Tenalgin Side effects

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Side effects of Tenalgin in details

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Cardiovascular

Edema; weight gain; CHF; alterations in BP; vasodilation; palpitations; tachycardia.

CNS

Headache; malaise; dizziness; somnolence; vertigo; depression; insomnia; nervousness.

Dermatologic

Pruritus; rash; sweating; erythema; bruising; desquamation; erythema multiforme; toxic epidermal necrolysis.

EENT

Tinnitus; swollen eyes; blurred vision; eye irritation; rhinitis; pharyngitis.

GI

Epigastric distress; nausea; vomiting; anorexia; constipation; stomatitis; abdominal discomfort; diarrhea; flatulence; abdominal pain; indigestion; toxicity (bleeding, ulceration, perforation); heartburn; dyspepsia; anorexia.

Genitourinary

Hematuria; proteinuria; increased BUN and serum creatinine; acute renal insufficiency and failure; papillary necrosis; interstitial nephritis; nephrotic syndrome; hyperkalemia; hyponatremia.

Hematologic

Increased bleeding time; decreased Hgb and Hct; anemia; leukopenia; eosinophilia, thrombocytopenia.

Hepatic

Increased LFTs; elevated liver enzymes.

Respiratory

Bronchospasm; laryngeal edema; dyspnea; hemoptysis; shortness of breath.

Tenalgin contraindications

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Hypersensitivity to Tenalgin, aspirin or other NSAIDs. History of or active peptic ulceration, GI bleeding (melaena, haematemesis) or severe gastritis; severe heart failure. Last trimester of pregnancy.

References

  1. DTP/NCI. "tenoxicam: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
  2. European Chemicals Agency - ECHA. "4-Hydroxy-2-methyl-N-pyridinyl-2H-thieno-[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
  3. NIST. "Tenoxicam". http://www.nist.gov/srd/nist1a.cfm (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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