tablet

List of Tatanol Plus substitutes (brand and generic names):

Tablet; Oral; Acetaminophen; 500 mg; Caffeine 30 mg (Novartis)
Solution; Oral; Acetaminophen 405 mg; Caffeine Monohydrate 39.9 mg / 5 ml
Solution; Oral; Acetaminophen 405 mg; Caffeine Monohydrate 39.9 mg / 5 ml
10's (Care Pharma (India) Ltd.)$ 0.27
Thermogesic Plus 500+30 Tablet (Care Pharma (India) Ltd.)$ 0.03
Thermogesic Plus Paracetamol 500 mg, Caffeine30 mg. TAB / 10 (Care Pharma (India) Ltd.)$ 0.27
THERMOGESIC PLUS tab 10's (Care Pharma (India) Ltd.)$ 0.27
Thermogesic Plus Paracetamol 500 mg, Caffeine30 mg. TAB / 10 (Care Pharma (India) Ltd.)$ 0.27
Tiphabangine 2 Blister x 10 Tablet
Tkextra 10 Blister x 10 Tablet
Tozy 10's, 100 x 10's, 1000's (Stadia Biotech)
Tozy 500 mg Tablet (Stadia Biotech)$ 0.24
Travicol Extra 5 Blister x 10 Tablet
Travicol Extra 10 Blister x 10 Tablet
TRIMOL-S 500MG/30MG TABLET 1 strip / 10 tablets each (Ajanta Pharma Ltd)$ 0.23
Tablet; Oral; Acetaminophen 500 mg; Caffeine 65 mg (Mcneil consumer)
U Chiu Analgesic
Vadol Extra 10 Blister x 10 Tablet
Vadol Extra 1 Bottle 100 Tablet
Capsule; Oral; Acetaminophen 250 mg; Caffeine 20 mg (K2 pharmacare)

References

  1. DailyMed. "CAFFEINE; ERGOTAMINE TARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "caffeine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "caffeine". http://www.drugbank.ca/drugs/DB00201 (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Tatanol Plus are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Tatanol Plus. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Tatanol Plus drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Expensive1
100.0%


Consumer reported time for results

No survey data has been collected yet


1 consumer reported age

Users%
16-291
100.0%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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