Consists of Caffeine, Paracetamol
Pregnancy of Caffeine (Tatanol Plus) in details
Caffeine (Tatanol Plus) crosses the placenta; serum concentrations in the fetus are similar to those in the mother (Grosso 2005).
Based on current studies, usual dietary exposure to Caffeine (Tatanol Plus) is unlikely to cause congenital malformations (Brent 2011). However, available data show conflicting results related to maternal Caffeine (Tatanol Plus) use and the risk of other adverse events, such as spontaneous abortion or growth retardation (Brent 2011; Jahanfar 2013; Nehlig 1994). Chronic maternal consumption of high amounts of Caffeine (Tatanol Plus) during pregnancy may lead to neonatal withdrawal at delivery (eg, apnea, irritability, jitteriness, vomiting) (Martin 2007).
The half-life of Caffeine (Tatanol Plus) is prolonged during the second and third trimesters of pregnancy and maternal and fetal exposure is also influenced by maternal tobacco or alcohol consumption (Brent 2011; Koren 2000). Current guidelines recommend limiting Caffeine (Tatanol Plus) intake from all sources to ≤200 mg/day during pregnancy (ACOG 2010).
Caffeine (Tatanol Plus) breastfeeding
Caffeine (Tatanol Plus) citrate is not indicated for use in adult patients. Excreted into human milk: Yes Comments: -Caffeine (Tatanol Plus) readily crosses the placenta into the fetal circulation. -Breastfeeding mothers of infants receiving Caffeine (Tatanol Plus) citrate should not ingest Caffeine (Tatanol Plus)-containing foods, beverages, and medicinal products.
See references
References for pregnancy information
- "Product Information. Cafcit (Caffeine (Tatanol Plus))" Roxane Laboratories Inc, Columbus, OH.
References for breastfeeding information
- "Product Information. Cafcit (Caffeine (Tatanol Plus))" Roxane Laboratories Inc, Columbus, OH.
Pregnancy of Paracetamol (Tatanol Plus) in details
During pregnancy patients should avoid prolonged use of Paracetamol (Tatanol Plus) Zodley Pharmaceuticals because the risk of addiction in the fetus and the occurrence of withdrawal in the neonatal period.
If necessary using in lactation (breastfeeding) should be aware that tramadol in small amounts excreted in breast milk. In the case of long-term treatment can not been excluded the possibility of drug dependence.
Paracetamol (Tatanol Plus) Zodley Pharmaceuticals is not recommended for treatment of withdrawal syndrome drugs.
Patients need to avoid combination with MAO inhibitors.
During the period of treatment with Paracetamol (Tatanol Plus) Zodley Pharmaceuticals you should avoid to take alcohol.
Tramadol in the form of long-acting formulations should not be used in children under the age of 14 years.
During the period of tramadol using is not recommended to engage in activities that require special attention, speed of psychomotor reactions.
References
- DailyMed. "CAFFEINE; ERGOTAMINE TARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubMed Health. "Vivarin: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
- Human Metabolome Database (HMDB). "Caffeine: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).
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Information checked by Dr. Sachin Kumar, MD Pharmacology
